Kenji Morihisa

ORCID: 0009-0006-1109-864X
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About
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Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Cardiac pacing and defibrillation studies
  • Cardiovascular Syncope and Autonomic Disorders
  • ECG Monitoring and Analysis
  • Complement system in diseases
  • Cardiovascular Health and Disease Prevention
  • Cardiovascular Effects of Exercise
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Disease and Adiposity
  • Cardiovascular Function and Risk Factors
  • Heme Oxygenase-1 and Carbon Monoxide
  • Disaster Response and Management
  • Alcohol Consumption and Health Effects
  • Angiogenesis and VEGF in Cancer
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular and exercise physiology
  • Spectroscopy and Chemometric Analyses
  • Electrochemical Analysis and Applications
  • Coronary Interventions and Diagnostics
  • Cardiovascular Issues in Pregnancy

Saiseikai Kumamoto Hospital
2019-2024

Kumamoto Chuo Hospital
2011-2022

Kumamoto University
2007-2014

Angina without significant stenosis, or nonobstructive coronary artery disease, attracts clinical attention. Microvascular spasm (microvascular CAS) can cause disease. We investigated the features of microvascular CAS and therapeutic efficacy calcium channel blockers.Three hundred seventy consecutive, stable patients with suspected angina presenting arteries (<50% diameter) in angiography were intracoronary acetylcholine provocation test, simultaneous measurements transcardiac lactate...

10.1161/jaha.112.002485 article EN cc-by-nc-nd Journal of the American Heart Association 2012-09-26

Mitral regurgitation is frequently complicated with atrial fibrillation without apparent organic changes in the leaflet, which occasionally improves after successful radiofrequency catheter ablation. We aimed to evaluate a possible geometric effect of ablation on mitral valve apparatus.Forty-three consecutive patients who underwent for persistent (maintaining sinus rhythm 6 months their procedure) were examined by serial real-time 3-dimensional transesophageal echocardiography before and...

10.1161/circimaging.119.009317 article EN Circulation Cardiovascular Imaging 2019-10-01

from collapsing homes.The incidence of cardiovascular disease (hypertension, 3 acute myocardial infarction, 4 heart failure, pulmonary thromboembolism [PTE] 5,6 and deep vein thrombosis [DVT], 5 other diseases 3,7-9 ), stroke, respiratory infections 10 increases in evacuees after disasters.These concepts have been comprehensively reviewed. 11The unsanitary environment evacuation centers, sympathetic K umamoto Prefecture Japan was struck by a series earthquakes (2016 Kumamoto 1,2 including...

10.1253/circj.cj-18-1369 article EN Circulation Journal 2019-04-07

Cardiac resynchronization therapy (CRT) is a beneficial strategy to improve severe cardiac dysfunction in patients with congestive heart failure (CHF). The improvement of endothelial function CHF treated CRT reflected the mortality risk reduction. However precise mechanisms relationship between and vascular have not been well discussed.Twenty-two consecutive associated dilated cardiomyopathy [New York Heart Association (NYHA) class 3.3 ± 0.5, left ventricular ejection fraction (LVEF) 24.4...

10.1016/j.jjcc.2011.01.010 article EN publisher-specific-oa Journal of Cardiology 2011-04-18

Calcium channel-dependent tissue has been suggested to be involved in the circuit of verapamil-sensitive atrial tachycardia originating from atrioventricular (AV) node vicinity (V-AT), but little information exists.To examine V-AT, a single extrastimulus was delivered during 10 sites intraatrial septum: earliest activation site; His bundle (HB) 3 arbitrarily divided on AV junction extending HB site coronary sinus ostium (CSOS) (sites S, M, and I); internal-CSOS, inferior-CSOS, superior-CSOS,...

10.1161/circep.109.878678 article EN Circulation Arrhythmia and Electrophysiology 2009-12-05

Background: The precise nature of the upper turnaround part atrioventricular nodal reentrant tachycardia (AVNRT) is not entirely understood. Methods: In nine patients with AVNRT accompanied by variable ventriculoatrial (VA) conduction block, we examined electrophysiologic characteristics its common pathway. Results: Tachycardia was induced atrial burst and/or extrastimulus followed atrial‐His jump, and earliest electrogram observed at His bundle site in all patients. Twelve incidents VA...

10.1111/j.1540-8159.2009.02309.x article EN Pacing and Clinical Electrophysiology 2009-03-23

A 79-year-old woman was admitted with a left femoral neck fracture and she immediately developed circulatory shock. Echocardiography showed markedly enlarged right ventricle (RV) systolic ballooning of the mid-ventricular wall preserved contractility apex. The ventricular (LV) motion normal. Multi-detector-row computed tomography severe congestion contrast media in atrium no forward flow to RV, but pulmonary embolism. She successfully treated percutaneous veno-arterial extracorporeal...

10.2169/internalmedicine.8323-16 article EN Internal Medicine 2017-01-01

Little information exists regarding the precise distribution of verapamil-sensitive atrial tachycardia originating from vicinity atrioventricular node (V-AT).In 12 patients with V-AT, we examined spatial and topologic origin relative to His bundle (HB) site. The V-AT was divided into six areas: anterior (A-HB), posterior (P-HB), superior (S-HB), inferior (I-HB), lateral (L-HB), septal (SP-HB) portion HB catheter. Three dimensional distance between distal pair electrodes catheter that (DIS)...

10.1111/j.1540-8159.2007.00900.x article EN Pacing and Clinical Electrophysiology 2007-12-01

Ventricular tachycardia originating from the right ventricular outflow tract (RVOT) is considered benign, but sometimes it causes polymorphic and fibrillation, resulting in sudden cardiac death. A 58-year-old woman without structural heart disease was admitted for evaluation of recurrent episodes syncope. Surface ECG showed frequent repetitive premature contraction (PVC) RVOT origin. Polymorphic triggered by same PVC documented Holter during an episode Radiofrequency catheter ablation...

10.2169/internalmedicine.47.1211 article EN other-oa Internal Medicine 2008-01-01

The incidence and mechanism of the dislocated antegrade fast pathway (A-FP) were examined in various forms atrioventricular nodal reentrant tachycardia (AVNRT).To localize A-FP, 5 atrial sites comprising inferior coronary sinus ostium (CSOS), apex triangle Koch (A-TOK), 3 equidistant on junction extending from A-TOK to CSOS (site S, M, I) pace mapped at 100 beats/min 71 patients with slow-fast (n=49), fast-slow (n=7) slow-intermediate (n=15) AVNRT. site shortest interval between stimulus His...

10.1253/circj.71.1099 article EN Circulation Journal 2007-01-01

Little is known about the effect of nifekalant, a pure I(Kr) -selective blocker, on typical atrial flutter (AFL) and its termination mechanism.The effects nifekalant AFL were elucidated in 17 patients. During AFL, conduction time from lateral to septal cavotricuspid isthmus (IS) that through reminder right atrium (nIS); AFL-cycle length (CL) variability, which was quantified by standard deviation; maximum difference AFL-CL measured before after administration (0.2-0.3 mg/kg). A single...

10.1111/pace.12147 article EN Pacing and Clinical Electrophysiology 2013-04-22

Purpose: We sought to determine if direct flow acquired via endovascular therapy (EVT) reduces major adverse limb events (MALE) rates including amputation (MA), or any re-intervention death for critical ischemia (CLI) patients utilizing the angiosome concept and it improves skin perfusion pressure (SPP). Method: The 51 consecutive study subjects presented 62 limbs ischemic ulceration (Rutherford 5 6) from January 2011 December 2012 in our institution. investigated SPP MALE these CLI treated...

10.1093/eurheartj/eht307.p375 article EN European Heart Journal 2013-08-02

A 15-year-old boy without structural heart disease was admitted for the treatment of frequent episodes premature ventricular contractions (PVCs). Left mapping revealed that origin PVC at posterior papillary muscle. Diastolic small potentials were observed during sinus rhythm with a constant interval following QRS beats. This potential eventually coupled myocardium, resulting in generation PVC, and thus preceded by 31 msec. Catheter ablation to this site induced non-sustained tachycardia,...

10.2169/internalmedicine.49.3618 article EN other-oa Internal Medicine 2010-01-01

Abstract Cavotricuspid isthmus (CTI) ablation is an important treatment strategy for CTI-dependent atrial flutter (AFL). The location of the catheter contact area confirmed by vector direction (CVD) through three-dimensional mapping during procedure. However, relationship between CVD radiofrequency and its efficacy in achieving CTI block has not been clarified. This study aimed to investigate block. CVDs were divided into proximal vectors against distal tip (P-vector) other (normal-vector)....

10.1038/s41598-023-29738-y article EN cc-by Scientific Reports 2023-02-13

The essential boundaries in typical atrial flutter (AF) are unknown.To examine the role of tricuspid annulus (TA) and posterolateral line block (LB) maintaining AF, single extrastimuli were delivered during AF both around LB TA 29 patients. Single from superior, middle, inferior third anterior LB, posterior lateral, inferior, septal portions TA. longest coupling interval (LCI) that reset subsequent return cycle (RC) analyzed.The resetting response showed two patterns (groups 1 2)....

10.1111/j.1540-8159.2007.00673.x article EN Pacing and Clinical Electrophysiology 2007-03-01
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