A5080757815- Ubiquitin and proteasome pathways
- Peptidase Inhibition and Analysis
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Chromatography in Natural Products
- Biological Stains and Phytochemicals
- Bioactive Compounds and Antitumor Agents
- Cancer Genomics and Diagnostics
- Bioinformatics and Genomic Networks
- Phytochemical Studies and Bioactivities
- Machine Learning in Bioinformatics
- Endoplasmic Reticulum Stress and Disease
- Cancer-related molecular mechanisms research
- Histone Deacetylase Inhibitors Research
- Traditional Chinese Medicine Analysis
- Phytochemistry and biological activity of medicinal plants
Hangzhou Women’s Hospital
2023-2024
Hangzhou Hospital of Traditional Chinese Medicine
2019
The Third Affiliated Hospital of Zhejiang Chinese Medical University
2016
Background: Ovarian cancer stands as the deadliest malignant tumor within female reproductive tract. As a result of absence effective diagnostic and monitoring markers, 75% ovarian cases are diagnosed at late stage, leading to mere 50% survival rate five years. The advancement molecular biology is essential for accurate diagnosis treatment cancer. Methods: A review several randomized clinical trials, focusing on cancer, was undertaken. methods related were examined. Results: Liquid biopsy an...
Abstract Emodin, a major component of rhubarb, has anti-tumor effects in variety cancers, influencing multiple steps tumor development through modulating several signaling pathways. The aim this study is to examine the effect emodin on cell apoptosis and explore underlying mechanisms human endometrial cancer cells. Here we report that can inhibit KLE proliferation induce time- dose-dependent manner. Western blot assay found was involved MAPK PI3K/Akt Specifically, significantly suppressed...
<title>Abstract</title> <bold>Background</bold>: Ubiquitin and ubiquitin-like (UUL) modifications play pleiotropic functions are subject to fine regulatory mechanisms frequently altered in cancer. However, the comprehensive impact of UUL modification on breast cancer remains unclear. <bold>Methods</bold>: Transcriptomic clinical data were downloaded from TCGA GEO databases. Molecular subtyping was conducted using NMF CIBERSORT algorithms. Prognostic genes identified via univariate, lasso...
Abstract Background : Ubiquitin and ubiquitin-like (UUL) modifications play pleiotropic functions are subject to fine regulatory mechanisms frequently altered in cancer. However, the comprehensive impact of UUL modification on breast cancer remains unclear. Methods Transcriptomic clinical data were downloaded from TCGA GEO databases. Molecular subtyping was conducted using NMF CIBERSORT algorithms. Prognostic genes identified via univariate, lasso multivariate Cox regression analyses....
Background: Ubiquitin and ubiquitin-like (UUL) modifications play pleiotropic functions are subject to fine regulatory mechanisms frequently altered in cancer. However, the comprehensive impact of UUL modification on breast cancer remains unclear. Methods: Transcriptomic clinical data were downloaded from TCGA GEO databases. Molecular subtyping was conducted using NMF CIBERSORT algorithms. Prognostic genes identified via univariate, lasso multivariate Cox regression analyses. Clinical...