A5101891871- Reconstructive Surgery and Microvascular Techniques
- Diabetic Foot Ulcer Assessment and Management
- Bone fractures and treatments
- Immune Cell Function and Interaction
- Inhalation and Respiratory Drug Delivery
- Biochemical effects in animals
- Traditional Chinese Medicine Analysis
- Liver Disease Diagnosis and Treatment
- Peripheral Artery Disease Management
- Tendon Structure and Treatment
- Nuclear Receptors and Signaling
- Remote-Sensing Image Classification
- Trauma Management and Diagnosis
- Organ Transplantation Techniques and Outcomes
- Cardiovascular Disease and Adiposity
- Spinal Cord Injury Research
- Pelvic floor disorders treatments
- Pressure Ulcer Prevention and Management
- Advanced Image and Video Retrieval Techniques
- Esophageal Cancer Research and Treatment
- PARP inhibition in cancer therapy
- Liver physiology and pathology
- Blood groups and transfusion
- Cancer Treatment and Pharmacology
- Cancer-related molecular mechanisms research
Shanghai Changzheng Hospital
2024
Fujian Medical University
2023
Lanzhou University
2019
The Fifth People's Hospital of Anyang
2018
People's Liberation Army 401 Hospital
2018
Wuhan Polytechnic University
2015
Institute of Zoology
2014
Chinese Academy of Sciences
2014
Soochow University
2010
Abstract Nickel oxide nanoparticles (Nano NiO) bears hepatotoxicity, while whether it leads to liver fibrosis remains unclear. The aim of this study was establish the Nano NiO‐induced hepatic model in vivo and investigate roles transforming growth factor β1 (TGF‐β1) Smad pathway activation, epithelial‐mesenchymal transition (EMT) occurrence, extracellular matrix (ECM) deposition vitro. Male Wistar rats were exposed 0.015, 0.06, 0.24 mg/kg NiO by intratracheal instilling twice a week for 9...
Matrix Metalloproteinase-26 (MMP-26) is the smallest member of matrix metalloproteinase (MMP) family that functions mainly in extracellular milieu to cleave proteins. It expressed various cell types placenta, but its function placentation has been poorly understood. Considering existence a unique cysteine switch sequence MMP-26 protein sequence, as well evidence cancer cells indicating digestion NH2-terminal domain ERβ by MMP-26, we hypothesize may have specific intracellular activity human...
The skin, being the largest organ in human body, plays a vital role shielding internal organs from external physical and chemical factors. However, skin damage caused by various factors such as injuries, surgeries, diabetes, or burns can lead to wounds that diminish skin's protective function. Monitoring essential physiological parameters like temperature, moisture, pH is crucial facilitate antibiotic treatment, remote physician monitoring, patient comfort, cost reduction, prevention of...
Abstract Antibody-drug conjugates (ADCs) are emerging therapeutic agents for targeted cancer treatment with remarkable clinical success. However, tumor heterogeneity and microenvironment complexity still the major factors contributing to drug resistance, recurrence, metastasis, which cannot be resolved a mono therapy strategy. We’ve developed novel dual ADC (BiADC), BR113, by conjugating an anti-hTrop2 antibody linker of Topoisomerase I inhibitor payload, another immune stimulator. Our...
Objective To investigate the effects of hyperbaric oxygen (HBO) therapy following spinal cord injury (SCI) and its mechanisms. Methods Thirty Sprague-Dawley rats were randomly divided into two groups after inducing SCI models using a modified version Allen's method. The HBO group received treatment 2 h procedure then treated 100 min every day for 5 consecutive days. All evaluated 1 before operation, h, 10 d 20 afterward BBB scores inclined plane experiments. Superoxide dismutase (SOD)...
Objective To analyze the effect of thoracoscopic surgery on thoracic esophageal cancer and complications lymph node dissection. Methods Seventy patients with were selected. According to different surgical methods, divided into two groups: 35 who underwent right open thoracotomy selected as control group, whereas other had treated study group. The clinical effects, dissection compared between groups. Results The intraoperative blood loss total amount postoperative chest drainage...
Objective To investigate whether brachial-ankle pulse wave velocity (baPWV), independently and jointly with the level of body mass index (BMI), affect risk incident diabetes hypertension. Methods The effects baPWV BMI on hypertension were evaluated using Kaplan-Meier curves (log-rank test) multi logistical regression models after adjustment for various confounding factors. Results A total 2 222 participants recruited in this study. Higher (Q4) was associated a greater...
Objective To investigate the effect of micro steel plate internal fixation combined with traditional Chinese medicine medicated bath in treatment proximal phalanx fractures. Methods From January 2012 to December 2012, 100 patients fracture Ningbo Mingzhou Hospital were selected and randomly divided into control group observation group, according digital table, 50 cases each group.The was treated by simple miniature fixation, microplate bath.The clinical compared between two...
This study was to explore the denoising and segmentation effect of dual-domain image (DDID) algorithm, Galois field (GF) nonlocal means (NLM) algorithms were introduced for comparative analysis. 40 primiparas in hospital from January 2018 2020 divided into an experimental group (caesarean section (CS), E) a control (vaginal delivery (VD), C). The peak signal-to-noise ratio (PSNR) parameters DDID algorithm compared with GF NLM algorithm. It found that showed higher overall accuracy (OA) lower...