Guangfei Ou

ORCID: 0009-0006-5211-444X
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Cancer, Hypoxia, and Metabolism
  • Effects of Radiation Exposure
  • Lung Cancer Research Studies
  • Nanoplatforms for cancer theranostics
  • Salivary Gland Disorders and Functions
  • Fibroblast Growth Factor Research
  • Angiogenesis and VEGF in Cancer
  • Insect Pest Control Strategies
  • Research on scale insects
  • Brain Metastases and Treatment
  • Cassava research and cyanide
  • Oral health in cancer treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Kruppel-like factors research
  • Head and Neck Cancer Studies
  • Glioma Diagnosis and Treatment
  • Nematode management and characterization studies
  • Myasthenia Gravis and Thymoma
  • Advanced Radiotherapy Techniques
  • Cancer Cells and Metastasis
  • Radiopharmaceutical Chemistry and Applications
  • Pituitary Gland Disorders and Treatments
  • Hepatocellular Carcinoma Treatment and Prognosis

Guangxi University
2025

Guiyang Medical University
2025

Chinese PLA General Hospital
2015

Chinese Academy of Medical Sciences & Peking Union Medical College
2001-2012

Kyoto University
2008-2012

Academia Sinica
2010

Cancer Hospital of Chinese Academy of Medical Sciences
2006

Tumour recurrence frequently occurs after radiotherapy, but the characteristics, intratumoural localization and post-irradiation behaviour of radioresistant cancer cells remain largely unknown. Here we develop a sophisticated strategy to track fate cells, which exist in perinecrotic regions at time radiation. Although tumour are originally hypoxia-inducible factor 1 (HIF-1)-negative, they acquire HIF-1 activity surviving radiation, triggers their translocation towards blood vessels....

10.1038/ncomms1786 article EN cc-by-nc-sa Nature Communications 2012-04-17

For patients with resected pathological stage IIIA-N2 non-small cell lung cancer (NSCLC), the role of postoperative radiotherapy (PORT) is not well defined. In this single-institutional study, we re-evaluated effect PORT on overall survival (OS) as tumor control in subgroup patients.In 2003-2005, 221 consecutive NSCLC at our institution were retrospectively analyzed an institutional review board-approved study. The OS, cancer-specific (CSS), and disease-free (DFS) was evaluated using...

10.1634/theoncologist.2010-0343 article EN The Oncologist 2011-04-11

Background: Sorafenib is a first-line treatment option for patients with hepatocellular carcinoma (HCC). However, the impact of sorafenib resistance type on patient survival prediction and choice second-line regimen unknown. Objectives: This study aims to explore factors predicting in HCC receiving sorafenib, survival, optimal regimen. Design: was retrospective cohort study. Methods: We recruited all advanced who received from January 2019 2023 two medical centers China. They were divided...

10.1177/17588359241299678 article EN cc-by-nc Therapeutic Advances in Medical Oncology 2025-01-01

Abstract As a starch and biofuel feedstock in China, cassava ( Manihot esculenta Crantz) is continuously cultivated on marginal land the south, predominantly red yellow soil types. With prolonged application of conventional tillage (CT) method (mouldboard ploughing once at depth 30–35 cm then raked twice 18 cm), became increasingly compact, while yield decreased year after year. The previous study reported that was significantly increased by Fenlong (FL) tillage, which implements use spiral...

10.1111/sum.70025 article EN Soil Use and Management 2025-01-01

The therapeutic effect of concurrent chemoradiotherapy with TS-1 has been confirmed in various solid tumors; however, the detailed mechanism action not yet fully elucidated. In present study, we identified hypoxia-inducible factor-1 (HIF-1) as one targets chemoradiotherapy. growth delay assays using a tumor xenograft non-small-cell lung carcinoma, H441, treatment enhanced single gamma-ray radiotherapy (14 Gy) and significantly delayed by 1.58-fold compared to alone (P < 0.01). An optical...

10.1111/j.1349-7006.2008.00943.x article EN other-oa Cancer Science 2008-09-23

Cyclooxygenase-2 (COX-2) plays important roles in the modulation of apoptosis, angiogenesis, immune response, and tumor invasion. Elevated COX-2 expression has been reported to be correlated with reduced survival after radiotherapy. This study examined whether genetic variations gene are associated different inoperable locally advanced non-small cell lung cancer (NSCLC) treated chemoradiotherapy or radiotherapy alone.One hundred thirty-six patients stage IIIA-B NSCLC receiving thoracic...

10.1158/1078-0432.ccr-09-2793 article EN Clinical Cancer Research 2010-03-24

This study proposed to retrospectively analyze the efficacy of radiotherapy on brain/bone metastases in patients with stage IV lung adenocarcinoma and evaluate correlation between overall survival after other factors including metastatic sites EGFR mutation status. 115 Stage admitted our center from March, 2011 December, 2013 were enrolled. They presented no solid organs except bone or brain had received prior treatment. 50 test 32 detected as mutant 18 wild-type. Patients treated 40 Gy...

10.4149/neo_2016_019 article EN Neoplasma 2015-12-07

10.1016/j.ijrobp.2006.07.872 article International Journal of Radiation Oncology*Biology*Physics 2006-10-15

The lung and esophagus are always damaged during radiation on thoracic tumors to a certain extent. This study is report the incidence of pneumonitis esophagitis analyze factors as predictors toxicity in treatment three-dimensional conformal radiotherapy (3DCRT) for cancer.Between March 1999 September 2003, 112 cancer patients treated with 3DCRT were reviewed at this Hospital. population consisted 87 men 25 women, including 97 cases non-small cell 15 small cancer. median age was 64 years old....

10.3779/j.issn.1009-3419.2005.05.22 article EN PubMed 2005-10-20
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