Radmehr Shafiee

ORCID: 0009-0006-9067-0586
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Research Areas
  • Veterinary Oncology Research
  • Infectious Diseases and Mycology
  • Hedgehog Signaling Pathway Studies
  • Microbial infections and disease research
  • Liver Disease Diagnosis and Treatment
  • Lipid metabolism and disorders
  • Veterinary Medicine and Surgery
  • Mast cells and histamine
  • Cancer Research and Treatments
  • Diet, Metabolism, and Disease
  • Cancer Cells and Metastasis
  • Oral and Maxillofacial Pathology
  • Salivary Gland Tumors Diagnosis and Treatment
  • Cancer Diagnosis and Treatment
  • Virus-based gene therapy research
  • Testicular diseases and treatments
  • Molecular Biology Techniques and Applications
  • Xenotransplantation and immune response
  • Urinary Bladder and Prostate Research
  • Coccidia and coccidiosis research
  • Prostate Cancer Diagnosis and Treatment
  • Animal Genetics and Reproduction
  • Adipokines, Inflammation, and Metabolic Diseases
  • Veterinary Equine Medical Research
  • Genital Health and Disease

University of Tehran
2013-2024

Abstract Background The human “Elston and Ellis grading method” was utilized in dogs with mammary tumor to examine its relation prognosis this species, based on a 2-year follow-up period. Although cytopathology is widely used for early diagnosis of neoplasms, it not commonly performed veterinary medicine. Our objectives study were identify criteria malignancy canine tumors the frequency different types lesions their relationship histologic grade investigated. Another aim differentiate simple...

10.1186/1475-2867-13-79 article EN cc-by Cancer Cell International 2013-08-09

The diagnosis of breast lesions is usually confirmed by fine-needle aspiration cytology (FNAC) or histological biopsy. Although there increasing literature regarding the advantages and limitations both modalities, no accuracy these modalities for diagnosing in high-risk patients, who have detected screening. Moreover, few studies been published cytopathology mammary tumors cats despite widespread use animal model cancer formation inhibition. objective present study was to evaluate diagnostic...

10.1186/1746-1596-8-136 article EN cc-by Diagnostic Pathology 2013-08-13

Cutaneous mast cell tumours (MCTs) are the most common skin in dogs. Due to prevalence of canine MCTs and variable biologic behavior this disease, accurate prognostication a thorough understanding MCT biology critical for treatment disease. A cytologic diagnosis tumor with evidence prior hemorrhage was made, masses were surgically removed. Cytological evaluation fine-needle aspirates from cutaneous mass axillary comprised many well-differentiated, highly granulated cells moderate numbers...

10.1186/1746-1596-9-9 article EN cc-by Diagnostic Pathology 2014-01-20

In September 2012, a 10-year-old, intact male, terrier mix breed dog was evaluated because of multiple, 0.5 to 1.2 cm in diameter, round, intradermal nodules around the anus. It had surgery excise firm, painful swelling left ventrolateral perianal region and excision part observed under light microscopy. The mass spreading sub acute hind leg out from ventro-lateral anus, cm×1 cm/ 0 cm×0.5 size 125 g weight. A complete blood cell count, serum biochemistry panel, urinalysis (cystocentesis...

10.1016/s2221-1691(13)60117-3 article EN Asian Pacific Journal of Tropical Biomedicine 2013-06-27

Squamous cell carcinomas (SCCs) are uncommon, high-grade tumors, predominantly composed of round cells in the prepuce. The aim this study is to better define clinicopathologic features neoplasm. We conducted cyto-histopathologic analysis on manifestations prepuce SCC by H & E staining a terrier mix dog. Grossly, tumor was large, multiple erythematous patch, and ulcerated masses frequently affecting deeply invading distal out from ventro-lateral penis covered necrotic discharge. Cytological...

10.1186/1746-1596-9-110 article EN cc-by Diagnostic Pathology 2014-06-06

In this study, the frequency of different types mammary masses and their relationship with cytohistopathologic changes was investigated data on history, macroscopic description, clinical examination treatment were collected. To determine prevalence changes, glands from 12 female cats evaluated. The mean age at time diagnosis 11.5 ± 1.9 years (range 4-14 years), gross size 3.1 2.4 cm, 4/12 (33.3 %) ≤3.0 cm in diameter, maximum diameter largest mass had a median 5 range 6 × 4 cm. Moreover,...

10.1007/s13277-014-2515-7 article EN Tumor Biology 2014-08-20

SUMMARY OBJECTIVES: Nonalcoholic fatty liver disease is the term used for a range of conditions in which fat builds up and exceeds 5% hepatocytes without inordinate alcohol intake or other causes lipid accumulation. Regarding fact that insulin resistance obesity play key roles pathogenesis nonalcoholic disease, as well connection between resistin these metabolic diseases, association gene (RETN) polymorphism was examined. METHODS: In this genetic case–control study, 150 biopsy-proven...

10.1590/1806-9282.20231537 article EN Revista da Associação Médica Brasileira 2024-01-01

In this study, 12 dogs affected by canine transmissible venereal tumor (CTVT) and testicular seminoma were studied retrospectively. The cytological sample was smeared onto a glass slide either air-dried for May-Grünwald-stain, masses surgically removed. tumors grossly examined, sections of 4-μm thick obtained from each stained with H&E. For chemotherapy, vincristine sulfate administered weekly as an infusion over 3 min via the cephalic vein at dose 0.025 mg/kg after diluting physiological...

10.1007/s13277-014-1723-5 article EN Tumor Biology 2014-02-20

The aim of this study was to evaluate the prevalence acute and chronic inflammation, benign prostatic hyperplasia (BPH), cancer prostate glands in canine as a human model disorders. carried out on 12 cases different male dogs terrier (50 %), German shepherd (25 %) breeds, Greden age ranged from 6 13 years (average 7.8 ± 3.6). bodyweight 3.6 7.9 kg. Signalment, clinical signs, diagnostic tools such ultrasonography, urinary cytology, histopathology are presented. Dysuria most common sign...

10.1007/s13277-014-2854-4 article EN Tumor Biology 2014-11-25

The aim of this study was to evaluate the prevalence acute and chronic inflammation, benign prostatic hyperplasia (BPH), cancer prostate glands in canine as a human model disorders. carried out on 12 cases different male dogs terrier (50 %), German shepherd (25 %) breeds, Greden age ranged from 6 13 years (average 7.8 ± 3.6). bodyweight 3.6 7.9 kg. Signalment, clinical signs, diagnostic tools such ultrasonography, urinary cytology, histopathology are presented. Dysuria most common sign...

10.1007/s13277-016-5475-2 article EN Tumor Biology 2016-11-08

A 9-year-old emasculated male Spitz with tenesmus and constipation had a subcutaneous mass at the left ventral aspect of anus history polyuria polydipsia. complete blood cell count, serum biochemistry panel, urinalysis (cystocentesis sample) were evaluated. Abnormalities in panel included mildly elevated cholesterol concentration (7.28 mmol/L; reference interval, 2.70-5.94 mmol/L), increased alkaline phosphatase activity (184 U/L; 9-90 U/L), alanine transaminase (122 5-60 U/L) aspartate...

10.1016/s2221-1691(13)60027-1 article EN Asian Pacific Journal of Tropical Biomedicine 2013-01-01

This article has been retracted at the request of Editor-in- Chief, International Society Oncology and BioMarkers (ISOBM) Publisher per Committee on Publication Ethics guidelines. The shows evidence irregularities in authorship during submission process, there is strong reason to believe that peer review process was compromised contains patchwork plagiarism from a variety sources. main sources are (amongst others): Bruce E. LeRoya, icole Northrup, Prostate cancer dogs: Comparative clinical...

10.1007/s13277-014-2854-4). article EN 2016-01-01

Abstract Objective Nonalcoholic fatty liver disease (NAFLD), which is an emerging global chronic disease, has a close association with insulin resistance. We aimed to determine whether the Gly1057Asp (rs1805097) polymorphism of receptor substrate 2 (IRS2) gene associated NAFLD. Methods Using polymerase chain reaction-restriction fragment length method, 135 patients biopsy-proven NAFLD and controls underwent IRS2 genotype analysis. Results Genotype allele distributions variant conformed...

10.1093/labmed/lmad066 article EN Laboratory Medicine 2023-07-22
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