- Forensic and Genetic Research
- Forensic Anthropology and Bioarchaeology Studies
- Environmental DNA in Biodiversity Studies
- Molecular Biology Techniques and Applications
- Real-time simulation and control systems
- Gut microbiota and health
- Metabolism and Genetic Disorders
- Smart Grid and Power Systems
- Science Education and Perceptions
- Metabolomics and Mass Spectrometry Studies
- Power Systems and Renewable Energy
- Genetic and phenotypic traits in livestock
Sun Yat-sen University
2023-2025
Inferring relatedness through the detection of identity-by-descent (IBD) segments is widely used in many fields. However, existing methods are often powerless for poor-quality DNA samples. Here, we propose a method, clusIBD, which can robustly detect IBD using unphased genetic data with high genotype errors. We evaluated and compared performance clusIBD IBIS, TRUFFLE, IBDseq simulated data, artificial materials ancient The results showed that outperformed these state-of-the-art tools may be...
Background/Objectives: Kinship inference is commonly adopted in various forensic applications, but previous studies have often lacked precision. Methods: In this study, a new method for the nomenclature of kinship types, i.e., chain (KC), was proposed, and then, six types identity by state (IBS) scores were calculated simulated real families using four markers. Finally, several Bayesian network (BN)-based classifiers constructed to investigate efficiency inference. Results: A total 7, 22,...
Background: Forensic investigative genetic genealogy (FIGG) has developed rapidly in recent years and is considered a novel tool for crime investigation. However, scene samples are often of low quality quantity challenging to analyze. Deciding which approach should be used kinship inference forensic practice remains troubling problem investigators. Methods: In this study, we selected four popular approaches—KING, IBS, TRUFFLE, GERMLINE—comprising one method moment (MoM) estimator three...
Previous studies have explored the improvement in kinship analysis using autosomal markers (e.g., A-STR and A-SNPs), but ignoring value of nonautosomal markers. This study introduced a new method on nomenclature types, i.e., chain (KC), which links sex combinations two questioned individuals all related family members. Then, six kinds identity by state (IBS) scores were calculated for simulated real families autosome, X-chromosome, Y-chromosome, mtDNA. Finally, several Bayesian network...
The inference of body fluids and tissues is critical in reconstructing crime scenes inferring criminal behaviours. Nevertheless, present methods are incompatible with conventional DNA genotyping, additional testing might result excessive consumption forensic scene materials. This study aims to investigate the feasibility distinguishing common fluid/tissues through difference mitochondrial copy number (mtDNAcn). Five different types fluids/tissues were analyzed this - blood, hair, saliva,...
The stable operation of SVG device is closely related to the H-bridge submodules. In electric power industry, standard practice deal with a fault submodule bypass it. However, may become black modules due various reasons, so that their status uncertain and cannot be bypassed. To solve this problem, new cascaded module redundancy scheme proposed in paper, which can rapidly start logic when occurs them accurately. This paper analyzes communication architecture, topology charging discharging...