Lei Zhang

ORCID: 0009-0007-0034-6457
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About
Contact & Profiles
Research Areas
  • Genetic Mapping and Diversity in Plants and Animals
  • Genetic and phenotypic traits in livestock
  • Forensic and Genetic Research
  • Chronic Myeloid Leukemia Treatments
  • Genetics and Plant Breeding
  • Wheat and Barley Genetics and Pathology
  • Acute Myeloid Leukemia Research
  • Animal Behavior and Welfare Studies
  • Genetic diversity and population structure
  • Yersinia bacterium, plague, ectoparasites research
  • Kruppel-like factors research
  • Medicinal Plants and Bioactive Compounds
  • Acute Lymphoblastic Leukemia research
  • Cancer-related molecular mechanisms research

Central Hospital of Putuo District
2024

Shanghai Medical Information Center
2024

Institute of Crop Sciences
2017

Chinese Academy of Agricultural Sciences
2017

Pure lines derived from multiple parents are becoming more important because of the increased genetic diversity, possibility to conduct replicated phenotyping trials in environments and potentially high mapping resolution quantitative trait loci (QTL). In this study, we proposed a new method for QTL detection pure-line populations four-way crosses, which is able control background variation through two-stage strategy. First, orthogonal variables were created each marker used an inclusive...

10.1038/hdy.2017.42 article EN cc-by-nc-nd Heredity 2017-07-19

Background:The incidence of chronic obstructive pulmonary disease (COPD) is increasing year by year.Kruppel-like factor 6 (KLF6) plays an important role in inflammatory diseases.However, the regulatory KLF6 COPD has not been reported so far.Methods: The viability human bronchial epithelial cells BEAS-2B induced cigarette smoke extract (CSE) was detected CCK-8 assay.The protein expression and sirtuin 4 (SIRT4) appraised with Western blot.RT-qPCR blot were applied to examine transfection...

10.2147/copd.s451264 article EN cc-by-nc International Journal of COPD 2024-03-01

Summary Teat number is an extremely valuable trait for sow reproduction performance and piglet survival. Here, we used genotyping‐by‐sequencing a general liner model to carry out genome‐wide analysis of total teat in Erhualian population. The results indicated that eight SNP s on chromosomes 4, 5, 9 10 were significant genome wide (Bonferroni method, P < 2.85E‐7) number. Validation analyses performed 298 904 Large White sows using these the procedure sas . Finally, only chromosome 5 was...

10.1111/age.12547 article EN Animal Genetics 2017-04-03

Acute lymphoblastic leukemia (ALL) is characterized by highly genetic heterogeneity, owing to recurrent fusion genes, gene mutations, intragenic deletion, and overexpression, which poses significant challenges in clinical detection. RNA sequencing (RNA-seq) a powerful tool for detecting multiple abnormalities, especially cryptic rearrangements, single test.

10.1111/ijlh.14269 article EN International Journal of Laboratory Hematology 2024-03-29
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