Giorgia Guccione

ORCID: 0009-0007-0175-8912
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About
Contact & Profiles
Research Areas
  • Sirtuins and Resveratrol in Medicine
  • Synthesis and Characterization of Pyrroles
  • Synthesis and biological activity

University of Genoa
2024

The search and development of effective sirtuin small molecule inhibitors (SIRTIs) continues to draw great attention due their wide range pharmacological applications. Based on SIRTs’ involvement in different biological pathways, ligands were investigated for many diseases, such as cancer, neurodegenerative disorders, diabetes, cardiovascular diseases autoimmune diseases. elucidation a substantial number SIRT2–ligand complexes is steering the identification novel more selective modulators....

10.3390/ijms252011084 article EN International Journal of Molecular Sciences 2024-10-15
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