- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
University of Kinshasa
2019-2025
Background: Renal complications of sickle cell disease are becoming very common, and patients generally do not respond to conventional nephroprotective treatments. Among the drugs used, hydroxyurea (HU) seems have produced good results according some studies. This molecule has yet been evaluated in DR Congo for this purpose. To evaluate albuminuria glomerular filtration rate (GFR) after 9 months HU treatment a population children with incipient nephropathy. Methods: was an open clinical...
Background: Sickle cell anemia is the most common genetic disease in sub-Saharan Africa. It an inherited autosomal recessive disorder characterized by chronic hemolysis secondary to falciformation of red blood cells, also responsible ischemia, bone infarction and accompanied serious infections organic lesions.Normal for weight at birth, subjects have low pre puberty growth compared normal children compromised remodeling balance which results decrease mass increase fragility. Several studies...