A5065043177- Circadian rhythm and melatonin
- Photosynthetic Processes and Mechanisms
- Epigenetics and DNA Methylation
- Algal biology and biofuel production
- Amino Acid Enzymes and Metabolism
- Health, Environment, Cognitive Aging
- Marine and coastal ecosystems
- Biocrusts and Microbial Ecology
- Gut microbiota and health
- Plant and Biological Electrophysiology Studies
- Polyamine Metabolism and Applications
- Protist diversity and phylogeny
- Marine and coastal plant biology
- Light effects on plants
- Microbial Community Ecology and Physiology
- Photoreceptor and optogenetics research
- Dietary Effects on Health
Vanderbilt University
2019-2024
Surely most chronobiologists believe circadian clocks are an adaptation of organisms that enhances fitness, but we certain this focus our research effort really confers a fitness advantage? What is the evidence, and how do evaluate it? best criteria? These questions topic review. In addition, will discuss selective pressures might have led to historical evolution systems while considering intriguing question whether ongoing climate change modulating these so clock still evolving.
Photoperiodic time measurement is the ability of plants and animals to measure differences in day versus night length (photoperiod) use that information anticipate critical seasonal transformations, such as annual temperature cycles. This timekeeping phenomenon triggers adaptive responses higher organisms, gonadal stimulation, flowering, hibernation. Unexpectedly, we observed this capability cyanobacteria—unicellular prokaryotes with generation times short 5 6 hours. Cyanobacteria exposed...
The methyl cycle is a universal metabolic pathway providing groups for the methylation of nuclei acids and proteins, regulating all aspects cellular physiology. We have previously shown that inhibition in mammals strongly affects circadian rhythms. Since clocks evolved early during evolution operate organisms across tree life, we sought to determine whether link between two also conserved. Here, show biological rhythms species ranging from unicellular algae humans, separated by more than 1...
The circadian rhythms of hosts dictate an approximately 24 h transformation in the environment experienced by their gut microbiome. consequences this cyclic on intestinal microbiota are barely understood and likely to have medical ramifications. Can daily rhythmicity act as a selective pressure that shapes microbial community? Moreover, given several bacterial species been reported exhibit themselves, we test here whether rhythmic is favors clock-harboring bacteria can anticipate prepare for...
An amendment to this paper has been published and can be accessed via a link at the top of paper.
Cyanobacteria are photosynthetic bacteria whose gene expression patterns globally regulated by their circadian (daily) clocks. Due to ability use sunlight as energy source, they also attractive hosts for “green” production of pharmaceuticals, renewable fuels, and chemicals. However, despite the application traditional genetic tools such identification strong promoters enhance heterologous genes, cyanobacteria have lagged behind other microorganisms Escherichia coli yeast economically...
Abstract Photoperiodic Time Measurement is the ability of plants and animals to measure differences in day/night-length (photoperiod) use that information anticipate critical seasonal transformations such as annual temperature cycles. This timekeeping phenomenon triggers adaptive responses higher organisms gonadal growth/regression, flowering, hibernation. Unexpectedly, we discovered this capability cyanobacteria, unicellular prokaryotes with generation times only 5-6 h. Cyanobacteria short...
Abstract The methyl cycle is a universally conserved metabolic pathway operating in prokaryotes and eukaryotes. In this pathway, the amino acid methionine used to synthesize S-adenosylmethionine, donor co-substrate methylation of nucleic acids, histone non-histone proteins many other molecules within cell. acids foundation epigenetic epitranscriptomic regulations gene expression, but whether centrally regulates expression function by controlling availability moieties poorly understood. From...