A5103198304- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Otolaryngology and Infectious Diseases
- Ion Transport and Channel Regulation
- Cancer Immunotherapy and Biomarkers
- Pneumonia and Respiratory Infections
- Economic and Financial Impacts of Cancer
- Infective Endocarditis Diagnosis and Management
- Immune Cell Function and Interaction
- Diabetes Treatment and Management
- CAR-T cell therapy research
- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Helicobacter pylori-related gastroenterology studies
Jackson Laboratory
2024
Indiana University School of Medicine
2013
Indiana University – Purdue University Indianapolis
2013
The University of Texas Health Science Center at Houston
2011
Myocarditis has emerged as an immune-related adverse event of immune checkpoint inhibitor (ICI) cancer therapy associated with significant mortality. To ensure patients continue to safely benefit from life-saving therapy, understanding fundamental immunological phenomena underlying ICI myocarditis is essential. We recently developed the NOD-cMHCI/II-/-.DQ8 mouse model that spontaneously develops lower mortality than observed in previous HLA-DQ8 NOD strains. Our strain was rendered murine MHC...
Guidelines currently provide conflicting recommendations regarding the diagnosis of group A streptococcal (GAS) pharyngitis in adults. Clinical guidelines state that negative rapid antigen detection tests (RADTs) do not require confirmation by a backup method adults, whereas laboratory-based mandate RADT patients all ages. The objective this study was to assess utility reflexive culture following adolescents and adults with suspected GAS pharyngitis.A retrospective analysis 726 patients,...
<i>Objective:</i> Tuberculosis has a staggering influence on world health, resulting in nearly 2 million deaths per year. The of glucocorticoids during <i>Mycobacterium tuberculosis</i> infection been under investigation for decades; however, the identity mycobacterial factors and mechanism by which are tissue specifically regulated to immune function acute granuloma formation unknown. <i>Methods:</i> One factor implicated initiating immunopathology...