I. Lerouge

ORCID: 0009-0007-1061-6334
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About
Contact & Profiles
Research Areas
  • Legume Nitrogen Fixing Symbiosis
  • Ethics in Clinical Research
  • Wastewater Treatment and Nitrogen Removal
  • Plant nutrient uptake and metabolism
  • Artificial Intelligence in Healthcare and Education
  • Bacteriophages and microbial interactions
  • Machine Learning in Bioinformatics
  • Plant Pathogenic Bacteria Studies
  • Cancer Research and Treatments
  • Escherichia coli research studies
  • Infant Nutrition and Health
  • Academic integrity and plagiarism
  • Pediatric Hepatobiliary Diseases and Treatments

KU Leuven
1999-2024

Janssen (Belgium)
1998

This document presents the Bonn PRINTEGER Consensus Statement: Working with Research Integrity—Guidance for research performing organisations. The aim of statement is to complement existing instruments by focusing specifically on institutional responsibilities strengthening integrity. It takes into account daily challenges and organisational contexts most researchers. intends make integrity recognisable from work-floor perspective, providing concrete advice measures strengthen statement,...

10.1007/s11948-018-0034-4 article EN cc-by Science and Engineering Ethics 2018-05-31

Researchers of KU Leuven, a large Belgian university, were invited to complete bespoke questionnaire assessing their attitudes toward research integrity and the local culture, with specific emphasis on supervision junior researchers. A total 7,353 invitations sent via e-mail 1,866 responses collected (25.3% response rate), which 1,723 are reported upon here. Some findings relevant broader community. Whereas supervisors evaluated researchers almost unanimously as positive, fewer supervisees...

10.1080/08989621.2024.2318245 article EN Accountability in Research 2024-02-19

For O-antigen lipopolysaccharide (LPS) synthesis in bacteria, transmembrane migration of undecaprenyl pyrophosphate-bound oligosaccharide subunits or polysaccharide occurs before ligation to the core region LPS molecule. In this study, we identified by mutagenesis an ATP-binding cassette transporter Rhizobium etli CE3 that is likely responsible for translocation across inner plasma membrane. Mutant FAJ1200 lacks largely O-antigen, as shown SDS-polyacrylamide gel electrophoresis and confirmed...

10.1074/jbc.m101129200 article EN cc-by Journal of Biological Chemistry 2001-05-01

The Bradyrhizobium japonicum hupT gene was sequenced, and its product found to be homologous NtrB-like histidine kinases. A mutant expresses higher levels of hydrogenase activity than the wild-type strain under hydrogenase-inducing conditions (i.e., microaerobiosis plus hydrogen, or symbiosis), whereas in noninduced cells, hupSL expression is derepressed but does not lead activity. We conclude that HupT involved repression HupSL synthesis at transcriptional level enzymatic activation...

10.1128/jb.181.16.5085-5089.1999 article EN Journal of Bacteriology 1999-08-15

The elucidation of the structure O-antigen Rhizo-bium etli CE3 predicts that R. genome must contain genes encoding acetyl- and methyltransferases to confer corresponding modifications O-antigen. We identified three open reading frames (ORFs) upstream wzm, membrane component transporter located in lpsα-region CE3. ORFs encode two putative acetyltransferases with similarity CysE-LacA-LpxA-NodL family acetyl-transferases one methyltransferase sequence motifs common a wide range...

10.1094/mpmi.2003.16.12.1085 article EN other-oa Molecular Plant-Microbe Interactions 2003-12-01
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