G. Paparella

ORCID: 0009-0007-2103-4276
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About
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Research Areas
  • Cardiac Arrhythmias and Treatments
  • Cardiac pacing and defibrillation studies
  • Atrial Fibrillation Management and Outcomes
  • Neurological disorders and treatments
  • Cardiac electrophysiology and arrhythmias
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Migraine and Headache Studies
  • Parkinson's Disease Mechanisms and Treatments
  • Musculoskeletal pain and rehabilitation
  • Cardiac Valve Diseases and Treatments
  • Heart Rate Variability and Autonomic Control
  • Cardiac Structural Anomalies and Repair
  • Electrospun Nanofibers in Biomedical Applications
  • Cardiomyopathy and Myosin Studies
  • Gastrointestinal disorders and treatments
  • Vascular anomalies and interventions
  • Infrared Thermography in Medicine
  • Congenital Heart Disease Studies
  • Aortic Disease and Treatment Approaches
  • Infective Endocarditis Diagnosis and Management
  • Neurological Disorders and Treatments
  • Mesenchymal stem cell research
  • Effects of Vibration on Health
  • Pulmonary Hypertension Research and Treatments
  • Pancreatitis Pathology and Treatment

University of Bari Aldo Moro
2024-2025

Agostino Gemelli University Polyclinic
2019

KLE Society Hospital
2018

Sir Ganga Ram Hospital
2018

Clinique Saint Jean
2015

Universitair Ziekenhuis Brussel
2010-2014

Clinique Saint Pierre
2013-2014

Vrije Universiteit Brussel
2008

Ospedale di San Donà di Piave
2003

Ospedale Santa Maria della Misericordia di Udine
2002

The novel cryoballoon Advance (CB-A) has proven to achieve significantly lower temperatures and faster pulmonary vein isolation (PVI) times in comparison with the first-generation device. Although acutely very effective, best of our knowledge, data on mid-term clinical follow-up is lacking.The aim study was analyse freedom from recurrence atrial fibrillation (AF) a 1-year period, series consecutive patients having undergone PVI CB-A for paroxysmal AF (PAF).Forty-two [30 male (71%); mean age:...

10.1093/europace/eut417 article EN EP Europace 2014-01-28

Atrial fibrillation (AF) ablation is increasingly being performed in electrophysiology laboratories. Pericardial effusion (PE) certainly one of the most frequently observed complications during AF ablation. The aim our study was to investigate incidence and outcome PE following cryothermal energy balloon (CBA) comparison with conventional circumferential pulmonary vein isolation a focal radiofrequency (RF) catheter.A total 133 consecutive patients (105 males) paroxysmal were included this...

10.1093/europace/eup422 article EN EP Europace 2010-01-06

Background: Heart rate variability (HRV) provides both linear and nonlinear autonomic proxies that can be informative of health status in fibromyalgia (FM), where sympatho-vagal abnormalities are common. This retrospective observational study aims to: 1. detect differences correlation dimension (D2) between FM patients healthy controls (HCs); 2. correlate D2 with standard HRV parameters; 3. the degree changes using a global composite parameter called grade, derived from three indices (SDNN =...

10.3390/s25082618 article EN cc-by Sensors 2025-04-21

Transseptal (TS) puncture during atrial fibrillation (AF) ablation is a relatively safe procedure in experienced hands. However, major and minor complications cannot be completely ruled out. Real-time three-dimensional transeosophageal echocardiography (RT 3D TEE) novel imaging technology that permits direct visualization of the fossa ovalis perspective, thereby sensibly lowering likelihood potential adverse effects TS. In our study, we describe technique assess feasibility, advantages,...

10.1093/europace/eun275 article EN EP Europace 2008-08-15

AimsAlthough it has been shown that a transseptal (TS) puncture in the electrophysiology laboratory is associated with high success and low complication rate, this procedure remains challenging particularly difficult septum anatomies (aneurismal thick septum) during repeat TS catheterization. Radiofrequency (RF) electrocautery current delivery through needle to facilitate puncture. The aim of study was verify prospectively feasibility, safety, outcome RF energy standard technique patients undergoing

10.1093/europace/euq019 article EN EP Europace 2010-02-23

A 37-year-old male suffering from recurrent symptomatic atrial fibrillation was referred for pulmonary vein (PV) isolation.Pulmonary isolation attempted using a cryoablation approach (Arctic Front Advance w cryoballoon and ACHIEVE Mapping Catheter , Medtronic Ablation Frontiers LLC).During PV catheterization, the distal part of catheter stuck in branch right superior PV.After rotational manoeuvres to dislodge catheter, tip fractured at junction his straight circular remained entrapped...

10.1093/europace/eut352 article EN EP Europace 2013-11-26

We describe a case of 50-year-old man with advanced atrioventricular block treated successfully His-bundle pacing via persistent left superior vena cava draining into the coronary sinus.

10.1093/europace/eun170 article EN EP Europace 2008-06-17

Background: Migraine is a painful neurological condition affecting emotional, cognitive, and daily life functioning. Cognitive reserve (CR) protective factor against damage deterioration, but its proxies have been under-investigated in migraine. The present crosssectional study aims to investigate the relationship between CR several self-reported health measures migraine; how these differ grades. Methods: Data were collected from an Italian tertiary center 2022 2023. One hundred eighty...

10.4081/cc.2024.15769 article EN cc-by-nc Confinia Cephalalgica 2024-06-18

Plasma neurofilament light chain (NFL) has been measured as a biomarker of neuronal damage in various neurological disorders. Elevated tau and β-amyloid levels have found patients with fibromyalgia (FM). The aim the present study was to compare plasma normal controls investigate correlation clinical features cognitive tests.

10.1002/ejp.4752 article EN European Journal of Pain 2024-11-04

Background:The possibility of culturing heart cells in order to regenerate damaged tissue is a challenging problem.Recent observations have demonstrated the isolating and expanding resident cardiac stem cells, which could favor regeneration functional improvement myocardial tissue. Aims:To investigate two different media: one promoting c-kit cells' growth other differentiation muscle cells. Methods:We obtained primary cultures from left ventricle tissues 10 human hearts patients with...

10.17352/2455-2976.000013 article EN cc-by-nc Journal of Cardiovascular Medicine and Cardiology 2015-03-07

Patients with permanent right ventricular apical pacing may develop interventricular and intraventricular dyssynchrony as a consequence of the pacing-induced "LBBB-like" activation. Aim study: to compare effects cardiac resynchronization therapy (CRT) in pts spontaneous LBBB PILBBB.

10.1016/j.eupc.2005.08.188 article EN EP Europace 2005-10-01

Purpose of study was to analyse safety and long-term efficacy endoscopic treatment in children with CP.

10.1055/s-0039-1681578 article EN Endoscopy 2019-03-18

L.4 New Technologies allows both retrograde venogram and lead insertion.In 33 (77%) pts the CS was successfully approached directly by CLVS, in attempt to reduce implantation time.The mean X-ray exposition time 19±9 min.The distal CLVS placed a posterolateral branch 19 pts, posterior 2, lateral 21, anterior 1.The threshold of LVP value at 1.1±0.9V.A significant reduction.17.

10.1016/eupace/4.supplement_1.a29-a article EN EP Europace 2003-10-01

The programmed ventricular sensitivity at discharge was = 3 mV in all Pts independently of the LV signal and none them reported any complication FU (range: 3-12 months).Conclusions: occurrence oversensing is not rare Biv stimulation if a high programmed.A safe reliable programming stimulator possible by considering only RV sensing level. RESYNCHRONIZATION THERAPY AND ATRIAL FIBRILLATION18.

10.1016/eupace/4.supplement_1.a30-b article EN EP Europace 2003-10-01

When evaluating the clinical impact of cardiac resynchronisation therapy (CRT), it is paramount importance to ascertain potential for significant reduction in morbidity and mortality.Also importance, total cost treatment patient with severe congestive heart failure (NYHA 3-4).To look at this question, we used a mathematic model after obtaining costs optimal pharmacologic therapy, medical care, laboratory diagnostic tests hospitalization complications from centers across Canada.We identified...

10.1016/eupace/4.supplement_1.a27-b article EN EP Europace 2003-10-01

Five patients were considered as non responders to biventricular pacing.Five died during the follow-up: 2 (1 for refractory HF and 1 cancer) 3 sudden death; renal failure).A significative reduction of mean furosemide dose per day (-56.2mg) was observed follow-up.Conclusions: in our experience CRT improved cardiac function with beneficial impact on reverse remodelling cardiovascular events.This effect evident both pts sinus rhythm atrial fibrillation.Further investigations a better...

10.1016/eupace/4.supplement_1.a28-c article EN EP Europace 2003-10-01
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