- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- ECG Monitoring and Analysis
- Ion channel regulation and function
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Imaging and Diagnostics
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- COVID-19 Clinical Research Studies
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Cardiovascular and Diving-Related Complications
- Respiratory Support and Mechanisms
- Pericarditis and Cardiac Tamponade
- Receptor Mechanisms and Signaling
- Long-Term Effects of COVID-19
- Botulinum Toxin and Related Neurological Disorders
- Neuroscience and Neural Engineering
Universitair Ziekenhuis Brussel
2009-2025
Vrije Universiteit Brussel
2010-2025
Centre Hospitalier de Mouscron
2021-2024
Epicura
2020-2023
Ingegneria dei Sistemi (Italy)
2023
Intel (United States)
2023
Fundación Juan March
2010-2023
Maria Cecilia Hospital
2023
Institute of Applied Science and Intelligent Systems
2022
Cleveland Clinic
2015-2021
With the increasing interest in conduction system pacing (CSP) over last few years and inclusion of this treatment modality current guidelines, our aim was to provide a snapshot practice across Europe. An online questionnaire sent physicians participating European Heart Rhythm Association research network as well national societies social media. Data on previous experience with CSP, indications, preferred tools, unmet needs, perceptions for future are reported discussed.
Abstract Aims Pulsed field ablation (PFA) has emerged as a novel, non-thermal energy source to selectively ablate cardiac tissue. We describe multicentre experience on pulmonary vein isolation (PVI) via the pentaspline Farapulse™ PFA system vs. thermal-based technologies in propensity score-matched population of paroxysmal atrial fibrillation (PAF) patients. Methods and results Propensity score matching was adopted compare PVI-only outcomes Farawave™ (Group PFA), cryoballoon CRYO), or focal...
Abstract Aims The multielectrode radiofrequency balloon catheter (RFB) has been developed to achieve safe and effective pulmonary vein isolation (PVI) for atrial fibrillation (AF) ablation. This single-centre study aimed evaluate the midterm clinical outcome predictors of single-shot PVI with novel RFB. Methods results All consecutive patients symptomatic paroxysmal or persistent AF undergoing first-time RFB were prospectively included. Clinical procedural parameters systematically...
A pathogenic/likely pathogenic variant can be found in 20% to 25% of patients with Brugada syndrome (BrS) and a SCN5A is associated worse prognosis. The aim this study define the diagnostic yield large gene panel American College Medical Genetics Genomics classification assess prognosis non-SCN5A variants.
Functional mitral regurgitation (MR) could be managed by both cardiac resynchronization therapy (CRT) and mitral-valve surgery. Clinical decision making regarding the appropriateness of surgery vs. CRT is a challenging task. This study assessed prevalence prognosis various degrees functional MR in candidates. Additionally, we sought to identify patients who either can adequately only or will need Cardiac recipients (n= 794) were followed-up for 26 ± 18 months. Mitral severity was quantified...
AimsNo specific data are available on the influence of pulmonary vein (PV) anatomy and shape cryoballoon ablation (CA) catheter efficacy in delivering cryothermal energy and, consequently, obtaining PV isolation.
We sought to investigate the value of a family history sudden death (SD) in Brugada syndrome (BS). Two hundred and eighty consecutive patients (mean age: 41 ± 18 years, 168 males) with diagnostic type I ECG pattern were included. Sudden occurred 69 (43%) 157 families. One ten SDs analysed. During follow-up VF (ventricular fibrillation) or SD-free survival rate was not different between without SD first-degree relative, multiple relative at any age relatives ≤35 years. patient had two years...
Abstract Background and Aims Pulmonary vein isolation (PVI) is the most effective rhythm control strategy in paroxysmal atrial fibrillation (AF). Pulsed field ablation (PFA) has emerged as a novel, non-thermal energy source to selectively ablate cardiac tissue. We report first multicenter experience on PVI via pentaspline FarapulseTM PFA system versus thermal-based technologies propensity score-matched population of AF patients. Methods Propensity score matching was adopted compare PVI-only...
Objectives: Assess the predictive accuracy of WHO COVID-19 severity classification on hospitalized patients. The secondary aim was to compare its power with a new prediction model, named EPI-SCORE, based Bayesian network analysis. Methods: We retrospectively analyzed population 295 RT-PCR positive patients at Epicura Hospital Center, Belgium, admitted between March 1st and April 30th, 2020. Results: Our cohort’s median age 73 (62–83) years, female proportion 43%. All were classified...
Hybrid atrial fibrillation (AF) ablation is a promising approach in non-paroxysmal AF. The aim of this study to assess the long-term outcomes hybrid large cohort patients after both an initial and as redo procedure.All consecutive undergoing AF at UZ Brussel from 2010 2020 were retrospectively evaluated. was performed one-step procedure: (i) thoracoscopic followed by (ii) endocardial mapping eventual ablation. All received PVI posterior wall isolation. Additional lesions based on clinical...
BACKGROUND: Pulsed field ablation (PFA) is a novel technology for catheter-based atrial arrhythmia treatment. Evidence of its application ventricular still limited. In this study, we describe the feasibility and efficacy focal PFA premature contraction (PVC) ablation. METHODS: A prospective cohort 20 patients referred PVC at 2 centers was enrolled, regardless presence structural heart disease, morphology, or previous attempts. All procedures were performed using CENTAURI System in...
Atrial fibrillation (AF) ablation is increasingly being performed in electrophysiology laboratories. Pericardial effusion (PE) certainly one of the most frequently observed complications during AF ablation. The aim our study was to investigate incidence and outcome PE following cryothermal energy balloon (CBA) comparison with conventional circumferential pulmonary vein isolation a focal radiofrequency (RF) catheter.A total 133 consecutive patients (105 males) paroxysmal were included this...
Abstract Conventional stylet‐driven leads with extendable helix can be implanted successfully for left bundle branch area pacing (LBBAP) a low acute complication rate. We report two cases in which lead repositioning after first unsuccessful attempt to LBBAP was associated fracture of the rotating mechanism and failure fully extract lead.
Abstract Introduction Pulmonary vein isolation (PVI) with thermal energy is characterized by concomitant ablation of the surrounding ganglionated plexi (GP). Pulsed‐field (PFA) selectively targets myocardium and seems associated only negligible effects on autonomic nervous system (ANS). However, little known about dynamic PFA GP immediately after PVI. This study sought to investigate degree acute vagal modulation induced Farapulse TM during PVI compared single‐shot ablation. Methods A total...
Cryoballoon (CB) ablation is the mainstay of single-shot pulmonary vein isolation (PVI). A radiofrequency balloon (RFB) catheter has recently emerged as an alternative. However, these two technologies have not been compared. This study aims to evaluate freedom from atrial tachyarrhythmias (ATas) at 1 year: procedural characteristics, efficacy, and safety novel RFB compared with CB for PVI in patients paroxysmal fibrillation (AF).This prospective multi-centre included consecutive symptomatic...
Abstract Aims Atrial fibrillation (AF) and chronic kidney disease (CKD) often coexist share an increased risk of thrombo-embolism (TE). CKD concomitantly predisposes towards a pro-haemorrhagic state. Our aim was to evaluate the prognostic value in patients undergoing percutaneous left atrial appendage occlusion (LAAO). Methods results A total 2124 consecutive AF LAAO were categorized into stage 1+2 (n = 1089), 3 796), 4 170), 5 69) based on estimated glomerular filtration rate at baseline....