A5100758626- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cardiac pacing and defibrillation studies
- Occupational and environmental lung diseases
- Cardiac electrophysiology and arrhythmias
- Medical Imaging and Pathology Studies
- Tracheal and airway disorders
- Vascular Anomalies and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Venous Thromboembolism Diagnosis and Management
- Systemic Sclerosis and Related Diseases
- Cardiovascular and Diving-Related Complications
- Infectious Diseases and Tuberculosis
- Urological Disorders and Treatments
- Cardiac tumors and thrombi
- Liver Disease Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Central Venous Catheters and Hemodialysis
- Cardiac Imaging and Diagnostics
- Hernia repair and management
- Orthopedic Infections and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Occupational exposure and asthma
- Sarcoidosis and Beryllium Toxicity Research
University Hospital Schleswig-Holstein
2019-2025
University of Lübeck
2019-2025
Zentralklinik Bad Berka
2024-2025
Hôpital Louis Pradel
2014-2023
Université Claude Bernard Lyon 1
2014-2023
Universitäres Kinderwunschzentrum Lübeck
2021-2022
German Centre for Cardiovascular Research
2019-2021
Hospices Civils de Lyon
2014-2020
Cleveland Clinic
2018
Leo Pharma (Denmark)
2018
Abstract Aims Oesophageal fistula represents a rare but dreadful complication of atrial fibrillation catheter ablation. Data on its incidence, management, and outcome are sparse. Methods results This international multicentre registry investigates the characteristics oesophageal fistulae after treatment by A total 553 729 ablation procedures (radiofrequency: 62.9%, cryoballoon: 36.2%, other modalities: 0.9%) were performed, at 214 centres in 35 countries. In 78 138 patients [0.025%,...
Abstract Background Left atrial appendage closure (LAAC) has emerged as an alternative to oral anticoagulation (OAC) for stroke prevention in patients with fibrillation (AF). OAC treatment been proven feasible mild‐to‐moderate chronic kidney disease (CKD). In contrast, the optimal antithrombotic management of AF end‐stage renal (ESRD) is unknown and LAAC not these prospective randomized clinical trials. Objectives The objective this study evaluate safety efficacy ESRD. Methods Patients...
BACKGROUND: Pulsed field ablation (PFA) is a novel technology for catheter-based atrial arrhythmia treatment. Evidence of its application ventricular still limited. In this study, we describe the feasibility and efficacy focal PFA premature contraction (PVC) ablation. METHODS: A prospective cohort 20 patients referred PVC at 2 centers was enrolled, regardless presence structural heart disease, morphology, or previous attempts. All procedures were performed using CENTAURI System in...
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Managing atrial fibrillation in kidney transplant patients poses a challenge for both nephrologists and cardiologists. Data regarding the safety efficacy of catheter ablation this patient's cohort is scarce. In two-center prospective study, we included all consecutive who underwent between April 2017 March 2022. A 1:3 propensity score matching created control group non-transplant AF undergoing ablation. We 16 48 matched controls. Ablation was successful patients. The periprocedural...
Abstract Background Ablation of ventricular tachycardia is still challenging and has limited efficacy with the traditional thermal energy. Next to its rapidly expanding application in atrial fibrillation (AF) ablation, pulsed field ablation (PFA) may also offer advantages arrhythmias. Methods We conducted a prospective case series involving 5 male patients (mean age: 68±11.5 years) ischemic cardiomyopathy (ICM) referred for monomorphic (MMVT), one patient had VT storm despite therapy...
Abstract Background Radiofrequency ablation of outflow (OT) premature ventricular contractions (PVC) is well established and showed satisfactory acute success with reasonable long term recurrence rates. There little data regarding PVCs using pulsed field energy. Due to increased transmurality, (PFA) may have an advantage in cases mid- epimyocardial origins, yet proximity the coronary arteries increase risk PFA related vasospasms. Objective To assess safety efficacy focal for OT Methods A...
Abstract Introduction In some cases of atrioventricular nodal reentrant tachycardia (AVNRT), ablation the slow pathway (SP) at inferoseptal right-atrium may be ineffective. Some alternative sites for can present distinct challenges and potential complications (e.g. risk [AV] block with closer to AV node, ineffective energy delivery due high impedance vessel damage in coronary sinus [CS]). Methods: We conducted a retrospective analysis AVNRT performed our center between January 2010 September...
Abstract Aims Cryoballoon (CB) based pulmonary vein isolation (PVI) is a widely used technique for treatment of atrial fibrillation (AF); however the ideal energy dosing has not yet been standardized. This was single-centre randomized clinical trial aiming at assessing safety, acute efficacy, and outcome an individualized vs. fixed CB ablation protocol using fourth-generation (CB4) guided by (PV) potential recordings temperature. Methods results Patients were in 1:1 fashion to two different...
Introduction: A growing body of evidence suggests a strong association between atrial fibrillation (AF) and cancer. relevant number patients with present or former malignant disease highly symptomatic drug-refractory AF are in need interventional therapy. Data on the safety efficacy catheter ablation these sparse. The study aims to analyze cryoballoon-based pulmonary vein isolation (CB-PVI) for past cancer disease. Methods Results: Consecutive undergoing CB-PVI at University Hospital Lübeck,...
Data reporting a head-to-head comparison between Amulet and Watchman devices are scarce. The aim of this study was to compare the Watchman™ versus Amulet™ left atrial appendage closure (LAAC) in consecutive, industry-independent registry.Patients who underwent LAAC using or from January 2014 December 2019 at University Heart Center Lübeck, Germany were included present analysis. Primary endpoints periprocedural complications (in-hospital death, pericardial tamponade, device embolization,...
We sought to assess the efficacy, safety and short-term clinical outcome of very high-power short-duration (vHP-SD) radiofrequency (RF) catheter ablation for treatment idiopathic PVCs originating from cardiac outflow tract (OT).
Patients with heart failure and severe mitral regurgitation (MR) have a poor prognosis carry an increased risk for ventricular arrhythmias. The present study evaluates the impact of transcatheter valve repair using MitraClip on potential reduction arrhythmias.Patients undergoing implantation were prospectively enrolled into received 24 h Holter ECG assessment prior to 6 months after procedure. In addition, left dimensions function assessed at baseline follow-up. A total 50 patients mainly...
Left atrial appendage (LAA) electrical isolation (LAAEI) in addition to pulmonary vein is an emerging catheter-based therapy treat symptomatic fibrillation. Previous studies found high incidences of LAA thrombus formation after LAAEI. This study sought analyse therapeutic strategies aiming at the resolution thrombi and prevention thromboembolism.Left was conducted via creation left linear lesions or cryoballoon ablation. Follow-up including transoesophageal echocardiography conducted. In...
To evaluate outcomes of percutaneous left atrial appendage closure (LAAC) in patients with congestive heart failure (CHF) and non-valvular fibrillation (AF) a consecutive, industry-independent registry associated periprocedural success complications during long-term follow-up.For this analysis, we included who underwent transcatheter LAAC from January 2014 to December 2019 at the University Heart Center Lübeck, Germany, compared presence CHF defined as reduced ventricular ejection fraction...
ABSTRACT Introduction In patients with atrial arrhythmias originating from the superior vena cava (SVC), use of radiofrequency energy to isolate SVC is associated a significant risk injury both phrenic nerve and sinus node. Pulsed field ablation (PFA) may overcome disadvantages thermal improve efficacy safety. Objective We report feasibility, safety, clinical focal monopolar PFA in origin their arrhythmia SVC. Methods Nine (7 men, age 66 ± 8 years) SVC‐induced paroxysmal AF ( n = 3),...
Abstract Purpose Studies on predictive scores for very late recurrence (VLR) (recurrence later than 12 months) after second-generation cryoballoon-based pulmonary vein isolation (CB2-PVI) are sparse. We aimed to evaluate the frequency of (LR) (later 3 and VLR, validate LR VLR initial CB2-PVI. Methods A total 288 patients undergoing CB2-PVI (66 ± 11 years, 46% paroxysmal) were retrospectively enrolled in cohort. In cohort, 83 with within 3–12 months or < 12-month follow-up excluded. The...
BACKGROUND:Despite use of optimal oral anticoagulation regimens, left atrial appendage (LAA) thrombus may develop and persist in patients with fibrillation (AF). The therapeutic options this population are limited. Percutaneous LAA closure (LAAC) is performed to reduce formation the risk thromboembolism. However, approach prohibited thrombus. We report case a 76-year-old man AF persistent who underwent percutaneous LAAC LAmbre device protected by SENTINEL Cerebral Protection System (CPS)....
Abstract Objectives To compare the Watchman™ versus Amulet™ left atrial appendage closure (LAAC) devices in a consecutive, industry-independent registry. Background Data reporting head-to-head comparison between Amulet and Watchman are scarce. Methods Patients who underwent LAAC using or from January 2014 to December 2019 at University Heart Center Lübeck, Germany were included present analysis. Primary endpoints periprocedural complications (in-hospital death, pericardial tamponade, device...