A5006329290- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Lipoproteins and Cardiovascular Health
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Antiplatelet Therapy and Cardiovascular Diseases
- Vascular Procedures and Complications
- Infective Endocarditis Diagnosis and Management
- Cardiac Health and Mental Health
- Venous Thromboembolism Diagnosis and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular and Diving-Related Complications
- Cardiac pacing and defibrillation studies
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Risk Factors
- Health Promotion and Cardiovascular Prevention
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes Treatment and Management
- Long-Term Effects of COVID-19
Assiut University
2014-2025
Leeds Teaching Hospitals NHS Trust
2022
University of Leeds
2021-2022
European Society of Cardiology
2022
Assiut University Hospitals
2007-2021
Cairo University
2019
Hôpital Européen Georges-Pompidou
2019
Ospedale San Luigi Gonzaga
2018
GTx (United States)
2011
Leiden University Medical Center
2009
The aim of this study was to determine whether the Joint European Societies guidelines on secondary cardiovascular prevention are followed in everyday practice.A cross-sectional ESC-EORP survey (EUROASPIRE V) at 131 centres 81 regions 27 countries.Patients (<80 years old) with verified coronary artery events or interventions were interviewed and examined ≥6 months later.A total 8261 patients (females 26%) interviewed. Nineteen per cent smoked 55% them persistent smokers, 38% obese (body mass...
The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge evidence available at time their publication.The is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...
Background: Valvular heart disease (VHD) is an important cause of mortality and morbidity has been subject to changes in management. The VHD II survey was designed by the EURObservational Research Programme European Society Cardiology analyze actual management compare practice with guidelines. Methods: Patients severe native or previous valvular intervention were enrolled prospectively across 28 countries over a 3-month period 2017. Indications for considered concordant if performed...
European Action on Secondary and Primary Prevention by Intervention to Reduce Events (EUROASPIRE) V in primary care was carried out the Society of Cardiology EURObservational Research Programme 2016-2018. The main objective determine whether 2016 Joint Societies' guidelines cardiovascular disease prevention people at high risk have been implemented clinical practice.The method used a cross-sectional survey 78 centres from 16 countries. Patients without history atherosclerotic either started...
INTERASPIRE is an international study of coronary heart disease (CHD) patients, designed to measure if guideline standards for secondary prevention and cardiac rehabilitation are being achieved in a timely manner. Between 2020 2023, adults hospitalized the preceding 6-24 months with incident or recurrent CHD were sampled 14 countries from all 6 World Health Organization regions invited standardized interview examination. Direct age sex standardization was used country-level prevalence...
The association of adipocyte-derived proteins, adiponectin and leptin, with the degree coronary atherosclerosis has not been well elucidated. This study aimed to determine relationship between serum leptin presence atherosclerosis.Seventy patients 20 matched controls were recruited. Angiographic evaluation was carried out by assessing three atherosclerotic indices, severity (transverse disease), extent (longitudinal pattern (lesion complexity).The independent predictors larger waist/hip...
Carvedilol is a novel β-adrenoreceptor blocker, with antioxidant properties inhibiting lipid peroxidation and preventing the depletion of endogenous antioxidants. Moreover, carvedilol was reported to enhance expression Bcl-2 gene, which has antiapoptotic effects. There are few researches testing protective effect on development diabetic cardiomyopathy nephropathy. In this study, we induced diabetes mellitus in male Wistar albino rats. We investigated carvedilol, as well vitamin E,...
This study was performed to assess the incidence, patient characteristics and predictors of aborted myocardial infarction (MI) in patients with ST-segment elevation MI (STEMI) undergoing primary percutaneous coronary intervention (PPCI).We enrolled 179 consecutive STEMI within a fixed protocol for PPCI (Leiden MISSION! project); 90 received abciximab bolus hospital (in-hospital group) 89 ambulance (pre-hospital group). Thirty-two (18%) fulfilled criteria an MI. The incidence four times...
We investigated the incidence of radial anomalies (RA) in patients undergoing transradial (TR) coronary procedure and their impact on procedural outcome Egyptian population. Radial are considered an important factor for failure. Information about anatomical variation is limited our performed a multicentre prospective study Egypt. A total 650 consecutive first TR were recruited from January 2013 till 2015. By retrograde arteriography we assessed frequency RA outcome. studied, 74% male, mean...
PTMC produces significant changes in mitral valve morphology as improvement leaflets mobility. The determinants of such have not been assessed before.The study included 291 symptomatic patients with stenosis undergoing PTMC. Post-PTMC subvalvular splitting area was a determinant post-PTMC excursion both the anterior (B 0.16, 95% CI 0.03 to 0.30, p < 0.05) and posterior 0.12, 0.01 0.24, leaflets. Another transmitral pressure gradient for -0.02, -0.04 -0.005, 0.01) -0.01, excursion....
Optical coherence tomography (OCT) provides valuable information to guide percutaneous coronary intervention (PCI) in acute syndrome (ACS) regarding lesion preparation, stent sizing, and optimization. The aim of the present study was compare lumen expansion stent-treated lesions immediately after procedure for ACS between OCT-guided PCI angiography-guided PCI.
To evaluate outcomes of percutaneous left atrial appendage closure (LAAC) in patients with congestive heart failure (CHF) and non-valvular fibrillation (AF) a consecutive, industry-independent registry associated periprocedural success complications during long-term follow-up.For this analysis, we included who underwent transcatheter LAAC from January 2014 to December 2019 at the University Heart Center Lübeck, Germany, compared presence CHF defined as reduced ventricular ejection fraction...
This prospective cross-sectional observational study aimed at reporting the demographics of ACS patients admitted to Assiut University Hospital, Egypt, and validating both TIMI (Thrombolysis in Myocardial Infarction) GRACE (Global Registry Acute Coronary Events) scores prediction in-hospital MACE 30-day mortality recurrent MI ST-elevation myocardial infarction (STEMI) unstable angina/non-ST-elevation (UA/NSTEMI) patients. Data were collected from all over one year April 1, 2011. The included...
Markers of platelet activity (P-selectin), fibrinolysis (d-dimer), thrombin (prothrombin fragments 1, 2 [PF1,2] and thrombin–antithrombin III complex [TAT]), inflammation (interleukin 1β [IL-1β]) were measured in 65 patients with mitral stenosis (MS) before weeks after percutaneous valvotomy (PMV) 23 controls. All markers significantly higher than the control decreased PMV. P-selectin change correlated changes left atrial diameter (LAD), pulmonary artery systolic pressure (PASP), IL-1β....
Background: The benefits of early abciximab administration and thrombus aspiration in ST elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) have previously been elaborated. However, whether there is an adjunctive effect among STEMI patients, with angiographic evidence thrombus, receiving prehospital remains unclear. Methods: In the context a fixed protocol for PPCI, 158 consecutive were enrolled, whom was started before hospital...
This study was performed to evaluate the feasibility and safety of early sheath removal after percutaneous coronary intervention (PCI) using a locally designed Assiut Femoral Compression Device (AFCD2) vs. manual compression (MC). Due antithrombotic therapy before, during, PCI, arterial femoral is generally not removed PCI. randomized, controlled trial. We enrolled all patients undergoing PCI at University Hospitals from September, 2013 December, 2013. At end hemostasis method randomly...
After successful pulmonary vein isolation (PVI) for atrial fibrillation (AF), the left atrium (LA) undergoes reverse remodeling. However, few studies have directly studied (PV) remodeling and focused on whether pre PVI-PV conditions could predict outcome of procedure. We hypothesize that: (I) post PVI, in addition to LA PVs undergo a parallel degree remodeling; (II) that PV characteristics PVI can be used identify patients more likely sustain normal sinus rhythm (NSR).Patients (n=100)...
Abstract Background Deferred stenting, despite being successful in early studies, showed no benefit recent trials. However, these trials were testing routine deferral; not patients with heavy thrombus burden. Results This is a prospective, Randomized Clinical Trial that included 150 who presented STEMI, allocated into three equal groups after the coronary angiography ± primary intervention and before stenting of culprit lesion; group (A) 50 deferral (B) late (C) immediate stenting. No-reflow...