- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac pacing and defibrillation studies
- Heart Rate Variability and Autonomic Control
- ECG Monitoring and Analysis
- Venous Thromboembolism Diagnosis and Management
- Plant Reproductive Biology
- Cardiovascular Effects of Exercise
- Plant pathogens and resistance mechanisms
- Ion channel regulation and function
- Aging, Health, and Disability
- Medical research and treatments
- Refrigeration and Air Conditioning Technologies
- Botulinum Toxin and Related Neurological Disorders
- Sleep and Work-Related Fatigue
- Cardiac Structural Anomalies and Repair
- Health and Lifestyle Studies
Vrije Universiteit Brussel
2018-2023
Universitair Ziekenhuis Brussel
2018-2022
Instituto Dante Pazzanese de Cardiologia
2020
Maria Cecilia Hospital
2019
Beneficência Portuguesa de São Paulo
2014
Background: Several disorders present reflex or persistent increase in vagal tone that may cause refractory symptoms even a normal heart patient. Cardioneuroablation, the denervation by radiofrequency ablation of neuromyocardial interface, was developed to treat these conditions without pacemaker implantation. A theoretical limitation could be reinnervation, naturally grows first year, recover hyperactivity. This study aims verify degree chronic phase after cardioneuroablation. Additionally,...
Abstract Background Cardioneuroablation (CNA) is a novel therapeutic approach for functional bradyarrhythmias, specifically neurocardiogenic syncope or atrial fibrillation, achieved through endocardial radiofrequency catheter ablation of vagal innervation, obviating the need pacemaker implantation. Originating in nineties, first series CNA procedures was published 2005. Extra‐cardiac stimulation (ECVS) employed as direct method stepwise denervation control during CNA. Objective This study...
Vagal hyperactivity is directly related to several clinical conditions as reflex/functional bradyarrhythmias and vagal atrial fibrillation (AF). Cardioneuroablation provides therapeutic denervation through endocardial radiofrequency ablation for these cases. The main challenges are neuromyocardium interface identification the control validation. finding that AF-Nest (AFN) eliminates atropine response decreases RR variability suggests they innervation.Prospective, controlled, longitudinal,...
Background The rate of sudden cardiac death (SCD) in Brugada syndrome (BrS) is ≈1%/y. Noninvasive electrocardiographic imaging a noninvasive mapping system that has role assessing BrS depolarization and repolarization abnormalities. This study aimed to analyze parameters during ajmaline test (AJT). Methods Results All consecutive epicardial maps the right ventricle outflow tract (RVOT-EPI) with CardioInsight were retrospectively analyzed. (1) RVOT-EPI activation time (RVOT-AT); (2) recovery...
Left atrial posterior wall isolation (LAPWI) is often performed in addition to pulmonary vein (PVI) the setting of persistent fibrillation (AF) ablation. The aim this study was evaluate feasibility and safety a new cryoballoon ablation system achieving PVI + LAPWI isolation.The prospective, non-randomized, single center study. Forty consecutive patients, undergoing with novel POLARx™, were compared 40 patients who underwent same procedure established Arctic Front Advance PRO™.Acute achieved...
Paroxysmal atrial fibrillation (PAF) can be triggered by non-pulmonary vein foci, like the superior vena cava (SVC). The latter is correlated with improved result in terms of freedom from tachycardias (ATs), when electrical isolation this vessel utilizing radiofrequency energy (RF) achieved.Evaluate clinical impact, patients PAF, SVC (SVCi) addition to ordinary pulmonary (PVI) means second-generation cryoballoon (CB) METHODS: A total 100 consecutive that underwent CB ablation for PAF were...
Pulmonary vein (PV) isolation is an established treatment for paroxysmal drug-refractory atrial fibrillation (AF). High parasympathetic tone and reconnection of PVs have demonstrated to be possible culprits AF recurrence after ablation. Our aim was investigate the association between reconnected in patients with AF.Consecutive who underwent a redo catheter ablation procedure tachyarrhythmia by means 3D electroanatomic mapping documentation presence or absence following initial cryoballoon...
The aim of this study is to assess specific per-vein procedural predictors pulmonary vein (PV) late reconnection in cryoballoon ablation (CbA) METHODS AND RESULTS: We enrolled 148 consecutive patients undergoing a redo procedure after previous index CbA our center. A at least one PV was found 80 (54.1%) and the most frequently reconnected right inferior (RIPV). Overall, (PVr) associated with longer time -40°C (Tt-40°C) (54.4 ± 21.7 vs 67.6 27.6 seconds; P < .001), warmer nadir temperature...
Abstract Background A left common pulmonary vein (LCPV) accounts as the most frequent (PV) variation. Our aim was to compare performance of radiofrequency (RF) versus second‐generation cryoballoon (CB‐A) ablation in patients with atrial fibrillation (AF) and LCPVs. Methods In a total cohort 716 undergoing PV isolation preprocedural CT‐scanning, LCPV+ were selected measurement ostial area trunk distance. All matched between RF CB‐A group 1:1 ratio based on propensity scores, compared for...
Abstract Purpose The purpose of this study was to evaluate the safety and feasibility new high-resolution mapping algorithm SuperMap (Acutus Medical, CA, USA) in identifying guiding ablation setting regular atrial tachycardias following index fibrillation (AF) ablation. Methods Seven consecutive patients who underwent a radiofrequency catheter guided by novel noncontact charge density (CD) for tachycardia were prospectively enrolled our study. Results Arrhythmogenic substrate identified all...