Sisi Xie

ORCID: 0009-0007-2369-6046
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About
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Research Areas
  • Virus-based gene therapy research
  • Diabetes and associated disorders
  • RNA Interference and Gene Delivery
  • CRISPR and Genetic Engineering
  • Pluripotent Stem Cells Research
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Viral-associated cancers and disorders
  • Mycorrhizal Fungi and Plant Interactions
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Quantum Mechanics and Applications
  • RNA and protein synthesis mechanisms
  • Heat shock proteins research
  • Immune cells in cancer
  • RNA Research and Splicing
  • Phagocytosis and Immune Regulation
  • Animal Genetics and Reproduction
  • Quantum Computing Algorithms and Architecture
  • Xenotransplantation and immune response
  • Plant biochemistry and biosynthesis
  • Plant Pathogens and Fungal Diseases
  • Quantum Information and Cryptography
  • Pancreatic function and diabetes
  • Immunotherapy and Immune Responses

Beijing Electronic Science and Technology Institute
2025

Zhejiang University-University of Edinburgh Institute
2023-2024

Guangxi Normal University
2024

Peking University
2003-2006

Background Epstein-Barr virus (EBV) is a double-stranded DNA oncogenic virus. Several types of solid tumors, such as nasopharyngeal carcinoma, EBV-associated gastric and lymphoepithelioma-like carcinoma the lung, have been linked to EBV infection. Currently, several TCR-T-cell therapies for tumors are in clinical trials, but due suppressive immune microenvironment application therapy limited. Figuring out mechanism by which participates formation tumor immunosuppressive will help T cells or...

10.1136/jitc-2023-008375 article EN cc-by-nc Journal for ImmunoTherapy of Cancer 2024-06-01

Yellow Camellia (Camellia sect. chrysantha) is a rare ornamental plant and an important germplasm resource globally. nitidissima thrives in normal acidic soils, while limonia can adapt to the calcareous soils found karst areas. Our previous study on adaptation of yellow camellias revealed that expression levels heat shock protein 20(HSP20) were higher than nitidissima. However, functions HSP20 gene remain unclear data. In this study, genes (ClHSP20-OE lines) Camellia. (CnHSP20-OE cloned...

10.1186/s12870-023-04686-x article EN cc-by BMC Plant Biology 2024-01-02

Abstract Primordial germ cells (PGCs) are the precursors of germline that specified at embryonic stage. Recent studies reveal humans employ different mechanisms for PGC specification compared with model organisms such as mice. Moreover, specific regulatory machinery is still largely unexplored, mainly due to inaccessible nature this complex biological process. Here, we collect and integrate multi-omics data, including 581 RNA-seq, 54 ATAC-seq, 45 ChIP-seq, 69 single-cell RNA-seq samples from...

10.1101/2024.01.03.574034 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-01-03

SUMMARY Processing bodies (P-bodies) are the membraneless organelles that play critical roles in RNA storage and decay. Abnormalities P-bodies contribute to diseases developmental disorders. Huge efforts have been applied identification of protein components P-bodies, however, dynamics human embryonic stem cells (hESCs) during maintenance differentiation remain largely elusive. Here, we characterized profiles from HEK293T cells, hESCs, hESC-derived mesodermal cells. The number decreases upon...

10.1101/2023.11.22.568232 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-11-22

Lactarius hatsudake is a common ectomycorrhizal edible mushroom in Pinus massoniana forests, and has important ecological potential economic values. However, there are only few reports on the establishment of massoniana–Lactarius symbiosis. Here, we isolated new strain L. (GX01) from local masson pine forest established its symbiosis with P. massoniana. Potato dextrose agar (PDA) medium was optimal for growth GX01. The saffron-to-brown ectomycorrhiza formed by GX01 usually bifurcated or...

10.3390/f15040578 article EN Forests 2024-03-22
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