A5017870615- Catalytic C–H Functionalization Methods
- Fluorine in Organic Chemistry
- Chemical Synthesis and Analysis
- Radical Photochemical Reactions
- Click Chemistry and Applications
- Chemical Synthesis and Reactions
- Oxidative Organic Chemistry Reactions
- Catalytic Cross-Coupling Reactions
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Sulfur-Based Synthesis Techniques
- Synthesis and Biological Evaluation
- Synthetic Organic Chemistry Methods
- Synthesis and Catalytic Reactions
- Cyclopropane Reaction Mechanisms
- Asymmetric Synthesis and Catalysis
- Vanadium and Halogenation Chemistry
- Carbohydrate Chemistry and Synthesis
- Innovative Microfluidic and Catalytic Techniques Innovation
- Multicomponent Synthesis of Heterocycles
- Organoboron and organosilicon chemistry
Anhui Polytechnic University
2015-2023
Nanjing University of Science and Technology
2010-2014
Commercially available CF2Br2 has been used as a convenient source for the rapid and reliable incorporation of gem-difluorovinyl motif into an allene framework via N-heterocyclic carbene catalyzed difluoroolefination 1,3-enynes. The reaction proceeds through cascade three-component radical relay/elimination process. This protocol is distinguished by its mild conditions, readily accessible starting materials, wide substrate scope, ease late-stage functionalization, thus unlocking...
An unprecedented organocatalytic asymmetric construction of novel six-membered carbocycle fused uracils has been demonstrated by the reaction remotely enolizable 6-methyluracil-5-carbaldehydes with 2-bromoenals. The involves an N-heterocyclic carbene-catalyzed formal [4 + 2] annulation o-quinodimethane (oQDM) dienolates α,β-unsaturated acylazoliums, followed a cascade lactone formation/decarboxylation process. This protocol unlocks new platform to access enantioenriched carbocycle-fused uracils.
Abstract Di‐ tert ‐butyl peroxide can smoothly promote the coupling of aryl halides with benzene derivatives without aid transition‐metal catalysts through a chain homolytic aromatic substitution mechanism in presence potassium ‐butoxide.
A fluorous hydrazine-carbothioate organocatalyst was prepared. Together with NCS, the catalyst showed a good activity in acetalization of aldehydes and alcohols. It could be recovered from reaction mixture by solid-phase extraction (F-SPE) excellent purity for direct reuse.
An enantioselective construction of spirocyclic ketones bearing the gem -difluoromethylene group has been accomplished through NHC-catalyzed umpolung [3 + 2] annulation enals with cyclic -difluoroalkyl ketones.
In this study, we present a straightforward and highly effective photo-triggered hydrogenation method for aryl halides, devoid of transition-metal catalysts. Through the synergistic utilization light, PhNHNH2, base, have successfully initiated desired radical-mediated process. Remarkably, utilizing mild reaction conditions, wide range including fluorides, chlorides, bromides, iodides, can be selectively transformed into their corresponding (hetero)arene counterparts, with exceptional yields....
A novel fluorous hydrazine‐1,2‐bis(carbothioate) was prepared. It showed good catalytic activity in the synthesis of ꞵ‐chloroethers with N‐chlorosuccinimide under mild reaction conditions. This organocatalyst could be recovered and recycled several times purity.
A fluorous hydrazinecarbothioate organocatalyst was prepared. Together with orthoformate, the catalyst showed a good activity for acid-free acetalization of aldehydes and alcohols. The cat...
An eco-friendly protocol for C–X bond reduction using visible light, eliminating the need transition metals and performed in air.
Abstract Fluoroalkylated 1,4‐disubstituted [1,2,3]‐triazoles are shown to be good catalysts for the aldol condensation of aldehydes and ketones.
Alcohols represent versatile structural motifs in the fields of fine chemicals, agrochemicals, and pharmaceuticals. In field green chemistry, pursuit increasingly eco-friendly economically viable methods for transforming aldehydes ketones into alcohols holds paramount importance. this research, we introduce a novel approach that directly light-inducedly facilitates reduction alcohols. This method employs isopropanol as both reaction solvent reducing agent, presence t-BuOK. operationally...