- Process Optimization and Integration
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Geochemistry and Elemental Analysis
- SARS-CoV-2 and COVID-19 Research
- Advanced Control Systems Optimization
- Information and Cyber Security
- Long-Term Effects of COVID-19
- Network Security and Intrusion Detection
- COVID-19 Clinical Research Studies
- HIV/AIDS Research and Interventions
- Cryptography and Data Security
- Advanced Malware Detection Techniques
- Catalysis for Biomass Conversion
- Blockchain Technology Applications and Security
- Geological and Geophysical Studies Worldwide
- Water Resources and Management
- Security and Verification in Computing
- Vaccine Coverage and Hesitancy
- Topic Modeling
- HIV/AIDS drug development and treatment
- Natural Language Processing Techniques
- Hearing, Cochlea, Tinnitus, Genetics
- HIV Research and Treatment
- Infectious Diseases and Tuberculosis
Loyola University Chicago
2024
Laboratoire d’Études en Géophysique et Océanographie Spatiales
2020-2023
Institut de Recherche pour le Développement
2022
Université de Toulouse
2020-2022
Regeneron (United States)
2021-2022
Temple University
2022
Centre National de la Recherche Scientifique
2022
Université Toulouse III - Paul Sabatier
2022
Vietnam National University Ho Chi Minh City
2020-2022
Vietnam Academy of Science and Technology
2022
Gonadotropin-inhibitory hormone (GnIH) is a hypothalamic neuropeptide that modulates the reproductive physiology of birds and mammals by inhibiting gonadotropin secretion from anterior pituitary gland. GnIH can also directly inhibit behaviors, possibly via action within brain. Identification distribution neurons fibers may provide us with clues to how brain controls activities animal. Here, we characterized location connectivity in rhesus macaque (Macaca mulatta) We determined precursor...
Abstract Recently, there has been a growing interest in the development of cost‐effective technologies for production biofuels. A common approach to biofuel research is invent or improve biochemical thermochemical conversion step. Subsequently, other and separation steps are added form complete biorefinery flowsheet. Because this structured around specific step, it may limit possibilities configuring optimal innovative biorefineries. This article proposes novel systematic two‐stage synthesis...
Abstract Background The open-label RECOVERY study reported improved survival in hospitalized, SARS-CoV-2 seronegative patients treated with casirivimab and imdevimab (CAS + IMD). Methods In this phase 1/2/3, double-blind, placebo-controlled trial conducted prior to widespread circulation of Delta Omicron, hospitalized COVID-19 were randomized (1:1:1) 2.4 g or 8.0 CAS IMD placebo, characterized at baseline for viral load serostatus. Results total, 1336 on low-flow no supplemental...
The pooling problem is an important optimization that encountered in process operation and scheduling. Because of the presence bilinear terms, traditional formulation nonconvex. Consequently, there a need to develop computationally efficient easy-to-implement global-optimization techniques. In this paper, new approach proposed based on three concepts: linearization by discretizing nonlinear variables, preprocessing using implicit enumeration discretization form convex-hull which limits size...
Propionic acid, n-propanol and propylene are chemicals in a variety of markets ranging from plastics to food preservatives. Propylene is an important commodity monomer precursor many chemical products, while propionic acid smaller volume with growth potential. In place petrochemicals, carbohydrates possible feedstock all three by fermentative production followed synthetic derivation through reductions. There few studies that directly assess the industrial practicality this process despite...
This paper proposes a new general systematic approach for the design of optimal pathways biorefinery. The includes set sequential steps superstructure generation and disjunctive programming models pathway optimization. allows identification biorefinery configurations given criterion (for example economic, environmental, or safety, etc). proposed user to solve easily (through subproblems) difficult problem, it can be applied any case study; in this paper, is study optimization bioalcohols...
This article presents a new global optimization method for the interplant water integration based on properties to characterize streams with numerous components. The problem is formulated as an mixed‐integer non‐linear programming (MINLP) model superstructure that involves all possible options of interest (i.e., reuse and recycle in same other plants set shared treatment units). formulation exhibits multiple local minima, overcome this problem, proposes effective branching rules addition two...
Smoking cigarettes in the enclosed environment of a car leads to contamination car's microenvironment with residual tobacco smoke pollution (TSP). Surface wipe, air, and dust samples were collected used cars sold by nonsmokers (n = 40) smokers 87) analyzed for nicotine. Primary drivers interviewed about smoking behavior restrictions, interiors inspected investigate (a) differences dustiness, signs past smoking, ventilation use, mileage, passenger cabin volume among without in-car bans (b)...
Recovery of carboxylic acids from fermentation broths is an active area research due to ongoing interest in utilizing renewable feedstock for chemical production. Several recent studies have focused on recovery via liquid–liquid extraction using reactive solvents such as high molecular weight amines because they yield significantly higher partition ratios. However, these tend be more expensive than conventional physical solvents. We measured the phase equilibrium behavior extracting...
In human liver, unconjugated bile acids can be formed by the action of acid-CoA thioesterases (BACTEs), whereas acid conjugation with taurine or glycine (amidation) is catalyzed acid-CoA:amino N-acyltransferases (BACATs). Both pathways exist in peroxisomes and cytosol. Bile amidation facilitates biliary excretion, accumulation may become hepatotoxic. We hypothesized that formation conjugated from their common substrate thioesters BACTE BACAT regulated via peroxisome proliferator-activated...
We present a detailed analysis of weathering fluxes at Lake Baikal, the largest lake in world, using major element, trace element and isotope geochemistry inflowing rivers, itself, its sediments. Our objective is to assess how records could be used understand river-catchment-scale denudation processes. Total rates as obtained from meteoric 10Be/9Be, are an order magnitude lower than global average, 16–35 t km−2 yr−1. Chemical riverine dissolved load discharge are, on other hand, same range...
Abstract Objectives Due to the high demand for all-ceramic restorations, monolithic zirconia restorations are nowadays frequently used. With adult orthodontic treatments, orthodontists need be mindful of quality their brackets bonding this type material, as it requires special conditioning. This study aimed compare different surface treatments when metal or ceramic brackets. The objectives shear bond strength; amount adhesive remaining on material; incidence adhesive, cohesive, and mixed...
Abstract Background Hospitalized patients with COVID-19 experience high mortality rates, ranging from 10% to 30%. Combined casirivimab and imdevimab (CAS+IMD) is authorized for use in outpatients post-exposure prophylaxis. The UK-based platform RECOVERY study reported improved survival hospitalized seronegative treated CAS+IMD; however, most of the world, anti-spike monoclonal antibody therapy currently not approved patients. Methods In this phase I/II/III double-blind placebo-controlled...
Automated generate-and-validate (G&V) program repair techniques typically rely on hard-coded rules, only fix bugs following specific patterns, and are hard to adapt different programming languages. We propose ENCORE, a new G&V technique, which uses ensemble learning convolutional neural machine translation (NMT) models automatically in multiple take advantage of the randomness hyper-parameter tuning build that combine them using learning. This NMT approach outperforms standard long...
HIV-infected children suffer from higher levels of treatment failure compared to adults. Immunoactivation, including humoral immunoactivation reflected by increased immunoglobulin levels, is believed occur early during HIV infection. Therefore, we wanted investigate alteration in association with response children.A nested case-control study was conducted using clinical data collected 68 enrolled at the National Hospital Pediatrics, Vietnam.The results showed that CD4 T-cell counts,...