- Acute Lymphoblastic Leukemia research
- Intracerebral and Subarachnoid Hemorrhage Research
- Global Maternal and Child Health
- Chronic Myeloid Leukemia Treatments
- Fetal and Pediatric Neurological Disorders
- Childhood Cancer Survivors' Quality of Life
- Burn Injury Management and Outcomes
- Chronic Lymphocytic Leukemia Research
- Climate Change and Health Impacts
- Innovations in Medical Education
- Injury Epidemiology and Prevention
- Reproductive Health and Contraception
- Cerebrospinal fluid and hydrocephalus
- Acute Ischemic Stroke Management
- Maternal and Perinatal Health Interventions
- Diversity and Career in Medicine
- MRI in cancer diagnosis
- Hospital Admissions and Outcomes
Albert Einstein College of Medicine
2024
Children's Hospital at Montefiore
2024
Johns Hopkins University
2016-2020
Johns Hopkins Medicine
2016-2020
CMH Lahore Medical College and Institute of Dentistry
2016
California Institute of Behavioral Neurosciences and Psychology (United States)
2016
Social support and ego resiliency play a great role in maintaining the physical mental health of patients with burn injuries. The present study has been designed to compare levels degree social injury their healthy counterparts.This was conducted two teaching hospitals Lahore, Pakistan from May 2015 July 2015. A total 80 presenting outpatient departments general surgery, plastic centers these were surveyed conveniently, for comparison, minor ailments, routine checkups or follow-ups...
Inadequate myelosuppression during maintenance therapy for acute lymphoblastic leukemia (ALL) is associated with an increased risk of relapse. One mechanism skewed metabolism 6-mercaptopurine (6MP), a major component therapy, which results in preferential formation the hepatotoxic metabolite (6-methyl mercaptopurine [6MMP]) low levels antileukemic metabolite, 6-thioguanine nucleotides (6TGN). Allopurinol can modify 6MP to favor 6TGN production and reduce 6MMP.Patients were considered...
Previous research indicates that attitudes to pregnancy and motherhood are influenced by social values, culture religion. This study explores the relationship between support unwanted among Pakistani women. cross-sectional was conducted at four teaching hospitals in Lahore 2014. A total of 500 pregnant women who visited hospitals' obstetrics gynecology departments were asked respond a questionnaire consisting respondents' characteristics Social Provisions Scale (SPS). Logistic regression...
OBJECTIVES/SPECIFIC AIMS: This study aims to assess the safety, feasibility, clinical benefits and pharmacodynamics of adding allopurinol standard maintenance therapy that includes 6-mecaptopurine (6-MP) in pediatric patients with acute lymphoblastic leukemia (ALL) or lymphoma. Our goal is investigate if improves hepatotoxicity GI toxicity, it safely decreases neutrophil count (ANC), reduces 6-MP dose required during chemotherapy, works through our hypothesized mechanism by lowering levels...
Background: Acute obstructive hydrocephalus secondary to spontaneous intracerebral/intraventricular hemorrhage (ICH/IVH) requires early cerebrospinal fluid (CSF) drainage reduce intracranial pressure (ICP). Extensive CSF may IVH clot burden. We characterize dynamics, strategies and impact on end of treatment (EOT) volume (72 hours post randomization [Rand]) in the CLEAR III trial. Methods: Prospective analysis output all 500 patients enrolled trial, a multicenter, double-blind, randomized...
Background: Early blood–brain barrier damage after acute intracerebral hemorrhage (ICH) has been qualitatively linked to subsequent perihematoma edema (PHE) formation. In this quantitative study, it was investigated whether the degree of evident on MRI scans related ICH and PHE volume in patients with ICH. Methods: Analysis performed a database who underwent perfusion-weighted imaging (PWI) gadolinium within 7 days onset. Postprocessing PWI source images estimate changes permeability...