A5108941835- HIV, TB, and STIs Epidemiology
- Reproductive tract infections research
- Immune cells in cancer
- Mesenchymal stem cell research
- Syphilis Diagnosis and Treatment
- Hydrogen's biological and therapeutic effects
- Ethics in Clinical Research
- American Political and Social Dynamics
- Medical Imaging and Analysis
- Poetry Analysis and Criticism
- Italian Fascism and Post-war Society
- Plant Stress Responses and Tolerance
- HIV, Drug Use, Sexual Risk
- Smart Materials for Construction
- BRCA gene mutations in cancer
- Osteomyelitis and Bone Disorders Research
- Industrial Vision Systems and Defect Detection
- Orthopedic Infections and Treatments
- Extracellular vesicles in disease
- Computational and Text Analysis Methods
- Optical measurement and interference techniques
- Air Quality and Health Impacts
- Infrastructure Maintenance and Monitoring
- Historical Geopolitical and Social Dynamics
- Neurogenesis and neuroplasticity mechanisms
Xinjiang Agricultural University
2023
Dalian Jiaotong University
2023
Zhengzhou University
2015-2022
Henan Provincial People's Hospital
2022
Xi'an Jiaotong University
1997-2021
Melbourne Sexual Health Centre
2021
Monash University
2021
The University of Melbourne
2021
Alfred Health
2021
National Health and Family Planning Commission
2019
Mesenchymal stem cells (MSCs) have been employed successfully to treat various immune disorders in animal models and clinical settings. Our previous studies shown that MSCs can become highly immunosuppressive upon stimulation by inflammatory cytokines, an effect exerted through the concerted action of chemokines nitric oxide (NO). Here, we show also enhance responses. This immune-promoting occurred when proinflammatory cytokines were inadequate elicit sufficient NO production. When inducible...
Mammalian mesenchymal stem cells (MSCs) have been shown to be strongly immunosuppressive in both animal disease models and human clinical trials. We reported that the key molecule mediating immunosuppression by MSCs is species dependent: indoleamine 2,3-dioxygenase (IDO) inducible nitric oxide synthase (iNOS) mouse. In present study, we isolated from several mammalian species, each of a different genus, investigated involvement IDO iNOS during MSC-mediated immunosuppression. The...
The global optimization of sensor locations for structural health monitoring systems is studied in this paper. First, the performance function based on damage detection presented. Then, genetic algorithms (GAs) are adopted to search optimal sensors. However, simple GAs can result infeasible solutions problem. Some improved strategies presented paper, such as crossover identification code, mutation two gene bits, and convergence. analytical results from algorithm compared with penalty method...
The PLATZ (plant AT protein and zinc-binding protein) transcription factor family is involved in the regulation of plant growth development stress response. In this study, 24 SlPLATZs were identified from cultivated tomato genome classified into four groups based on similarity conserved patterns among members same subfamily. Fragment duplication was an important way to expand SlPLATZ gene tomatoes, sequential order genes evolution monocotyledonous dicotyledonous plants roles they played...
A nanostructured surface layer with thickness of about 20 µm was formed on commercially pure zirconium using mechanical attrition treatment (SMAT). The microstructural features the were systematically investigated optical microscopy (OM), x-ray diffraction (XRD), transmission electron (TEM) and high-resolution (HRTEM), respectively. Based results obtained, a grain refinement mechanism induced by plastic deformation during SMAT Zr is proposed. At initial stage SMAT, twinning dominates divides...
Background & aims: Biopsy is the gold standard for staging liver fibrosis, but it may be accompanied by complications. As an alternative, non-invasive markers such as transient elastography (for fibrosis) and certain combinations of routine blood (liver function tests, full count) have been developed although their clinical significance remains controversial. Here, we compare diagnostic values fibrosis in patients with chronic hepatitis B infection.Methods: Transient laboratory tests were...
Objective: To investigate the clinicopathological characteristics and prognosis of mature T/NK cell lymphomas with aberrant CD20 or CD79α expression. Methods: A retrospective analysis 641 cases lymphoma diagnosed from January 2014 to December 2020 was performed, 14 CD20-positive one case CD79α-positive T/NK-cell were identified. Histological examination, immunohistochemical characterization, in situ hybridization for Epstein-Barr virus encoded early RNA (EBER), PCR testing immunoglobulin T...
<h3>Background</h3> While syphilis transmission is increasing, precisely how Treponema pallidum transmitted sexually unclear. This study of MSM with early determined the frequency shedding from potentially asymptomatic sites and stage most frequent shedding. <h3>Methods</h3> were recruited between 2015 2019, at Melbourne Sexual Health Centre, Australia. Men eligible if they reported sex men during previous year, aged ≥18 years had laboratory-confirmed primary, secondary, or latent syphilis....
<h3>Background</h3> Serology is negative in a proportion of primary syphilis cases where Treponema pallidum polymerase chain reaction (PCR) testing positive. We aimed to identify discordant, T. PCR-positive, serology and any clinical or laboratory factors associated with failure subsequently seroconvert. <h3>Methods</h3> Serodiscordant that were PCR positive (including rapid plasma reagin, particle agglutination, enzyme immunoassay chemiluminescence assay) identified from the Melbourne...
Objective: Osteomyelitis (OM) is an acute or chronic inflammatory process, characterized by severe inflammation and progressive bone destruction. Limited efforts have been made to explore the genetic basis of OM.Method: The genome-wide association study data set OM was obtained from UK Biobank. A transcriptome-wide (TWAS) conducted FUSION tool using gene expression reference weights lymphocytes blood. OM-associated genes identified TWAS were subjected ontology (GO) enrichment analysis...
To investigate the roles of angiotensin-converting enzyme 2 (ACE2) in ozone-induced pulmonary inflammation and airway remodeling mice.Sixteen wild-type (WT) C57BL/6J mice 16 ACE2 knock-out (KO) were exposed to either filtered air or ozone (0.8 ppm) for 3 h per day 5 consecutive days. Masson's staining HE used observe lung pathologies. Bronchoalveolar lavage fluid (BALF) was collected total cell count determined. The proteins cytokines BALF determined by BCA ELISA method. transcription levels...
<h3>Background</h3> Neisseria gonorrhoeae can be cultured from saliva in men with pharyngeal gonorrhoea and could theoretically transmitted the pharynx to urethra when is used as a lubricant for masturbation. To explore this issue, we developed mathematical models transmission of at each oropharynx, anorectum among who have sex (MSM). <h3>Methods</h3> Model 1 included routes (oral sex, anal rimming, kissing, three sequential practices) previously validated. In 2, added masturbation model 1....
<h3>Background</h3> We aimed to develop machine learning models and evaluate their performance in predicting HIV sexually transmitted infections (STIs) diagnosis based on a cohort of Australian men who have sex with (MSM). <h3>Methods</h3> collected clinical records 21,273 MSM during 2011–2017. compared accuracies for STIs (syphilis, gonorrhoea, chlamydia) using four approaches against multivariable logistic regression (MLR) model. <h3>Results</h3> Machine consistently outperformed MLR....