A5058884229- Skin Protection and Aging
- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- melanin and skin pigmentation
- Genetic and rare skin diseases.
- Autoimmune and Inflammatory Disorders Research
- Laser Applications in Dentistry and Medicine
- Proteoglycans and glycosaminoglycans research
- Ocular Surface and Contact Lens
- Insect Utilization and Effects
- Research on Leishmaniasis Studies
- Nonmelanoma Skin Cancer Studies
- Nail Diseases and Treatments
- Olfactory and Sensory Function Studies
- Mycobacterium research and diagnosis
- Skin and Cellular Biology Research
- Ovarian cancer diagnosis and treatment
- Cancer Risks and Factors
- Diabetes Management and Research
- Hair Growth and Disorders
- Genomics, phytochemicals, and oxidative stress
- Medical and Biological Ozone Research
- Metastasis and carcinoma case studies
- Infectious Diseases and Mycology
- Dermatological and Skeletal Disorders
Policlinico San Matteo Fondazione
2010-2012
Istituti di Ricovero e Cura a Carattere Scientifico
2010-2012
University of Pavia
2010-2012
Strategies for successful aging, including the use of food supplements, are part approach to support skin youthfulness. To demonstrate efficacy fermented bilberry extract (FBE) against aging and uneven complexion, a clinical trial was carried out on 66 subjects with visible "crow's feet" wrinkles, mild-to-moderate slackness, tone. The wrinkle depth, smoothness (Ra) roughness (Rz), firmness (R0) elasticity (R2), coloration (ITA°), antioxidant capacity were measured before after 28 (D28), 56...
Belight3TM, a nutricosmetic formulation containing polyphenol-rich extracts, has previously been demonstrated to be safe and effective in brightening skin color dark spots clinical study involving Asian volunteers. The aim of this was investigate the efficacy lightening Caucasian population, which is characterized by lighter pigmentation greater visibility hyperpigmentation, as well determine whether supplementation increased sensitivity UV exposure. A randomized, double-blind,...
Hyaluronic acid (HA) content in the skin progressively decreases with age, thus its supplementation - either topical, oral and by subcutaneous injection represents a first line intervention to ameliorate aging signs. The present multicenter randomized placebo-controlled trial (RCT) evaluated antiaging efficacy of an In&Out treatment, i.e. concomitant through cosmetic cream, administration specifically designed HAs, Full Spectrum HAs (FS-HA), multiethnic population instrumental...
Hyaluronic acid (HA) content in the skin progressively decreases with age; thus, its supplementation—either topical, oral, and by subcutaneous injection—represents a first-line intervention to ameliorate aging signs. The present multicenter randomized placebo-controlled trial (RCT) evaluated antiaging efficacy of an In&Out treatment, i.e., concomitant through cosmetic cream, oral administration specifically designed HAs, full-spectrum HAs (FS-HAs), multiethnic population using...
Hyaluronic acid (HA) has long been used for its anti-age properties, as an ingredient in both topical applications and food supplements. In this study, a novel sodium hyaluronate, based on the innovative full spectrum technology, was administered of cosmetic product main constituent supplement to evaluate efficacy counteracting skin ageing signs. Seventy-five female subjects were randomly assigned following treatments 4 weeks: active placebo product, supplement, combination two products...
This study aimed at investigating the effect of a food supplement in ameliorating skin, hair, and nails conditions. An open-label on 21 women with mild-to-moderate aging all over face (including wrinkles/fine lines, loss skin firmness/elasticity, normal to dry skin), acute telogen effluvium, brittle/fragile was conducted. Skin (moisturization, elasticity, profilometry, thickness), hair (pull test phototricogram), (clinical analysis nail plate status) parameters were measured baseline, after...
The skin is a barrier organ subjected to lifelong exposure internal and external factors influencing both its biological response appearance. A randomized split-face study was carried out on 22 adult female outdoor workers using an artichoke leaf extract (CynageTM). product’s efficacy measured before after 28 days of use. following parameters were measured: wrinkle depth, roughness, radiance, assess the effect appearance; Ferric Reducing Antioxidant Power (FRAP), total antioxidant capacity;...
L’efficacia della Ciclosporina-A (CsA) nel trattamento psoriasi e nota da 30 anni. La sua maggiore limitazione pero correlata al rischio di eventi avversi quali l’ipertensione arteriosa l’alterazione funzionalita renale che sembrerebbero non solo dose-dipendenti ma anche proporzionali alla durata terapia. Pertanto, la possibilita formulare uno schema in grado controllare efficacemente le manifestazioni cliniche lungo termine con un profilo sicurezza accettabile risulta sempre piu importante...
Abstract Aging generates an undesirable skin appearance, including laxity and a crepe-like appearance. Profhilo® Figura body cream is multi-active remodelling firming comprising low- high-molecular-weight hyaluronic acids Matrixyl® 3000. The objective of this study was to investigate the effectiveness moisturize improve elasticity firmness. Women aged 30-65 years, with tendency for dry mild-to-moderate atony (characterized by loss) applied daily 28 days on their leg area. Skin...
Belight3TM, a nutricosmetic formulation containing polyphenol-rich extracts has previously been demonstrated to be safe and effective in brightening skin color dark spots clinical study involving Asian volunteers. The aim of this was investigate the efficacy lightening Caucasian population, which is characterized by lighter pigmentation greater visibility hyperpigmentation, as well determine whether supplementation increased sensitivity UV exposure. A randomized, double-blind,...
Efalizumab e un anticorpo monoclonale umanizzato ad attivita anti-CD11a, il cui meccanismo d’azione risiede nel blocco dell’attivazione, adesione migrazione delle cellule T, approvato per trattamento della psoriasi in placche di grado moderato-severo ritirato dal commercio l’insorgenza letali complicanze natura infettivologica. Presentiamo tre casi pazienti affetti da grave trattati con Efalizumab, ottimo controllo del quadro clinico dopo alcuni mesi trattamento. Il ritiro farmaco ha...
La micobatteriosi atipica da Mycobacterium Marinum e una rara infezione dovuta a contatto di cute non integra con acque contaminate o animali acquatici infetti. Clinicamente si manifesta la comparsa noduli infiltrati in sede lesione, ma occasionalmente puo presentarsi andamento lineare simil-sporotricoide. Per corretta diagnosi sono fondamentali un’anamnesi accurata, un attento esame obiettivo, nonche istologico colturale. terapia antibiotica mirata permette risoluzione completa delle...
Descriviamo il caso di una donna 42 anni affetta da psoriasi volgare in remissione clinica completa 15 settimane, che ha presentato l’insorgenza un’eruzione pustolosa diffusa su gran parte della superficie cuta-nea, con febbre e condizioni generali scadenti dopo l’assunzione Ciprofloxacina per trattamento un’infezione delle vie urinarie. In base al quadro clinico ed all’anamnesi pregressa eruzione cutanea stata posta diagnosi generalizzata indotta Ciprofloxacina. Dopo sistemico...
Porokeratosis is a group of rare disorders epidermal keratinization with inherited and acquired forms. Clini-cally, porokeratosis characterized by annular lesions hyperkeratotic “collarette” or, more rarely, linear plaques. The occurrence in patients iaterogenic immunosuppression has already been described literature, particularly solid organ transplant recipients. developing under immunosuppressive treatment after allogeneic bone marrow transplantation less common. We describe 16-year old...
The objective of the study was to assess frequency nail involvement in psoriasis patients and detect relationship between different clinical parameters. 178 with were in-cluded (54 women 124 men) for each patient calculated PASI NAPSI value, interview conducted order anamnestic features. 76.9% subjects showed signs (NAPSI ≥1). Nail lesions associated longer duration (15.6 vs 14.0 years). average score significantly higher individuals (12.0 8.7 p=0.06). 85.7% psoriatic arthritis involvement....
Acral Peeling Skin Syndrome is a rare autosomal recessive disorder characterized by painless blistering within the stratum corneum or at junction of and granulosum. As name implies, acral variant predominantly affects hands feet, although generalized has been described. Here we report case young man with similar symptoms.
La psoriasi e una patologia cutanea infiammatoria cronica con prevalenza tra lo 0.8 l’11%. L’epatite C infettiva del 2.6% a livello mondiale. Di recente interesse la valutazione di possi-bile correlazione non casuale le due patologie in relazione all’utilizzo nella terapia della farmaci immunosoppressori (anti-TNFα, ciclosporina) grado causare riattivazione infezioni cui HCV. Lo scopo questo studio dell’epatite popolazione pazienti psoria-sici, presenza dell’infezione gravita difficolta...
BACKGROUND: Skin dryness is an effect of ageing and environmental stress, leading to alterations the barrier properties skin. The aim this study was evaluate hydration/moisturizing effects a hyaluronic acid-based cream (Viscoderm Hydrobooster® Cream, IBSA Farmaceutici Italia; Lodi, Italy) applied forearm or face skin.METHODS: Twenty healthy volunteers with evidence skin were enrolled asked apply Viscoderm® Hydrobooster (IBSA Italia). hydration determined by noninvasive instrumental analysis...