A5095096214- 3D Printing in Biomedical Research
- Electrochemical Analysis and Applications
- Neuroscience and Neural Engineering
Cardiff University
2024
The development of the mouse neocortex in vitro mimics vivo development. Mouse brain cultures can serve as a model system for cortical first 2 wk and adult cortex from to 4 vitro. organotypic slice develop high-frequency network oscillations at γ frequency after exhibit increased heterogeneity variability culture.
Abstract Murine organotypic brain slice cultures have been widely used in neuroscientific research and are offering the opportunity to study neuronal function under normal disease conditions. Despite brought application, mechanisms governing maturation of immature cortical circuits vitro not well understood. In this study, we present a detailed investigation into development neocortex . Utilizing holistic approach, studied whole-hemisphere from postnatal mice tracked somatosensory area over...