A5092113452- Computational Drug Discovery Methods
- Drug-Induced Hepatotoxicity and Protection
- Pharmacogenetics and Drug Metabolism
- Receptor Mechanisms and Signaling
- Metabolomics and Mass Spectrometry Studies
- Chemokine receptors and signaling
- Pharmacological Effects of Medicinal Plants
- Machine Learning in Materials Science
- Protein Structure and Dynamics
- Cytokine Signaling Pathways and Interactions
Bombay College of Pharmacy
2023-2025
Drug-induced liver injury (DILI) has been a significant challenge in drug discovery, often leading to clinical trial failures and necessitating withdrawals. Over the last decade, existing suite of
Drug-induced liver injury (DILI) has been significant challenge in drug discovery, often leading to clinical trial failures and necessitating withdrawals. The existing suite of vitro proxy-DILI assays is generally effective at identifying compounds with hepatotoxicity. However, there considerable interest enhancing silico prediction DILI because it allows for the evaluation large sets more quickly cost-effectively, particularly early stages projects. In this study, we aim study ML models...