- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Peroxisome Proliferator-Activated Receptors
- Cardiac and Coronary Surgery Techniques
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cardiac Arrest and Resuscitation
- Hemoglobin structure and function
- Liver Disease and Transplantation
- Congenital Anomalies and Fetal Surgery
- Liver Disease Diagnosis and Treatment
- Platelet Disorders and Treatments
- Education during COVID-19 pandemic
- Hemophilia Treatment and Research
- Electrospun Nanofibers in Biomedical Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Neurological Disorders and Treatments
- Congenital Heart Disease Studies
- Occupational Health and Burnout
- Lymphatic System and Diseases
- Congenital heart defects research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiac, Anesthesia and Surgical Outcomes
- Body Contouring and Surgery
- Tissue Engineering and Regenerative Medicine
- Healthcare Regulation
- Parasites and Host Interactions
Universidade Federal do Ceará
2025
Centro de Estudos e Sistemas Avançados do Recife
2024
Inserm
2023
Pitié-Salpêtrière Hospital
2023
Sorbonne Université
2023
Universidade Federal de Pernambuco
2016-2017
Fundação Oswaldo Cruz
1954-2017
Hospital de Faro EPE
2010
K. alvarezii is a red macroalgae cultivated on large scale in Asian countries. In Brazil, it states such as Piaui, Rio de Janeiro, and São Paulo due to the high economic value for food industry given concentrations of carrageenan, hydrocolloid formed mainly by carbohydrates, used gelling agent emulsifier. Therefore, aggregate its protein content, goal was identify proteins from biotechnological potentials against human pathogens. The extract produced Na+-acetate buffer most efficient...
Non-alcoholic fatty liver disease (NAFLD) defines a wide spectrum of diseases that extends from simple steatosis to non-alcoholic steatohepatitis. Although the pathogenesis NAFLD remains undefined, it is recognized insulin resistance present in almost all patients who develop this disease. Thiazolidinediones (TZDs) act as an sensitizer and have been used treatment with type 2 diabetes other insulin-resistant conditions, including NAFLD. Hence, therapy insulin-sensitizing drugs should ideally...
A method of studying hemostasis in vivo, employing the well-known dog's hind limb preparation, used by physiologists for study vasomotor properties circulatory system this region, is presented here detail. Using noncoagulable blood and controlling flow through normal 8.5 minutes on average obtained, if certain conditions are observed. The importance innervation maintenance confirmed, since cutting femoral nerve or death animal causes to become nonhemostatic. Under preparation may function 6...
SummaryEmploying the dog's hind-leg which permits a controlled study of bleeding time, it has been determined that refrigeration blood for 10 minutes at 1-2°C causes to lose its normal hemostatic properties, not recoverable by heating 37°C. Furthermore violent aeration in air, liberating CO2 and driving pH alkaline side, also renders non-hemostatic, although returning liberated blood, shaking atmospheric air containing 9% CO2, action may be recovered. The mechanism these phenomena, their...
Heart-lung by-pass circulation obtained in dogs by an apparatus improvised the laboratory has shown that from very beginning of outside lung bleeding time increased greatly. The return to normal animal after experiment showed hemostasis returns its figure 30 60 minutes afterwards. This observation agrees with prior observations on different behavior venous and arterial blood as far capacity for is concerned, accordance hemostatic once passed through a heart-lung preparation—all these facts...
22q11.2 deletion syndrome (22q11.2DS) shows significant clinical heterogeneity. This study aimed to explore the association between heterogeneity in 22q11.2DS and parental origin of deletion. The was determined for 61 individuals with by genotyping DNA microsatellite markers single-nucleotide polymorphisms (SNPs). Among individuals, 29 (47.5%) had a maternal deletion, 32 (52.5%) paternal origin. Comparison frequency main features deletions or showed no statistically difference. However,...
Previous studies using dog hind‐leg preparations showed that only arterial blood has hæmostatic activity, the venous rearterialized in vitro being non‐hæmostatic. This loss of activity when reaches and passes capillaries is observed regionally (jugular hepatic veins) mixed (right auricle), which received lymph from thoracic duct. Hæmostatic principles may be lost through capillaries, so was tried as an agent added to blood. Lymph after contact with air, even small concentrations (0·25 ml....
Previous findings employing a physiological method for the study of haemostasis (CRUZ and OLIVEIRA, 1958), showed that only arterial blood is responsible this organic function, venous blood, on contrary, showing marked inhibitory action (CRUZ, OLIVEIRA MAGALHAES, 1958). Such differences in behaviour between appear to indicate interference pulmonary function action. If case, passed repeatedly through lungs without subsequent contact with capillaries different tissues organism, could, being...
Amniotic band syndrome include a spectrum of congenital malformations, varying from constriction rings to major craniofacial and abdominal wall defects due amniotic bands that disrupt fetal parts. The prevalence this condition is 7/10000. Nonetheless malformations such as are even rarer. Pentalogy Cantrell rare complex malformations. In the complete two found: ectopia cordis an defect, however incomplete expressions have been reported. Other or vertebral anomalies may be associated. We...
SUMMARY Obesity is a life-threatening condition characterized by maladaptive remodeling of the visceral white adipose tissue (vWAT), including fibrosis, that drives vWAT metabolic alterations. We previously identified CD9 hi progenitors as main drivers fibrosis in mice and humans. However, how their functions are controlled, especially macrophages, remains largely unknown. found obesity-elicited monocyte-derived macrophages (obeMac) accumulation was considerably elevated prone to...