A5011404804- Gastrointestinal motility and disorders
- Music Therapy and Health
- Pathogenesis and Treatment of Hiccups
- Seedling growth and survival studies
- Mental Health Treatment and Access
- Psychotherapy Techniques and Applications
- Mental Health and Psychiatry
- Plant Disease Management Techniques
- Plant Pathogens and Fungal Diseases
- Soil Carbon and Nitrogen Dynamics
- Plant Physiology and Cultivation Studies
- Complementary and Alternative Medicine Studies
- Composting and Vermicomposting Techniques
University of Southampton
2022-2024
Agricultural Development Advisory Service (United Kingdom)
2023
The Open University
2023
Most patients with irritable bowel syndrome (IBS) are managed in primary care. When first-line therapies for IBS ineffective, the UK National Institute Health and Care Excellence guideline suggests considering low- dose tricyclic antidepressants as second-line treatment, but their effectiveness care is unknown, they infrequently prescribed this setting.
Background Irritable bowel syndrome, characterised by abdominal pain and a change in stool form or frequency, is most often managed primary care. When first-line therapies are ineffective, National Institute for Health Care Excellence guidelines suggest considering low-dose tricyclic antidepressants as second-line treatment, but their effectiveness care unknown they infrequently prescribed general practitioners. Objective To evaluate the clinical cost-effectiveness of titrated amitriptyline...
Background: Irritable bowel syndrome (IBS) can cause troublesome symptoms impacting patients’ quality of life and incur considerable health service resource use. Guidelines suggest low-dose amitriptyline for IBS as second line treatment, but this is rarely prescribed in primary care. Aim: To explore general practitioners’ (GPs) views experiences using IBS. Design Setting: Qualitative interview study with patients GPs England, nested within the ATLANTIS trial versus placebo ( ISRCTN48075063...
Irritable bowel syndrome (IBS) is a common functional disorder that has considerable impact on patient quality of life and substantial societal health care resource costs. Current treatments are often ineffective. Tricyclic antidepressants have shown promise in secondary populations but their effectiveness primary setting remains unclear.ATLANTIS randomised, multi-centre, parallel-group, two-arm, double-blind, placebo-controlled trial low-dose amitriptyline as second-line treatment for IBS...
<h3>Introduction</h3> IBS impacts patients' quality of life and has substantial societal health care resource costs. NICE guidelines recommend considering low-dose amitriptyline if first line treatments are ineffective. However, evidence for patients in primary is unclear few GPs currently prescribe IBS. <h3>Methods</h3> NIHR HTA-funded double-blind, randomised, placebo-controlled, superiority trial (10–30mg participant self-titrated) adults with care. <i>Eligibility:</i> Adults ongoing...
Materials used to replace peat in growing media include wood fibre (WF), often combination with composted bark (BC), coir (CR), green compost (GC), and anaerobic digestate (AD). The physical chemical properties of these materials are relatively well characterised; however, biological less understood. Biological stability is an important factor plant performance. aim this research was identify whether dynamic respirometry methods suitable for measuring assess the effect blending two raw a...
Background Primary care clinicians see people experiencing the full range of mental health problems. Determining when symptoms reflect disorder is complex. The Four-Dimensional Symptom Questionnaire (4DSQ) uniquely distinguishes general distress from depressive and anxiety disorders. It may support diagnostic conversations targeting treatment. Aim To explore peoples’ experiences completing 4DSQ their perceptions resulting score profile across distress, depression, anxiety, physical symptoms....
Abstract The grafting of apple rootstocks on to scions confers benefits including reduced tree size/dwarfing for trellis based growing systems, increased tolerance physiological stress, and pest disease management. current study investigated the effect rootstock selection canker death using eight common M9 337, 337 with Golden Delicious (GD) interstock, EMLA, MM106, M116, M26, Geneva ® G11 G41, in addition six advanced selections from NIAB East Malling breeding programme EMR-001—EMR-006, all...
<h3>Context:</h3> Most patients with irritable bowel syndrome (IBS) are managed in primary care. If first-line therapies ineffective, UK NICE Guidelines suggests considering low dose tricyclic antidepressants (TCAs), but effectiveness care is unknown and TCA infrequently prescribed for IBS this setting. <h3>Objective:</h3> To determine the clinical of amitriptyline (10-30mg) adults <h3>Study Design Analysis:</h3> Randomised, double-blind, placebo-controlled trial. Participants, clinicians,...