Kirsty Scott

ORCID: 0009-0007-7931-1424
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About
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Research Areas
  • Balance, Gait, and Falls Prevention
  • Cerebral Palsy and Movement Disorders
  • Gait Recognition and Analysis
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Diabetic Foot Ulcer Assessment and Management
  • Telemedicine and Telehealth Implementation
  • Palliative Care and End-of-Life Issues
  • Eosinophilic Disorders and Syndromes
  • Viral-associated cancers and disorders
  • Airway Management and Intubation Techniques
  • Lymphoma Diagnosis and Treatment
  • Colorectal Cancer Screening and Detection
  • Non-Invasive Vital Sign Monitoring
  • Muscle activation and electromyography studies
  • Context-Aware Activity Recognition Systems
  • Respiratory Support and Mechanisms
  • Sarcoma Diagnosis and Treatment
  • Mental Health and Patient Involvement
  • Bone Tumor Diagnosis and Treatments
  • Health Systems, Economic Evaluations, Quality of Life
  • Neuroscience of respiration and sleep
  • Diabetes and associated disorders
  • Colorectal Cancer Surgical Treatments
  • Gastrointestinal Tumor Research and Treatment
  • Healthcare Systems and Technology

Insigneo
2020-2025

University of Sheffield
1975-2025

Newcastle University
2025

University of Exeter
2020

Royal Cornwall Hospital Trust
2020

St Austell Community Hospital
2017

Phillips Exeter Academy
2010

St Christopher's Hospice
2009

New Cross Hospital
1988-2002

Wolverhampton Hospital
1980-1994

One hundred and three colorectal carcinoma specimens were examined to determine the value of xylene alcohol fat clearance technique in detecting lymph node metastases. The mesocolon or mesorectum was dissected initially by traditional method all nodes identified histologically. After specimen again further examined. Forty-one obtained from rectum 62 colon. Traditional dissection produced a mean 6.2 per specimen, but following 12.4 found. total number recovered varied two 69 with 18.5...

10.1002/bjs.1800761118 article EN British journal of surgery 1989-11-01

Abstract Background Although digital mobility outcomes (DMOs) can be readily calculated from real-world data collected with wearable devices and ad-hoc algorithms, technical validation is still required. The aim of this paper to comparatively assess validate DMOs estimated using gait six different cohorts, focusing on sequence detection, foot initial contact detection (ICD), cadence (CAD) stride length (SL) estimates. Methods Twenty healthy older adults, 20 people Parkinson’s disease,...

10.1186/s12984-023-01198-5 article EN cc-by Journal of NeuroEngineering and Rehabilitation 2023-06-14
Cameron Kirk Arne Küderle M. Encarna Micó-Amigo Tecla Bonci Anisoara Paraschiv-Ionescu and 95 more Martin Ullrich Abolfazl Soltani Eran Gazit Francesca Salis Lisa Alcock Kamiar Aminian Clemens Becker Stefano Bertuletti Philip M. Brown Ellen Buckley Alma Cantu Anne‐Elie Carsin Marco Caruso Brian Caulfield Andrea Cereatti Lorenzo Chiari Ilaria D’Ascanio Judith García‐Aymerich Clint Hansen Jeffrey M. Hausdorff Hugo Hiden Emily Hume Alison Keogh Felix Kluge Sarah Koch Walter Maetzler Dimitrios Megaritis Arne Mueller Martijn Niessen Luca Palmerini Lars Schwickert Kirsty Scott Basil Sharrack Henrik Sillén David Singleton Beatrix Vereijken Ioannis Vogiatzis Alison J. Yarnall Lynn Rochester Claudia Mazzà Bjoern M. Eskofier Silvia Del Din Francesca Bottin Lorenzo Chiari Cristina Curreli Ilaria D’Ascanio Giorgio Davico Roberta De Michele Giuliano Galimberti Luca Palmerini Saverio Ranciati Luca Reggi Marco Viceconti Lucia D’Apote Jules Desmond Megan Doyle Mary Elliot-Davey Gilles Gnacadja Anja Kassner Beat Knüsel Monika Pocrzepa Nicolas Pourbaix Hoi-Shen Radcliffe Lening Shen Jennifer Simon Jesper Havsol Diana Jarretta Magnus Jörntén‐Karlsson Pierre Mugnier Solange Corriol Rohou Gabriela Luporini Saraiva Henrik Sillén Michael Karl Boettger Igor Knezevic Frank Kramer Paolo Piraino H Trübel Hajar Ahachad Hubert Blain Sylvie Broussous François Canovas Florent Cerret Louis Dagneaux Valérie Driss Florence Galtier Charlote Kaan Stéphanie Miot Eva Murauer Anne-Sophie Vérissimo Daniela Berg Kirsten Emmert Clint Hansen Hanna Hildesheim Jennifer Kudelka Walter Maetzler

Abstract This study aimed to validate a wearable device’s walking speed estimation pipeline, considering complexity, speed, and bout duration. The goal was provide recommendations on the use of devices for real-world mobility analysis. Participants with Parkinson’s Disease, Multiple Sclerosis, Proximal Femoral Fracture, Chronic Obstructive Pulmonary Congestive Heart Failure, healthy older adults (n = 97) were monitored in laboratory (2.5 h), using lower back device. Two pipelines validated...

10.1038/s41598-024-51766-5 article EN cc-by Scientific Reports 2024-01-19

Existing mobility endpoints based on functional performance, physical assessments and patient self-reporting are often affected by lack of sensitivity, limiting their utility in clinical practice. Wearable devices including inertial measurement units (IMUs) can overcome these limitations quantifying digital outcomes (DMOs) both during supervised structured real-world conditions. The validity IMU-based methods the real-world, however, is still limited populations. Rigorous validation...

10.1136/bmjopen-2021-050785 article EN cc-by-nc BMJ Open 2021-12-01

Abstract Physical mobility is essential to health, and patients often rate it as a high-priority clinical outcome. Digital outcomes (DMOs), such real-world gait speed or step count, show promise measures in many medical conditions. However, current research nascent fragmented by discipline. This scoping review maps existing evidence on the utility of DMOs, identifying commonalities across traditional disciplinary divides. In November 2019, 11 databases were searched for records investigating...

10.1038/s41746-021-00513-5 article EN cc-by npj Digital Medicine 2021-10-14

Background This study aimed to explore the acceptability of a wearable device for remotely measuring mobility in Mobilise-D technical validation (TVS), and using digital tools monitor health. Methods Participants ( N = 106) TVS wore waist-worn (McRoberts Dynaport MM + ) one week. Following this, was measured two questionnaires: The Comfort Rating Scale (CRS) previously validated questionnaire. A subset participants n 36) also completed semi-structured interviews further determine their...

10.1177/20552076221150745 article EN cc-by-nc-nd Digital Health 2023-01-01

Introduction: Accurately assessing people’s gait, especially in real-world conditions and case of impaired mobility, is still a challenge due to intrinsic extrinsic factors resulting gait complexity. To improve the estimation gait-related digital mobility outcomes (DMOs) scenarios, this study presents wearable multi-sensor system (INDIP), integrating complementary sensing approaches (two plantar pressure insoles, three inertial units two distance sensors). Methods: The INDIP technical...

10.3389/fbioe.2023.1143248 article EN cc-by Frontiers in Bioengineering and Biotechnology 2023-04-21

Background Wrist-worn inertial sensors are used in digital health for evaluating mobility real-world environments. Preceding the estimation of spatiotemporal gait parameters within long-term recordings, detection is an important step to identify regions interest where occurs, which requires robust algorithms due complexity arm movements. While exist other sensor positions, a comparative validation applied wrist position on data sets across different disease populations missing. Furthermore,...

10.2196/50035 article EN cc-by JMIR Formative Research 2024-05-01

The aim of our study was to determine the five-year survival patients with colorectal carcinoma whose Dukes classification had changed following fat clearance mesocolon or mesorectum.One hundred three were followed up at a special clinic for least five years after surgery. tumors from these previously been given before and clearance.Four status B C as result died malignant disease during follow-up period. After it apparent that survived, on average, 11 months longer than patients. A...

10.1007/bf02047533 article EN Diseases of the Colon & Rectum 1994-02-01

Background Gait characteristics are important risk factors for falls, hospitalisations and mortality in older adults, but the impact of COPD on gait performance remains unclear. We aimed to identify differences between adults with healthy age-matched controls during 1) laboratory tests that included complex movements obstacles, 2) simulated daily-life activities (supervised) 3) free-living (unsupervised). Methods This case–control study used a multi-sensor wearable system (INDIP) obtain...

10.1183/23120541.00159-2023 article EN cc-by-nc ERJ Open Research 2023-08-17

Introduction The clinical assessment of mobility, and walking specifically, is still mainly based on functional tests that lack ecological validity. Thanks to inertial measurement units (IMUs), gait analysis shifting unsupervised monitoring in naturalistic unconstrained settings. However, the extraction clinically relevant parameters from IMU data often depends heuristics-based algorithms rely empirically determined thresholds. These were validated small cohorts supervised Methods Here, a...

10.3389/fneur.2023.1247532 article EN cc-by Frontiers in Neurology 2023-10-16

The L-test is a performance-based measure to assess balance and mobility. Currently, the primary outcome from this test time required finish it. In study we present instrumented (iL-test), an wherein mobility evaluated by means of wearable inertial sensor worn at lower back. We analyzed data 113 people across seven cohorts: healthy adults, chronic obstructive pulmonary disease, multiple sclerosis, congestive heart failure, Parkinson's proximal femoral fracture, transfemoral amputation....

10.1109/tnsre.2025.3531723 article EN cc-by IEEE Transactions on Neural Systems and Rehabilitation Engineering 2025-01-01

Background Recent technological advances in wearable devices offer new potential for measuring mobility real-world contexts. Mobilise-D has validated digital outcomes to provide novel and end points clinical research of 4 different long-term health conditions (Parkinson disease, multiple sclerosis, chronic obstructive pulmonary proximal femoral fracture). These also unique information that is important patients; however, there limited literature explores the optimal methods achieve this,...

10.2196/68782 article EN cc-by JMIR Formative Research 2025-03-11

No AccessJournal of Urology1 Dec 1980A Case Polyorchidism with Testicular Teratoma K.W.M. Scott ScottK.W.M. More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)55739-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail A patient duplication the testis who presented initially torsion a right inguinal is described. Subsequently, malignant teratoma trophoblastic type (choriocarcinoma)...

10.1016/s0022-5347(17)55739-0 article EN The Journal of Urology 1980-12-01

The cross-sectional area of diaphragmatic muscle fibres was measured using a Quantimet 720 image analysis system in 18 patients with emphysema and six control non-emphysematous patients. technique proved to be an accurate method measuring fibre much more rapid than the previously described methods. mean emphysematous group 1069-5 mum2 this significantly greater which 851-0 mum2. In nine who died from chronic airways obstruction had larger non-fatal respiratory disease. showed marked increase...

10.1002/path.1711200208 article EN The Journal of Pathology 1976-10-01

Continuous monitoring by wearable technology is ideal for quantifying mobility outcomes in “real-world” conditions. Concurrent factors such as validity, usability, and acceptability of need to be accounted when choosing a device. This study proposes bespoke methodology focused on defining decision matrix allow effective making. A weighting system based responses (n = 69) from purpose-built questionnaire circulated within the IMI Mobilise-D consortium its external collaborators was...

10.3390/s20226509 article EN cc-by Sensors 2020-11-14

Gait analysis is commonly performed in standardized environments, but there a growing interest assessing gait also ecological conditions. In this regard, an important limitation the lack of accurate mobile gold standard for validating any wearable system, such as continuous monitoring devices mounted on trunk or wrist. This study therefore deals with development and validation new multi-sensor-based system digital assessment free-living particular, results obtained from five healthy subjects...

10.1109/embc46164.2021.9630392 article EN 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) 2021-11-01

There is growing interest in the quantification of gait as part complex motor tasks. This requires events (GEs) to be detected under conditions different from straight walking. study aimed propose and validate a new marker-based GE detection method, which also suitable for curvilinear walking step negotiation. The method was first tested against existing algorithms using data healthy young adults (YA, n = 20) then assessed 10 individuals following five cohorts: older adults, chronic...

10.3389/fbioe.2022.868928 article EN cc-by Frontiers in Bioengineering and Biotechnology 2022-06-02

Measuring mobility in daily life entails dealing with confounding factors arising from multiple sources, including pathological characteristics, patient specific walking strategies, environment/context, and purpose of the task. The primary aim this study is to propose validate a protocol for simulating real-world gait accounting all these within single set observations, while ensuring minimisation participant burden safety.The included eight motor tasks at varying speed, incline/steps,...

10.1186/s12984-022-01116-1 article EN cc-by Journal of NeuroEngineering and Rehabilitation 2022-12-15

Glycated haemoglobin and glycated protein (fructosamine) blood glucose concentrations were measured in samples collected from 75 patients at necropsy. Estimation of was a poor indicator glycaemia before death. Measurement by affinity chromatography distinguished non-diabetic diabetic patients. The distinction not as clear cut when HbA1 estimated using electroendosmosis. Seven patients, who necropsy had no known history diabetes, the range. Two these found to be diabetic, diabetes been...

10.1136/jcp.41.4.415 article EN Journal of Clinical Pathology 1988-04-01

Hypertrophy of the bronchial mucous glands was measured by Reid index method in 359 specimens right main bronchus obtained from consecutive autopsies performed a general hospital Glasgow. 119 these cases, were also point-counting technique. There close correlation between 2 methods estimating gland size, and retains useful place both as quick measurement for routine use epidemiologic studies. total incidence hypertrophy range observed bronchitis, which defined greater than 0.50 or point...

10.1164/arrd.1973.107.2.239 article EN PubMed 1973-02-01

Abstract Background: Although digital mobility outcomes (DMOs) can be readily calculated from real-world data collected with wearable devices (WD) and ad-hoc algorithms, technical validation is still required. The aim of this paper to comparatively assess validate DMOs estimated using gait six different cohorts, focusing on sequence detection (GSD), foot initial contact (ICD), cadence (CAD) stride length (SL) estimates. Methods: Twenty healthy older adults, 20 people Parkinson’s disease,...

10.21203/rs.3.rs-2088115/v1 preprint EN cc-by Research Square (Research Square) 2022-09-28
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