A5075042287- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cerebral Palsy and Movement Disorders
- Long-Term Effects of COVID-19
- Balance, Gait, and Falls Prevention
- COVID-19 and Mental Health
- Sleep and related disorders
- Intensive Care Unit Cognitive Disorders
- Effects of Vibration on Health
- Stroke Rehabilitation and Recovery
- Parkinson's Disease Mechanisms and Treatments
- Frailty in Older Adults
- Asthma and respiratory diseases
- Tryptophan and brain disorders
- Health, psychology, and well-being
- Diabetic Foot Ulcer Assessment and Management
- Telemedicine and Telehealth Implementation
- Medical Imaging and Analysis
- Nutrition and Health in Aging
- Mobile Health and mHealth Applications
- Advanced Computing and Algorithms
- Cardiovascular and exercise physiology
- Technology Use by Older Adults
- Geriatric Care and Nursing Homes
- Multiple Sclerosis Research Studies
- Heart Rate Variability and Autonomic Control
University Hospital Schleswig-Holstein
2022-2025
Kiel University
2020-2025
University of Lübeck
2022-2025
Universitäts Hautklinik Kiel
2024
University Medical Center
2022
University Hospital and Clinics
2022
Abstract This study aimed to validate a wearable device’s walking speed estimation pipeline, considering complexity, speed, and bout duration. The goal was provide recommendations on the use of devices for real-world mobility analysis. Participants with Parkinson’s Disease, Multiple Sclerosis, Proximal Femoral Fracture, Chronic Obstructive Pulmonary Congestive Heart Failure, healthy older adults (n = 97) were monitored in laboratory (2.5 h), using lower back device. Two pipelines validated...
The Comprehensive Geriatric Assessment (CGA) records geriatric syndromes in a standardized manner, allowing individualized treatment tailored to the patient's needs and resources. Its use has shown beneficial effect on functional outcome survival of patients. A recently published German S1 guideline for level 2 CGA provides recommendations broad variety different assessment instruments each syndrome. However, actual routine clinical practice its consistency with current state literature not...
Motor and cognitive deficits consequently mobility problems are common in geriatric patients. The currently available methods for diagnosis the evaluation of treatment this vulnerable cohort limited. aims ComOn (COgnitive interactions Older populatioN) study (i) to define quantitative markers with clinical relevance motor deficits, (ii) investigate interaction between both (iii) assess health status as well outcome 1000 inpatients hospitals Kiel (Germany), Brescia (Italy), Porto (Portugal),...
Abstract Long-term changes in health-related quality of life (HrQoL) after SARS-CoV-2 infection are common, but their causes and consequences poorly understood. This prospective, population-based study examined associations between HrQoL 49 demographic clinical variables. was assessed using the European Quality-of-Life-5-Dimensions-5-Level-Version 3,475 participants (56% female; aged 18–88 years) approximately 9 months (baseline) 26 (follow-up) initial infection. Results were compared with...
Abstract Background Fatigue is a prevalent and debilitating symptom in many chronic conditions, including immune-mediated inflammatory diseases (IMIDs) neurodegenerative (NDDs). often fluctuates significantly within between days, yet traditional patient-reported outcomes (PROs) typically rely on recall periods of week or more, potentially missing these short-term variations. The development digital tools, such as electronic diaries (eDiaries), offers unique opportunity to collect granular,...
Problems with fatigue and sleep are highly prevalent in patients chronic diseases often rated among the most disabling symptoms, impairing their activities of daily living health-related quality life (HRQoL). Currently, they evaluated primarily via Patient Reported Outcomes (PROs), which can suffer from recall biases have limited sensitivity to temporal variations. Objective measurements wearable sensors allow reliably quantify disease state, changes HRQoL, evaluate therapeutic outcomes....
Current assessments of fatigue and sleepiness rely on patient reported outcomes (PROs), which are subjective prone to recall bias. The current study investigated the use gait variability in "real world" identify daytime sleepiness. Inertial measurement units were worn lower backs 159 participants (117 with six different immune neurodegenerative disorders 42 healthy controls) for up 20 days, whom completed regular PROs. To address walking bouts that short sparse, four feature groups...
Abstract Background Many individuals with neurodegenerative (NDD) and immune-mediated inflammatory disorders (IMID) experience debilitating fatigue. Currently, assessments of fatigue rely on patient reported outcomes (PROs), which are subjective prone to recall biases. Wearable devices, however, provide objective reliable estimates gait, an essential component health, may present evidence This study explored the relationships between gait characteristics derived from inertial measurement...
Links between cognition and walking performance in patients with Parkinson's disease (PD), which both decline progression, are well known. There is lack of knowledge regarding the predictive value for changes after individualized therapy. The aim this study to identify relevant cognitive affective parameters, measurable daily clinical routines, change quantitative early geriatric rehabilitation.Forty-seven acutely hospitalized advanced PD were assessed at baseline (T1) end (T2) a 2-week...
It is well-known that, in Parkinson's disease (PD), executive function (EF) and motor deficits lead to reduced walking performance. As previous studies investigated mainly patients during the compensated phases of disease, aim this study was investigate above associations acutely hospitalized with PD.A total seventy-four PD were assessed delta Trail Making Test (ΔTMT, TMT-B minus TMT-A) Movement Disorder Society-revised version part Unified Disease Rating Scale (MDS-UPDRS III). Walking...
Abstract Background Mobility deficits are highly prevalent among geriatric patients and have serious impact on quality of life, hospitalizations, mortality. This study aims to capture predictors mobility in hospitalized using the International Classification Functioning, Disability Health (ICF) model as a framework. Methods Data were obtained from n = 397 (78 ± 7 years, 15 ICD-11 diagnoses) ward at time admission. was assessed Short Physical Performance Battery (SPPB) total score gait,...
Individuals with heart failure (HF) frequently experience limitations in mobility, but specific aspects of these are not well understood. This study investigated the association HF severity, based on New York Heart Association (NYHA) classes, digital mobility outcomes (DMOs) and handgrip strength older inpatients HF.For this explorative analysis, hospital admission discharge data from an ongoing, prospective cohort were used. The sample included participants a sub-sample heart-healthy...
Long-term changes in health-related quality of life (HrQoL) after SARS-CoV-2 infection are common, but the causes and consequences these not well understood. HrQoL was assessed using European Quality-of-Life-5-Dimensions-5-Level-Version (EQ-5D-5L) 2,618 participants (56% female; aged 18–88 years) approximately 9 months (baseline) 26 (follow-up) their first infection. The results were compared to 40 different demographic clinical variables. A clinically important improvement noted during...
Fear of falling (FOF) negatively affects health-related quality life and is common in neurogeriatric patients, however, related parameters are not well understood. This study investigated the relationship between FOF, physical performance (as assessed with Short Physical Performance Battery its subscores) other aspects sarcopenia a sample hospitalized patients.In 124 FOF was Falls Efficacy Scale International (FES-I). measured using (SPPB) including walking duration, balance five times...
Background: Reliable estimates of frequency, severity and associated factors both fatigue cognitive impairment after COVID-19 are needed. Also, it is not clear whether the two distinct sequelae or part same syndrome. Methods: In this prospective multicenter study, frequency post-COVID were assessed in 969 patients ≥6 months SARS-CoV-2 infection with FACIT-Fatigue scale (cutoff ≤30) Montreal Cognitive Assessment (≤25 mild, ≤17 moderate impairment). matched non-COVID controls drawn from a...