A5040722741- Bacterial Infections and Vaccines
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Acute Ischemic Stroke Management
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
Vita-Salute San Raffaele University
2022-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2025
Institute of Neuroimmunology of the Slovak Academy of Sciences
2023
Coronavirus disease 2019 (COVID-19) is associated with an increased risk of thrombotic events. Ischemic stroke in COVID-19 patients entails high severity and mortality rates. Here we aimed to analyze cerebral thrombi large vessel occlusion (LVO) acute ischemic expose molecular evidence for SARS-CoV-2 the thrombus unravel any peculiar immune-thrombotic features. We conducted a systematic pathological analysis retrieved by endovascular thrombectomy LVO infected (n = 7 patients) non-covid...
Introduction: Infective endocarditis (IE) is a life-threatening condition and rare cause of ischemic stroke (IS). This study aimed to evaluate the utility analyzing cerebral thrombi, obtained through endovascular thrombectomy in IS, for pathological diagnosis IE. Patients methods: Cerebral thrombi from three groups IS patients were compared: definite IE ( n = 10), cardioembolic without with concomitant infection (CE-I − : 30, CE-I + 10). We performed histological examination, molecular...
ABSTRACT Background and Aims Infective endocarditis (IE) is a life-threatening condition known to cause stroke. Swift diagnosis antibiotic treatment are crucial for preventing cerebral systemic embolism, therefore reducing mortality morbidity. However, diagnosing IE can be challenging. In this study, we aimed assess whether analyzing thrombi retrieved by endovascular thrombectomy from stroke patients with could aid in the shed light on composition signature of endocarditic thrombi. Methods...