A5101862305- Circular RNAs in diseases
- 14-3-3 protein interactions
- Bioinformatics and Genomic Networks
- Gene Regulatory Network Analysis
- Breast Cancer Treatment Studies
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
King Abdulaziz University
2024
National Research Council Canada
2007
Biotechnology Research Institute
2007
This review article studies the complex field of noncoding RNAs (ncRNAs) in cancer biology, focusing on their potential use as biomarkers and therapeutic targets. NcRNAs include circular (circRNAs), long (lncRNAs), microRNAs (miRNAs). We discuss how ncRNAs affect gene expression cancerous cells, spread cancer, metastasis. The illustrates pathways through which can oncogenesis, tumor suppression, resistance. It also assesses clinical uses non-coding (ncRNAs), including utility diagnosis,...
Mutations or overexpression of signalling genes can result in cancer development and metastasis. In this study, we manually assembled a human cellular network developed robust bioinformatics strategy for extracting cancer-associated single nucleotide polymorphisms (SNPs) using expressed sequence tags (ESTs). We then investigated the relationships [cancer-associated SNP genes, known as (CG) cell mobility (CMGs)] context. Through graph-theory-based analysis, found that CGs are significantly...