A5103142795- Pituitary Gland Disorders and Treatments
- Advanced Measurement and Detection Methods
- Medical Research and Treatments
- Infrared Target Detection Methodologies
- Advanced Algorithms and Applications
- Advanced Neural Network Applications
- Medical Image Segmentation Techniques
- Educational Reforms and Innovations
- Vibration and Dynamic Analysis
- Image Enhancement Techniques
- Optical Systems and Laser Technology
- Advanced Decision-Making Techniques
- Educational Technology and Assessment
- Evaluation Methods in Various Fields
- Innovative Educational Techniques
- Clinical Reasoning and Diagnostic Skills
- Neuroendocrine Tumor Research Advances
- Image and Video Stabilization
- Network Security and Intrusion Detection
- Water Quality Monitoring Technologies
- Motivation and Self-Concept in Sports
- Neural Networks and Applications
- RNA Research and Splicing
- Plasma Applications and Diagnostics
- Advanced Data Storage Technologies
National Institutes of Health
2023-2025
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2023-2025
Beijing Normal University
2023
Southwest Forestry University
2016-2019
Dalian Naval Academy
2013-2019
LinkedIn (United States)
2016
Introduction Pituitary adenomas (PAs) are common, usually benign tumors of the anterior pituitary gland which, for most part, have no known genetic cause. PAs associated with major clinical effects due to hormonal dysregulation and tumoral impingement on vital brain structures. PAM encodes a multifunctional protein responsible essential C-terminal amidation secreted peptides. Methods Following identification loss-of-function variant (p.Arg703Gln) in peptidylglycine a-amidating monooxygenase...
The infrastructure beneath a worldwide social network has to continually serve billions of variable-sized media objects such as photos, videos, and audio clips. These must be stored served with low latency high throughput by system that is geo-distributed, highly scalable, load-balanced. Existing file systems object stores face several challenges when serving large objects. We present Ambry, production-quality for storing immutable data (called blobs). Ambry designed in decentralized way...
Abstract Poly(A)-binding protein (Pab1 in yeast) is involved mRNA decay and translation initiation, but its molecular functions are incompletely understood. We found that auxin-induced degradation of Pab1 reduced bulk polysome abundance WT not a mutant lacking the catalytic subunit decapping enzyme (Dcp2), suggesting enhanced decapping/degradation major driver at limiting Pab1. An increased median poly(A) tail length conferred by depletion was likewise observed dcp2Δ mutant, isoforms with...
Epigenetic reprogramming contributes to the generation of cellular diversity during vertebrate development but mechanisms directing this are still not well understood. Large-scale genetic screens have been highly successful in identifying epigenetic regulatory genes invertebrates such as worms and flies, similar large-scale identify regulators carried out vertebrates. Here we report a newly generated "EpiTag" zebrafish transgenic reporter line that permits easy cellular-level visualization...
Constructing reasonable effectiveness evaluation index system is the key step to realize scientific of equipment. In this paper, with basic ADC as a reference, concept comprehensive shipborne navigation equipment was formulated, and meaning influencing factors availability, dependability, capacity were discussed analyzed. Combined requirements weaponry for information, paper improved constructed As well-arranged, logical accessible system, it reflected objectively provided necessary...
In this paper, a region of interest (ROI) extraction algorithm based on YOLO is proposed. The optimizes the output tensor dimension model, generates different image quality images naval vessels by using degradation function, and retrains network means migration learning, which enhances accuracy detection rate algorithm. Compared with original algorithm, improved 4.25% average, proves effectiveness
The change of background's chaos feature when there are moving targets was analysed, and a new algorithm based on Lyapunov exponents image block for detection the sea surface, which is used ship proposed. method defines term gray level distance, extends calculation from single dimension signal to improved Wolf method, uses largest distance detect targetssubmerged in background. Experimental results show that surface background has feature. proposed can effectively get better result than...
The stability and persistence of web services are important to Internet companies improve user experience business performances. To keep eyes on numerous metrics report abnormal situations, time series anomaly detection methods developed applied by various departments in institutions. In this paper, we proposed a robust algorithm (MEDIFF) monitor online real time. Specifically, decomposition method using statistical metric--median--of the was decouple trend seasonal components. With effects...
In this study, an improved equipment effectiveness evaluation method based on the cloud theory was proposed to remedy deficiency in existing methods. And process designed: got index model by reverse algorithm, determined weight formula weighting method, obtained system algebraic operations, set grade of model-driven golden section ratio, results forward algorithm. This applied shipborne navigation equipment, and its simulation carried out with MATLAB software. The application proves that is...
In the past decades, PDE and 3D printing communities have developed rapidly in parallel. However, surprisingly, they very little interaction. The PDE-based technique is almost only reported combination that uses to model optimize behavior of mate-rials during process. this paper, we propose another application also bridges gap between community by 3D-printing numerical solutions for educational purposes. Specifically, apply PINN solve with initial conditions boundary conditions, export it as...
This study utilizes grounded theory methodology to conduct an in-depth analysis based on interviews with 24 sports master's students, aiming explore the enhancement pathways for academic capabilities in this demographic within China. The findings highlight several key factors affecting these capabilities: individual factors, mentorship, and environmental conditions. Specifically, graduate funding living conditions directly impact of whereas extent institutional focus level school support...
Abstract With the increase of marine and fishery activities, observation maritime object has attracted more attention. This paper introduced common methods acquisition image analysis about object, then discussed development trend with deep learning method.
Background With the increasing scale of enrollment graduate students, mental health problems postgraduates is becoming more and prominent. The traditional method education does not seem to meet needs in new media age. Mental workers colleges universities need explore ways transform challenges brought by era into opportunities. Methods paper studies opportunity challenge arrival WeChat post-graduate through literature analysis. Results results indicated that (1) lack system education; (2)...
The research is based on a kind of pitch channel hypersonic aircraft model built released by USA air force, adopting the digital simulation to verify basic free flight state preliminarily.The difference stability and divergent could get observation through result between aircraft's attitude attack angle traditional low supersonic aircraft.The aimed at evaluate rationality models, do preliminary analysis dynamic characteristics aircraft.
In order to diagnose and resolve issues occurred on navigation equipment quickly accurately, an optimal search algorithm, Hash table function a troubleshooting database of equipment, are presented.The algorithm can directly find the issue reason solution by searching address calculated from function.The average time does not increase when number record increases.This paper shows how is used in equipment.Thus, it be widely many fields.
Positive psychology and peer mutual aid is both on the basis of humanism common value essence them are to help people themselves. Therefore, based perspective positive Peer Mutual Aid representing general trend college mental health education. As an example adaptability，we have designed a comparative study method experimental group controlled group. We carried out 6 counseling activities in group, order improve adaptability does not do any intervention. Two tests were two classes before...
In order to identify the foggy weather phenomenon, this paper puts forward an automatic identification method based on k-means clustering algorithm, which analyzes effects characteristics of image gathering by sets mean value and variance extracted from saturation as feature parameters while training images are classified using algorithm obtain center different classifications; finally classification can be finished in testing phase calculating dissimilarity between center.Experimental...
For the time-vary and non-linearity of attitude stabilization system laser weapons, performances traditional adaptive control algorithms are not satisfactory. According to mathematical model loop characteristics operating conditions an approach neural network PID reference based on RBF (Radial Basis Function) on-line identification is presented. The result simulation shows that only dynamic static can satisfy index requirements, but also effect improved as compared with method.
Abstract Pituitary adenomas (PAs) are common, usually benign tumors of the anterior pituitary gland which, for most part, have no known genetic cause. PAs associated with major clinical effects due to hormonal dysregulation and tumoral impingement on vital brain structures. Following identification a loss-of-function variant (p.Arg703Gln) in PAM gene family gigantism, we investigated 299 individuals sporadic 17 familial isolated kindreds variants. encodes multifunctional protein responsible...