A5101998503- Reproductive tract infections research
- Vibrio bacteria research studies
- CRISPR and Genetic Engineering
- Syphilis Diagnosis and Treatment
- Genomics and Phylogenetic Studies
- Salmonella and Campylobacter epidemiology
- Adolescent Sexual and Reproductive Health
- Bacterial biofilms and quorum sensing
- Bacterial Infections and Vaccines
- Genital Health and Disease
- Chemical Synthesis and Analysis
- Cervical Cancer and HPV Research
- Microbial Metabolic Engineering and Bioproduction
- biodegradable polymer synthesis and properties
- Virology and Viral Diseases
- Reproductive Health and Contraception
- Polysaccharides Composition and Applications
- Menstrual Health and Disorders
- Nanoparticles: synthesis and applications
- School Health and Nursing Education
- Immune Response and Inflammation
- Antibiotic Resistance in Bacteria
- Plant-Derived Bioactive Compounds
- Bacterial Identification and Susceptibility Testing
- Nanocomposite Films for Food Packaging
Academy of Scientific and Innovative Research
2024
Institute of Microbial Technology
2023-2024
Birla Institute of Technology and Science, Pilani
2021-2024
Post Graduate Institute of Medical Education and Research
2006-2024
Motilal Nehru National Institute of Technology
2018
National Environmental Engineering Research Institute
2012-2015
University of Massachusetts Amherst
2000
Artificial proteins can be engineered to exhibit interesting solid state, liquid crystal or interfacial properties and may ultimately serve as important alternatives conventional polymeric materials. The utility of protein‐based materials is limited, however, by the availability just 20 amino acids that are normally recognized utilized biological systems; many desirable functional groups cannot incorporated directly into biosynthetic means. In this study, we incorporate para...
The CRISPR-Cas mediated regulation of biofilm by Salmonella enterica serovar Typhimurium was investigated deleting components ΔcrisprI, ΔcrisprII, ΔΔcrisprI crisprII, and Δcas op. We determined that the system positively regulates surface while inhibiting pellicle formation. Results real-time PCR suggest flagellar (fliC, flgK) curli (csgA) genes were repressed in knockout strains, causing reduced biofilm. mutants displayed altered architecture. They exhibited bacterial multilayers a denser...
We report a draft genome sequence of Alcaligenes sp. strain HPC1271, which demonstrates antimicrobial activity against multidrug-resistant bacteria. Antibiotic production by has not been frequently reported, and hence, the availability should enable us to explore new antibiotic-producing gene clusters.
The development of an accurate, sensitive, specific, rapid, reproducible, stable-at-room-temperature and cost-effective diagnostic kit, a low-cost portable fluorescence detector to fulfil the requirements facilities in developing countries.We developed 'Chlamy Ness CT/NG kit' based on molecular beacons for detection Chlamydia trachomatis (CT) Neisseriagonorrhoeae (NG). Multi-centric evaluation kit was performed using commercially available nucleic acid amplification test (NAAT)-based FTD...
Introduction: Trichomoniasis remains one of the most common sexually transmitted infections, which is curable. To prevent complications and transmission, prompt correct diagnosis essential to treat Trichomonas vaginalis . The present study was done evaluate polymerase chain reaction (PCR) with other conventional techniques for T. infection determine prevalence in women vaginal discharge based on PCR assay. Methods: Vaginal swabs were collected by trained health-care professional using...
The human immunodeficiency virus (HIV) epidemic has resulted in an increase the prevalence of many opportunistic infections and caused re-emergence certain diseases developing world. In tropical countries, immunosupression due to HIV infection changes clinical presentation endemic infections. Although immune deficiency by should presumably lead increased frequency malaria areas with malarial infection, like India, evidence association between India is scanty, only a few studies showing...
is one of the most important causative organisms in causing sexually transmitted infections. The clinical presentation gonorrhoea mimics symptoms other infections, and a proper diagnosis same therefore crucial patient management. current study intended to compare different in-house molecular methods: that is, conventional PCR, real-time LAMP assay for detection
Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are prevalent causes of sexually transmitted infections (STIs) globally, leading to substantial morbidity transmission risks.
Background Mycoplasma genitalium is implicated in genitourinary disorders both men and women as a sexually transmitted infection (STI). This study aimed to ascertain the prevalence of M. identify associated risk factors among women. Aim To investigate various risk-factors with attending clinic Western Cameroon. Methods A cross-sectional was conducted hospitals from five districts Cameroon on active non-menstruating for antenatal, prenuptial contraception consultations,between January 2020...
Abstract Several facets of the host immune response to Salmonella infection have been studied independently at great depths understand progress and pathogenesis infection. The circumstances under which a Salmonella-infected individual succumbs an active disease, evolves as persister or clears are not understood in detail. We adopted system-level approach develop continuous-time mechanistic model. considered key interactions system state variables with mesenteric lymph node determine final...
Background Bacterial vaginosis is a common vaginal syndrome among females, which leads to significant morbidity and complications, if left untreated. The association of bacterial with various sexually transmitted infections has been mentioned in previous literature. However, studies on the intermediate Nugent Score are lacking. This study was planned examine Score. Materials Methods included conducted include females presenting discharge, burning micturition, itching, lower abdominal pain...
Abstract Sustainable and intelligent solutions are required to address the issues brought about by anthropogenic activity restricted availability of resources. Every nation is attempting use each product from a natural resource in necessary way light current rise environmental awareness. The bio-based biopolymers can be made bacteria, animals, or plants. Biopolymers diverse class compounds that either produced biological systems synthesized categorized as biodegradable nonbiodegradable....
Abstract Objectives Investigating the type 1-E CRISPR-Cas-mediated regulation of Salmonella pathogenesis. Methods We assessed pathogenicity wild-type and CRISPR-Cas knockout strains using infection models. The mechanisms were elucidated antimicrobial assays expression analysis. Results defective in invasion proliferation intestinal epithelial cells macrophages. However, defects not observed Gp91 phox-/- macrophages, suggesting system’s role antioxidant defence. show hampered colonization...
Abstract CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats-CRISPR associated) system has been studied for its role in biofilm regulation and expression of outer membrane proteins Salmonella . We investigated the mediated enterica serovar Typhimurium by deleting components, ΔcrisprI , ΔcrisprII, ΔΔcrisprI crisprII, Δcas op. determined that positively regulates surface-biofilm while inhibiting pellicle-biofilm. In knockout strains, flagellar ( fliC, flgK ) curli csgA genes...
Sexually transmitted infections (STIs) are one of the most neglected diseases, leading to a high percentage morbidity and mortality in India. The World Health Organization estimated that 20% persons living with human immunodeficiency virus/acquired syndrome their 20s out twenty adolescents contract an STI each year.The present study was conducted characteristics pattern adult males prevalence various STIs among them.This retrospective by retrieving records presenting laboratory our tertiary...