A5014666945- Fungal Biology and Applications
- Medicinal plant effects and applications
- Pharmacology and Obesity Treatment
- Skin Protection and Aging
- Phytochemicals and Antioxidant Activities
- melanin and skin pigmentation
- Engineering Applied Research
- Chemical synthesis and alkaloids
- Natural Antidiabetic Agents Studies
- Advanced Physical and Chemical Molecular Interactions
- Ginseng Biological Effects and Applications
- Enzyme function and inhibition
- Microbial Metabolism and Applications
- Quantum, superfluid, helium dynamics
- Photodynamic Therapy Research Studies
- Healthcare and Venom Research
- Pharmacological Effects of Natural Compounds
- Cancer Treatment and Pharmacology
- Power Systems and Renewable Energy
- Herbal Medicine Research Studies
- Dyeing and Modifying Textile Fibers
- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- Adipokines, Inflammation, and Metabolic Diseases
- Electron and X-Ray Spectroscopy Techniques
Hoseo University
2021
Dong Wha Pharm (South Korea)
2009-2017
This study aims to evaluate the anti-obesity effects of Ashwagandha (Withania somnifera, AS), Chrysanthemum zawadskii Herbich var. latilobum (Maxim.) Kitamura (C), and their combination (AS:C = 3:1, ASC) in high-fat-diet (HFD)-induced obese animal models. Key metabolic parameters, including body weight, lipid metabolism, adipogenesis, energy expenditure, glucose homeostasis, were assessed. HFD-fed mice supplemented with AS25, C25, or ASC at different concentrations (ASC25, ASC50, ASC100)....
The medicinal mushroom Cordyceps militaris has been reported to possess anticancer and immunomodulatory effects. We investigated the immunostimulatory effects of culture supernatant C . (WIB‐801CE) by examining its in vitro enhancing on cell proliferation cytokine releases splenocytes vivo cyclophosphamide‐induced immunosuppressed mice. WIB‐801CE enhanced normal methotrexate‐induced proliferation. significantly ameliorated interleukin (IL)‐2, interferon‐γ, tumor necrosis factor‐α secretion...
This study aimed at evaluating whether Indian gooseberry (IG), barley sprout (BP), and their mixture (IGBP) could prevent obesity in vivo be used as an anti-obesity functional food. We confirmed the detection of ellagic acid saponarin, which are active components, through HPLC analysis IGBP. C57BL/6J mice were fed a 60% high-fat diet supplemented with IGBP for 15 weeks, then various analyzes (micro-CT imaging, blood analysis, H&E staining, western blot) performed. The reduced weight gain,...
A species of the fungal genus Cordyceps has been used as a complementary and alternative medicine traditional Chinese medicine, its major component cordycepin cordycepin-enriched WIB-801CE are known to have antiplatelet effects in vitro. However, it is unknown whether they also endogenous antithrombotic effects. In this study, resolve these doubts, we prepared WIB-801CE, an ethanol extract from militaris-hypha, then evaluated ex vivo, vitro Ex vivo on collagen- ADP-induced platelet...
In the present study, anti-cancer effects of ginseng fermented with Phellinus linteus (GFPL) extract were examined through in vitro and vivo assays.GFPL was produced by co-cultivating together.Ginsenoside Rg3, Rh1 Rh2 are important mediators anti-angiogenesis their levels GFPL enriched 24, 19 16 times, respectively, more than that itself fermentation.GFPL exhibited distinct effects, including growth inhibition human lung carcinoma cell line A549, promotion immune activation stimulating...
In this study, we investigated the effects of cordycepin-enriched (CE)-WIB801C, a n-butanol extract Cordyceps militaris-hypha on collagen-stimulated platelet aggregation. CE-WIB801C dose dependently inhibited collagen-induced aggregation, and had synergistic effect together with cordycepin (W-cordycepin) from inhibition stimulated phosphorylation VASP (Ser(157)) dephosphorylation PI3K Akt, binding fibrinogen to glycoprotein IIb/IIIa (αIIb/β3) release ATP serotonin in A-kinase inhibitor...
In this study, we prepared cordycepin-enriched (CE)-WIB801C, a n-butanol extract of Cordyceps militaris-hypha, and investigated the effect CE-WIB801C on collagen-induced human platelet aggregation. dose-dependently inhibited aggregation, its IC50 value was 175 μg/ml. increased cAMP level more than cGMP level, but collagen-elevated [Ca(2+)]i mobilization thromboxane A2 (TXA2) production. cAMP-dependent protein kinase (A-kinase) inhibitor Rp-8-Br-cAMPS CE-WIB801C-downregulated in dose...
UV radiation is a major factor contributing to DNA damage in skin cells, including stem cells and mesenchymal leading the depletion of these crucial cells. This study examined whether mixture Indian gooseberry barley sprout (IB) could inhibit UVB irradiation 3-isobutyl-1-methylxanthine (IBMX)-induced photoaging oxidative stress using HaCaT, Hs27, B16F10
This study investigated the protective effects of a complex Indian gooseberry and barley sprout (IB complex) on oxidative stress skin damage caused by ultraviolet B irradiation in SHK-I hairless mice. The examined impact IB hydration, wrinkle formation, melanogenesis using enzyme-linked immunosorbent assay, real-time polymerase chain reaction, western blot analysis. reduced hydration loss while also demonstrating enhanced antioxidant activities. maintained via upregulation hyaluronic acid...
Woo Jeong Ok, Gi Suk Nam, Min Ji Kim, Hyuk-Woo Kwon, Hyun-Hong Jung-Hae Shin, Deok Hwi Lim, Ho-Kyun Chang-Hwan Lee, Soo-Hak Chung, Jong-Lae and Hwa-Jin Park. BSL 2016;22:127-39. https://doi.org/10.15616/BSL.2016.22.4.127