- Pulsars and Gravitational Waves Research
- Astrophysical Phenomena and Observations
- Nerve injury and regeneration
- Gamma-ray bursts and supernovae
- Neurogenesis and neuroplasticity mechanisms
- RNA Interference and Gene Delivery
- Anesthesia and Neurotoxicity Research
- High-pressure geophysics and materials
- Advancements in PLL and VCO Technologies
- CCD and CMOS Imaging Sensors
- Radio Frequency Integrated Circuit Design
- Tendon Structure and Treatment
- Tissue Engineering and Regenerative Medicine
Sichuan University
2024
West China Hospital of Sichuan University
2024
Abstract Peripheral nerve deficits give rise to motor and sensory impairments within the limb. The clinical restoration of extensive segmental defects through autologous transplantation often encounters challenges such as axonal mismatch suboptimal functional recovery. These issues may stem from limited regenerative capacity proximal axons subsequent Wallerian degeneration distal axons. To achieve integration functions, a spatially differential plasmid DNA (pDNA) dual‐delivery nanohydrogel...
Critical peripheral nerve deficiencies present as one of the most formidable conundrums in realm clinical medicine, frequently culminating structural degradation and derangement neuromuscular apparatus. Engineered extracellular vesicles (EVs) exhibit potential to ameliorate impairments. However, advent Wallerian degeneration (WD), an inexorable phenomenon that ensues post injury, serves insurmountable impediment direct therapeutic efficacy EVs. In this investigation, we have fashioned a...