A5101553863- Glioma Diagnosis and Treatment
- Genomics and Chromatin Dynamics
- Genetic factors in colorectal cancer
- Cancer Genomics and Diagnostics
- Gastric Cancer Management and Outcomes
- Glycosylation and Glycoproteins Research
- Chromatin Remodeling and Cancer
- Epigenetics and DNA Methylation
Harbin Medical University
2012-2023
Second Affiliated Hospital of Harbin Medical University
2012-2023
Tianjin Medical University General Hospital
2012
Beijing Sanbo Brain Hospital
2012
Capital Medical University
2012
Beijing Tian Tan Hospital
2012
Glioblastomas (GBMs) containing foci that resemble oligodendroglioma are defined as GBM with component (GBMO). However, whether GBMO is a distinct clinicopathological variant of or merely represents divergent pattern differentiation remains controversial. We investigated 219 consecutive primary GBMs, which 40 (18.3%) were confirmed GBMOs. The clinical features and genetic profiles the GBMOs analyzed compared conventional GBMs. group showed more frequent tumor-related seizures (P= .027),...
The human Distal-less Homeobox (DLX) gene family encodes homeobox transcription factors involved in the control of morphogenesis and tissue homeostasis, which is primarily expressed embryonic development. Recently, DLX was reported to have essential roles carcinogenesis. We profiled whole genome genes 83 glioblastoma multiforme (GBM) patients from Chinese Glioma Genome Atlas (CGGA) Group. Two major groups samples were identified mRNA expression profiles (referred as Cluster 1 (C1) 2 (C2)). 7...
Abstract The locus at 17q12 erb‐b2 receptor tyrosine kinase 2 (ERBB2) has been heavily amplificated and overexpressed in gastric cancer (GC), but it remains to be elucidated about the clinical significance of co‐amplification co‐overexpression PGAP3 gene located around ERBB2 GC. profile four GC cell lines tissue microarrays containing 418 primary tissues was assessed investigate co‐amplified genes, evaluate impact genes on malignancy Co‐amplification accompanied with observed a haploid...