A5102271777- Probiotics and Fermented Foods
- Viral gastroenteritis research and epidemiology
- RNA modifications and cancer
- Helicobacter pylori-related gastroenterology studies
- Animal Nutrition and Physiology
- Radiopharmaceutical Chemistry and Applications
- Epigenetics and DNA Methylation
- Galectins and Cancer Biology
- Animal Virus Infections Studies
- Cancer-related gene regulation
- Monoclonal and Polyclonal Antibodies Research
- Cancer-related Molecular Pathways
- Gut microbiota and health
- Veterinary medicine and infectious diseases
- Advanced Radiotherapy Techniques
- Phytochemistry and biological activity of medicinal plants
- Rabbits: Nutrition, Reproduction, Health
- Ubiquitin and proteasome pathways
- Neurological Disease Mechanisms and Treatments
- Bone Metabolism and Diseases
- Tumors and Oncological Cases
- Drug Transport and Resistance Mechanisms
- PI3K/AKT/mTOR signaling in cancer
- Chemokine receptors and signaling
- MicroRNA in disease regulation
Taichung Veterans General Hospital
2024
Yonsei University College of Dentistry
2021-2024
Yonsei University
2021-2024
Jiangxi University of Science and Technology
2024
Jinan Stomatological Hospital
2024
Ankang City Central Hospital
2024
Aba Teachers University
2023
Guangdong Medical College
2023
Sichuan Agricultural University
2017-2022
Taipei Medical University
2020
Along with banning of antibiotics, necrotic enteritis (NE), especially subclinical NE (SNE) whereby no clinical signs are present in chicks, has become one the most threatening problems poultry industry. Therefore, increasing attention been focused on research and application effective probiotic strains, as an alternative to prevent SNE broilers. In study, we evaluated effects Lactobacillus johnsonii BS15 prevention Specifically, assessment determined growth performance indexes related...
Background: Stroke is one of the leading causes death and disability worldwide places a heavy burden on economy in our society. Current treatments, such as use thrombolytic agents, are often limited by narrow therapeutic time window. However, regeneration brain after damage still active days, even weeks, stroke occurs, which might provide second window for treatment. Emodin, traditional Chinese medicinal herb widely used to treat acute hepatitis, has been reported possess antioxidative...
Increasing studies have focused on the beneficial effects of Lactobacillus johnsonii in certain diseases. Here, we studied prevention ability a probiotic strain, L. BS15 subclinical necrotic enteritis (SNE), and its underlying mechanism. 180 male Cobb 500 chicks were randomly allotted into three groups administrated with (1 × 106 cfu/g) or Man Rogosa Sharpe liquid medium throughout 28-day experimental period. With exception normal group, SNE infection was treated for remaining period after...
In this study, we sought to evaluate purpurin, a natural biomedicine and potential inhibitor in decreasing the growth rate of lung cancer cells by modulating role PI3K/AKT signalling-associated proliferation apoptosis.A549 were treated with purpurin (30 μM) for 24 48 h incubation, respectively, it has been analysed cytotoxicity, ROS-mediated apoptotic staining. Moreover, purpurin-mediated lipid peroxidation GSH measured biochemical estimation. Furthermore, signalling-mediated cell gene...
Meat is considered as a major source of polyunsaturated fatty acid (PUFA) which essential for humans, therefore its lipid level and composition have drawn great attention. As no clinical sign can be found in chicks subclinically infected by Clostridium perfringens (CP), the meat may purchased eaten. The objective present study was to determine whether Lactobacillus johnsonii (LJ) control CP-caused impact on growth, levels, other flavor or nutritional quality meat.480 one-day-old were divided...
// Jing Lai 1,* , Weiwei Nie Wenwen Zhang 2,* Yucai Wang 3 Ruilian Xie 1 Yanru Jun Gu 4 Xu 2 Wei Song Fang Yang Guichun Huang Peng Cao 5 and Xiaoxiang Guan 1,2 Department of Medical Oncology, Jinling Hospital, School Medicine, Southern University, Guangzhou, China Nanjing Nanjing, Rutgers New Jersey School, Newark, NJ, USA General Surgery, Laboratory Cellular Molecular Biology, Jiangsu Province Institute Chinese * These authors contributed equally to this work Correspondence: Guan, email:...
Subclinical necrotic enteritis (SNE) widely outbreaks in chickens which inflicted growth-slowing, causing enormous social and economic burdens. To better understand the molecular underpinnings of SNE on lipid metabolism explore novel preventative strategies against SNE, we studied regulatory mechanism a potential probiotic, Lactobacillus johnsonii BS15 pathways involved with SNE.One hundred eighty one-day-old were randomly divided into three groups arranged basal diet (control group). Added...
Abstract A rapid, simple and inexpensive synthesis of 5‐radiohalogenated‐2′‐deoxyuridine from 5‐trimethylstannyl‐2′‐deoxyuridine is described. The total reaction purification time including thin layer chromatography (tlc) for quality control less than 30 min. This method produces excellent yields (>95%) 123 I‐, 125 131 I‐UdR. radiochemical purity all tested preparations (>20) was determined to be greater 99%. new the basis a radiolabeling kit/generator preparation radiohalogenated...
The p73 gene contains an extrinsic P1 promoter and intrinsic P2 promoter, controlling the transcription of pro-apoptotic TAp73 isoform anti-apoptotic ΔΝp73 isoform, respectively.The DNA methylation status both promoters act equally in epigenetic transcriptional regulation their relevant isoforms.The aim this study was to analyze different effects these isoforms 5aza-2'-deoxycytidine (5-aza-dC)-induced apoptosis breast cancer cells.We investigated demethylation agent, 5-aza-dC, on T-47D cell...
ABSTRACT Background oipA , an outer membrane protein of Helicobacter pylori is linked to IL‐8 induction and gastric inflammation, but its role debated due inconsistent findings. This study aims explore the phase variation in modulating virulence traits H. a bacterium strongly associated with development cancer. Material Methods American clinical isolate AH868 strain for naturally occurring variations gene, G27 vitro–induced were used elucidate 's impact on key phenotypes, including cell...
Background/Aim: To evaluate efficacy of the AIxURO system, a deep learning-based artificial intelligence (AI) tool, in enhancing accuracy and reliability urine cytology for diagnosing upper urinary tract cancers. Materials Methods: One hundred eighty-five samples were collected categorized according to The Paris System Reporting Urinary Cytology (TPS), yielding 168 negative High-Grade Urothelial Carcinoma (NHGUC), 14 atypical urothelial cells (AUC), 2 suspicious high-grade carcinoma (SHGUC),...
Transplantation of isolated hepatocytes may eventually replace a whole liver transplantation for the treatment selected metabolic disorders and acute hepatic failure. To understand behavior transplanted hepatocytes, methods longitudinal assessment functional activity survival hepatocyte transplants must be developed. Targeting asialoglycoprotein receptor (ASGPr) with various radiolabeled or Gd-labeled constructs asialofetuin (AF) is expected to allow noninvasive quantitative assessments...
Giant pandas are uniquely vulnerable mammals in western China. It is important to develop an animal model explore the intestinal flora of giant understand relationship between digestive diseases and flora. Existing models focus on human flora-associated animals, such as mice, there a very limited amount knowledge regarding panda animals. To fill this gap, fecal microorganisms from were transplanted into pseudosterile germfree mice using single multiple gavages. Fecal samples collected at...