A5010705489- Animal Nutrition and Physiology
- Pharmacological Effects of Natural Compounds
- Crystallization and Solubility Studies
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Gut microbiota and health
- Rabbits: Nutrition, Reproduction, Health
- Selenium in Biological Systems
- Antimicrobial Resistance in Staphylococcus
- Probiotics and Fermented Foods
- Livestock and Poultry Management
- Antioxidant Activity and Oxidative Stress
- Salmonella and Campylobacter epidemiology
- Antimicrobial Peptides and Activities
- Viral gastroenteritis research and epidemiology
- Drug Solubulity and Delivery Systems
- Adipose Tissue and Metabolism
- Chemical Thermodynamics and Molecular Structure
- Chemical and Physical Properties in Aqueous Solutions
- Antibiotics Pharmacokinetics and Efficacy
- Trace Elements in Health
- Aquaculture disease management and microbiota
- Genomics, phytochemicals, and oxidative stress
- Heavy Metal Exposure and Toxicity
- Coccidia and coccidiosis research
Sichuan Agricultural University
2016-2025
Anhui Medical University
2024
Anhui Institute of Architectural Research and Design
2024
First Affiliated Hospital of Anhui Medical University
2024
South China Agricultural University
2021
Shanghai Veterinary Research Institute
2019
Chengdu University
2018
Biofilm-associated lung infections, particularly those caused by Staphylococcus aureus (S. aureus), pose significant clinical challenges to conventional therapies. S. Biofilm infections are refractory treatment due the presence of persister bacterial cells and barrier effect unique extracellular polymeric substances (EPS). This study describes development multifunctional micelles, HK-SL Ms, utilizing sophorolipid (SL) encapsulate Honokiol (HK). Ms potently disrupted EPS barrier, killed some...
The aim of this study was to investigate the possible protective role sodium selenite on aflatoxin B1-induced oxidative stress and apoptosis in spleen broilers. Two hundred one-day-old male broilers, divided into five groups, were fed with basal diet (control group), 0.3 mg/kg AFB1 (AFB1 + 0.2 Se (+Se group I), 0.4 II) 0.6 III), respectively. According biochemical assays, significantly decreased activities glutathione peroxidase, total superoxide dismutase, reductase, catalase level hormone,...
Hepatic oxidative stress, as one important mechanism of cadmium (Cd)-induced hepatic toxicity, could, known, be ameliorated by vitamin E (VE). However, the underlying remains to elucidated. To investigate whether antioxidant can protect against Cd-induced sub-chronic liver injury associated with stress and nuclear factor erythrocyte 2-related 2 (Nrf2) pathway, male Sprague-Dawley rats (nine-week-old) were randomly divided into four groups (eight rats/group), namely, control, VE (100 mg/kg...
The antioxidant effect of salidroside has been proven, but its role in liver injury is poorly understood. In this study, we aimed to evaluate the protective effects and mechanism on induced by carbon tetrachloride (CCl4) vivo. Mice were pretreated with (60 mg/kg, intraperitoneally injected, i.p.) once per day for 14 consecutive days then administered CCl4 (15.95 g/kg, 24 h produce a model. Salidroside attenuated hepatic transaminase elevation serum ameliorated steatosis necrosis, thereby...
Laying hens experience a rapid decline in egg production, quality, and immunity, usually at the end of peak laying period. Quercetin, known flavonoid, exerts biological activities, including phytoestrogenic, antibiotic, antioxidant, anti-inflammatory properties. Vitamin E also shows production immunoregulatory potential animals. This study evaluated capacity dietary quercetin, vitamin E, combination both, to promote improve immunity aging breeder hens. We elucidated how quercetin could...
The fertility of female animals is negatively correlated with increasing chronological age. In aging broiler breeder hens, there a decline in the functionality ovary and liver accompanied by hormonal or endocrine changes, reduction antioxidant capacity, decrease folliculogenesis. Therefore, improving reproductive function hens using dietary strategies great concern to poultry breeder. This study evaluated capacity quercetin (Q), vitamin E (VE), their combination (Q + VE) promote follicle...
Biological ornaments, such as the comb in chickens, act condition-dependent indicators of mate quality and are influenced by genetic, hormonal, environmental factors. In this study, we investigated histomorphological development combs Sichuan Mountaineous Black-bone chickens examined their relationship with growth performance hormone levels. At market age, were classified into large- small-comb groups based on size, skeletal traits, slaughter performance, meat evaluated. The results showed...
Pseudorabies virus (PRV) is a pathogen of swine resulting in devastating disease and economic losses worldwide. Resveratrol (Res) exhibits inhibitory activity against wide range viruses. Despite these important advances, the molecular mechanism(s) by which Res exerts its broad biological effects have not yet been elucidated. In this paper, antiviral PRV mechanism action were investigated. The results showed that potently inhibited replication dose-dependent manner, with 50% inhibition...
To explore AFB1-induced damage of the small intestine, changes in structure and expression TLRs (Toll-like Receptors) intestine chickens were systematically investigated. Ninety healthy neonatal Cobb randomized into a control group (0 mg/kg AFB1) an AFB1 (0.6 AFB1). The crypt depth was significantly increased comparison to chickens, while villus height area evidently decreased, as well villus:crypt ratio epithelial thickness. histopathological observations showed that villi exposed obviously...
With continuous emergence and widespread of multidrug-resistant Staphylococcus aureus infections, common antibiotics have become ineffective in treating these infections the clinical setting. Anti-virulence strategies could be novel, effective therapeutic against drug-resistant bacterial infections. Sortase A (srtA), a transpeptidase gram-positive bacteria, can anchor surface proteins that play vital role pathogenesis bacteria. SrtA is known as potential antivirulent drug target to treat In...
Context: Methicillin-resistant Staphylococcus aureus (MRSA) is a very harmful bacterium. Oridonin, component in Rabdosia rubescens (Hemsl.) Hara (Lamiaceae), widely used against bacterial infections China. Objective: We evaluated oridonin effects on MRSA cell membrane and wall, protein metabolism, lactate dehydrogenase (LDH), DNA microscopic structure. Materials methods: Broth microdilution flat colony counting methods were to measure minimal inhibitory concentration (MIC) minimum...