Li‐Jen Chang

ORCID: 0000-0003-0827-5271
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About
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Research Areas
  • Veterinary Pharmacology and Anesthesia
  • Pharmacological Effects of Natural Compounds
  • Drug-Induced Hepatotoxicity and Protection
  • Antibiotic Resistance in Bacteria
  • Anesthesia and Pain Management
  • Hydrological Forecasting Using AI
  • Bioactive Compounds and Antitumor Agents
  • Selenium in Biological Systems
  • 2D Materials and Applications
  • Arsenic contamination and mitigation
  • Ginger and Zingiberaceae research
  • Perovskite Materials and Applications
  • Antimicrobial agents and applications
  • Lipid metabolism and disorders
  • Stroke Rehabilitation and Recovery
  • Water Quality Monitoring Technologies
  • Animal Nutrition and Physiology
  • Microbial Metabolism and Applications
  • Gut microbiota and health
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Fullerene Chemistry and Applications
  • Pharmacological Effects and Assays
  • Veterinary Equine Medical Research
  • Wound Healing and Treatments
  • Trace Elements in Health

Virginia–Maryland College of Veterinary Medicine
2023-2024

Chia-Yi Christian Hospital
2024

Oklahoma State University
2021-2022

Purdue University West Lafayette
2021

National Yang Ming Chiao Tung University
2017

Industrial Technology Research Institute
2017

United States Military Academy
2010

National Dong Hwa University
2008

National Taiwan University
2002

Abstract Defects and their spatial distribution are crucial factors in controlling the electronic optical properties of semiconductors. By using scanning transmission electron microscopy energy loss spectroscopy, type impurities/defects WS 2 subdomains with different is successfully assigned. A higher population Cr impurities found W‐terminated edge domain, while S‐terminated domain contains more Fe impurities, accordance luminescence characteristics chemical‐vapor‐grown a hexagonal shape....

10.1002/adfm.201704210 article EN Advanced Functional Materials 2017-11-30

Lipopolysaccharide (LPS) has been considered the primary agent to establish animal models of inflammation, immunological stress, and organ injury. Previous studies have demonstrated that LPS impaired gastrointestinal development disrupted intestinal microbial composition metabolism. Ferulic acid (FA) isolated from multiple plants exhibits biological activities. This study investigated whether FA ameliorated function microflora in LPS-challenged Tianfu broilers. The results showed challenge...

10.3390/molecules28041720 article EN cc-by Molecules 2023-02-10

Lipopolysaccharide (LPS) is an endotoxin that can cause imbalance between the oxidation and antioxidant defense systems then induces hepatic damages. Ferulic acid (FA) has multiple biological functions including antibacterial activities; however, effect of FA on lipopolysaccharide-induced injury remains unknown. The purpose this study was to investigate mechanism action dietary against Lipopolysaccharide-induced injuries in Tianfu broiler chickens. results showed supplementation daily feed...

10.3390/toxins14030227 article EN cc-by Toxins 2022-03-21

The aim of this study was to explore the association between antimicrobial resistance, ESBL genes, and virulence genes Salmonella isolates. From 2019 2021, a total 117 isolates were obtained from symptomatic chickens in Sichuan Province, China. strains tested for resistance presence according Clinical Laboratory Standards Institute (CLSI) instructions. determined using Polymerase Chain Reaction (PCR). In addition, Multilocus Sequence Typing (MLST) applied confirm molecular genotyping....

10.3390/ani13172770 article EN cc-by Animals 2023-08-31

Cadmium (Cd) is known as a highly toxic heavy metal and has been reported to induce hepatotoxicity in animals. Nano-selenium (NSe) an antioxidant that plays many biological roles such oxidative stress alleviation. The purpose of this study explore the mechanism action by which NSe inhibits Cd-induced hepatic toxicity stress. Sixty eight-week-old male Kunming mice were randomly divided into four groups (15 per group). control group cadmium received distilled water, whereas sodium-selenite 0.2...

10.3389/fvets.2022.942189 article EN cc-by Frontiers in Veterinary Science 2022-07-26

Abstract Background Catharanthus roseus, a Madagascar native flowering plant, is known for its glossy leaves and vibrant flowers, medicinal significance due to alkaloid compounds. As source of vinblastine vincristine used in chemotherapy, roseus also employed traditional medicine with flower stalks dried form. Its toxicity can lead various adverse effects. We report case juice presenting as acute cholangitis, emphasizing the importance healthcare providers obtaining detailed herbal...

10.1186/s12906-024-04441-1 article EN cc-by BMC Complementary Medicine and Therapies 2024-04-04

The aim of this study was to investigate the effects adding tea tree oil (TTO) in basal diet on growth performance, immune function, and intestinal function broilers. This utilized 1,650 one-day-old broilers with good health similar body weight. Subjects were randomized into 5 groups 6 replicates each: control group (CON, diet), positive (PCG, + 100 mg/kg oregano low-dose TTO (TTO-L, 50 added medium-dose (TTO-M, high-dose (TTO-H, 200 diet). whole test period lasted 28 d. results showed that...

10.1016/j.psj.2023.102936 article EN cc-by-nc-nd Poultry Science 2023-07-15

Escherichia coli (E. coli) plays an important ecological role, and is a useful bioindicator to recognize the evolution of resistance in human, animal environment. Recently, extended-spectrum β-lactamases (ESBL) producing E.coli has posed threat public health. Generally, captive healthy giant pandas are not exposed antibiotics; however, they still acquire antimicrobial resistant bacteria. In order understand whether there exchange genes within ecosystems pandas, this study explored...

10.1016/j.ecoenv.2024.116395 article EN cc-by Ecotoxicology and Environmental Safety 2024-05-09

Aristolochic acid (AA) is a component of traditional Chinese herbs and commonly used for farm animals in China. Over-exposure AA has been proven to be associated with hepatotoxicity; however, the mechanism action AA-I-induced hepatotoxicity remains unknown. In current study, subchronic toxicity test was conducted evaluate AA-induced Tianfu broilers. According results, broilers evidenced by elevation liver weight, levels serum glutamic oxalacetic transaminase (GOT) glutamic-pyruvic (GPT)....

10.3390/ani11123437 article EN cc-by Animals 2021-12-02

Abstract OBJECTIVE To evaluate and compare the anesthetic, analgesic, cardiorespiratory effects of tiletamine-zolazepam-detomidine-butorphanol (TZDB), tiletamine-zolazepam-xylazine-butorphanol (TZXB), ketamine-detomidine-butorphanol (KDB) in pigs to assess anesthetic recovery duration quality following administration tolazoline as a reversal agent. ANIMALS 11 healthy 2.5-month-old castrated male Landrace mixed-breed pigs. PROCEDURES In randomized, blinded crossover study design, received...

10.2460/javma.258.8.883 article EN Journal of the American Veterinary Medical Association 2021-04-07

Hemorheology and blood glucose are commonly used to estimate the risks of thrombosis stress hyperglycemia after anaesthesia. The sequence acupoint stimulation might influence therapeutic effects acupuncture. In current study, we aimed at investigating effect different acupuncture sequences "

10.1016/j.heliyon.2024.e25497 article EN cc-by-nc-nd Heliyon 2024-01-30

The weak second harmonic light generating from carbon nanotubes are detected. signal intensity closely related to the density of pi-bonds attributed defects in rolled graphene sheets, which is stimulated have anharmonic oscillation as strongly affected by environment. intensities SHG diminished order well-aligned multi-wall (MWCNTs), randomly-aligned MWCNTs, and then single-wall CNTs.

10.1166/jnn.2008.101 article EN Journal of Nanoscience and Nanotechnology 2008-06-01

The excessive intake of fluoride, one the trace elements required to maintain health, leads liver injury. Tetramethylpyrazine (TMP) is a kind traditional Chinese medicine monomer with good antioxidant and hepatoprotective function. aim this study was investigate effect TMP on injury induced by acute fluorosis. A total 60 1-month-old male ICR mice were selected. All randomly divided into five groups: control (K) group, model (F) low-dose (LT) medium-dose (MT) high-dose (HT) group. groups...

10.3390/molecules28124849 article EN cc-by Molecules 2023-06-19
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