Madison Frazier
A5062240646- Pain Management and Placebo Effect
- Acupuncture Treatment Research Studies
- Parasitic Diseases Research and Treatment
- Complementary and Alternative Medicine Studies
- Pharmacological Receptor Mechanisms and Effects
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Health and Well-being Studies
- Healthcare and Venom Research
- Radiopharmaceutical Chemistry and Applications
- Pharmacy and Medical Practices
- Epilepsy research and treatment
- Telomeres, Telomerase, and Senescence
- COVID-19 and Mental Health
- Schizophrenia research and treatment
- Intensive Care Unit Cognitive Disorders
- Medical Imaging Techniques and Applications
- Genetics, Aging, and Longevity in Model Organisms
- CRISPR and Genetic Engineering
- Parasites and Host Interactions
- Radiation Detection and Scintillator Technologies
Duke University
2025
Institute of Accelerating Systems and Applications
2022-2023
Morehead State University
2021
The effectiveness of ivermectin to shorten symptom duration or prevent hospitalization among outpatients in the US with mild moderate symptomatic COVID-19 is unknown.To evaluate efficacy ivermectin, 400 μg/kg, daily for 3 days compared placebo treatment early COVID-19.ACTIV-6, an ongoing, decentralized, double-blind, randomized, placebo-controlled platform trial, was designed repurposed therapies COVID-19. A total 1591 participants aged 30 years and older confirmed COVID-19, experiencing 2...
Importance The effectiveness of fluvoxamine to shorten symptom duration or prevent hospitalization among outpatients with mild moderate symptomatic COVID-19 is unclear. Objective To evaluate the efficacy low-dose (50 mg twice daily) for 10 days compared placebo treatment in US. Design, Setting, and Participants ongoing Accelerating Therapeutic Interventions Vaccines (ACTIV-6) platform randomized clinical trial was designed test repurposed medications COVID-19. A total 1288 participants aged...
It is unknown whether ivermectin, with a maximum targeted dose of 600 μg/kg, shortens symptom duration or prevents hospitalization among outpatients mild to moderate COVID-19.
Study objectiveAcute musculoskeletal pain in emergency department (ED) patients is frequently severe and challenging to treat with medications alone. The purpose of this study was determine the feasibility, acceptability, effectiveness adding ED acupuncture acute episodes neck, back, extremities.MethodsIn pragmatic 2-stage adaptive open-label randomized clinical trial, Stage 1 identified whether auricular (AA; based on battlefield protocol) or peripheral (PA; needles head, extremities only),...
Objective Acupuncture is an evidence-based pain treatment in clinic settings, but its optimal delivery has not been established emergency departments (EDs). As part of adaptive pragmatic randomized controlled trial ED acupuncture for acute musculoskeletal (NCT04290741), we embedded a qualitative evaluation acceptability and suggestions improvement from study participants receiving the ED. Methods Semi-structured interviews conducted remotely evaluated factors impacting patients’...
Telomerase is a ribonucleoprotein enzyme complex that maintains telomeres at the ends of linear eukaryotic chromosomes. minimally requires telomerase reverse transcriptase (TERT) protein uses non-coding RNA as template to extend 3ʹ lagging strands. In addition binding TERT and providing template, plays additional roles in accessory proteins contributing catalysis. RNAs are rapidly evolving length, sequence structure, making phylogenetic comparisons challenging limiting our understanding...