- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Fungal and yeast genetics research
- Plant nutrient uptake and metabolism
- Biofuel production and bioconversion
- 3D Printing in Biomedical Research
- Cancer Cells and Metastasis
- Cancer Immunotherapy and Biomarkers
- Mesenchymal stem cell research
Vrije Universiteit Amsterdam
2023-2024
Amsterdam University Medical Centers
2023
Dutch Blood Transfusion Society
1995
University of Amsterdam
1987-1995
A new monoclonal antibody, MOMA-2, is described, which recognizes monocytes and macrophages in the mouse. The antibody reacts with majority of mononuclear phagocytes various tissues as determined by immunohistochemistry. It differs from other macrophage markers that have been described strong reaction lymphoid organs such tingible body T cell-dependent areas. predominantly a cytoplasmic component, although membrane component can also be demonstrated. Isolated Langerhans' cells,...
Abstract CD27, a member of the TNFR family, is expressed on most but not all peripheral blood CD4+ T cells. The small fraction cells with CD27- phenotype exclusively reside within CD45RA-CD45RO+ subset. We previously provided evidence that are functionally differentiated have lost CD27 expression as result persistent antigenic stimulation. here show compared CD4+CD45RA-CD27+ cells, CD4+CD45RA-CD27- lymphocytes high beta 1 integrins VLA-4 and -5 2 integrin CD11b. Molecules implicated in...
S. cerevisiae (or budding yeast) is an important micro-organism for sucrose-based fermentation in biotechnology. Yet, it largely unknown how yeast adapts to sucrose transitions. Sucrose can only be metabolized when the invertase or maltose machinery are expressed and we propose that Gpr1p receptor signals extracellular availability via cAMP peak adapt cells accordingly. A transition glucose gave a transient which was maximally induced sucrose. When transitioned sucrose, signalling mutants...
Since small intestine is one of the major barriers human body, there a need to develop reliable in vitro intestinal models. These models should incorporate both epithelial and lamina propria compartments have similar barrier properties compared that tissue. are essential for various applications, such as studying cell-cell interaction, diseases testing permeability metabolism drugs other compounds. The contains multiple stromal cell populations with several important functions, secretion...
Abstract S. cerevisiae (or budding yeast) is an important micro-organism for sucrose-based fermentation in biotechnology. Yet, it largely unknown how yeast adapts to sucrose transitions. Sucrose can only be metabolized when the invertase or maltose machinery are expressed and we propose that Gpr1p receptor signals extracellular availability via cAMP peak adapt cells accordingly. A transition glucose gave a transient which was maximally induced sucrose. When transitioned sucrose, signalling...