A5040105292- Ultrasound in Clinical Applications
- Atmospheric and Environmental Gas Dynamics
- Smart Grid and Power Systems
- Power Systems and Renewable Energy
- Advanced MRI Techniques and Applications
- Hybrid Renewable Energy Systems
- Methane Hydrates and Related Phenomena
- Tracheal and airway disorders
- Power Systems and Technologies
- Cardiac Imaging and Diagnostics
- Vascular Anomalies and Treatments
- Cerebrovascular and genetic disorders
University of California, San Francisco
2024
University of San Francisco
2024
North China Electric Power University
2024
Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant vascular disorder with manifestations including severe nose bleeding and microhemorrhage in brains. Despite being the second most common inherited disorder, pathophysiological mechanism underlying HHT-associated hemorrhage poorly understood. HHT pathogenesis thought to follow a Knudsonian two-hit model, requiring somatic mutation for lesion formation. Mutations activin receptor-like kinase 1 ( ALK1 ) gene cause type 2. We...