A5036878429- Malaria Research and Control
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- SARS-CoV-2 and COVID-19 Research
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Single-cell and spatial transcriptomics
- Respiratory Support and Mechanisms
- Trauma and Emergency Care Studies
- Molecular Biology Techniques and Applications
- Stress Responses and Cortisol
- Viral gastroenteritis research and epidemiology
- Insect symbiosis and bacterial influences
- SARS-CoV-2 detection and testing
- Cancer Genomics and Diagnostics
- Biosensors and Analytical Detection
- CRISPR and Genetic Engineering
- Dermatology and Skin Diseases
Griffith University
2024
Queensland Health
2020-2022
Queensland Government
2021
Scientific Services
2020
The University of Queensland
2016
On the 26th of November 2021, World Health Organization (WHO) designated newly detected B.1.1.529 lineage severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron Variant Concern (VOC). The genome VOC contains more than 50 mutations, many which have been associated with increased transmissibility, differing disease severity, and potential to evade immune responses developed for previous VOCs such as Alpha Delta. In days since designation a VOC, infections reported in countries...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of COVID-19, is a readily transmissible and potentially deadly pathogen which currently re-defining human susceptibility to pandemic viruses in modern world. The recent emergence several genetically distinct descendants known as variants concern (VOCs) further challenging public health disease management, due increased rates virus transmission potential constraints on vaccine effectiveness. We report...
West Nile virus, Kunjin strain (WNVKUN) is endemic in Northern Australia, but rarely causes clinical disease humans and horses. Recently, WNVKUN genomic material was detected cutaneous lesions of farmed saltwater crocodiles (Crocodylus porosus), live virus could not be isolated, begging the question pathogenesis these lesions. Crocodile hatchlings were experimentally infected with either 105 (n = 10) or 104 11) TCID50-doses each group co-housed six uninfected a mosquito-free facility. Seven...
The Kunjin strain of West Nile virus (WNVKUN) is a mosquito-transmitted flavivirus that can infect farmed saltwater crocodiles in Australia and cause skin lesions devalue the hides harvested animals. We implemented surveillance system using honey-baited nucleic acid preservation cards to monitor WNVKUN another endemic pathogen, Murray Valley encephalitis (MVEV), on crocodile farms northern Australia. traps were set between February 2018 July 2020 three Darwin (Northern Territory) one Cairns...
We briefly describe a method to inoculate susceptible cell line with human patient sample in order culture the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cause of disease, COVID-19. Clinical samples including nasopharyngeal swabs and aspirates were inoculated onto confluent monolayers African green monkey kidney Vero C1008, clone E6 cells (ATCC®-CRL-1586) grown Opti-Mem reduced serum growth medium supplemented 3% foetal bovine polystyrene, flat-sided, screw-cap 3 mL tubes....
The emergence of spatial profiling technologies in recent years has accelerated opportunities to profile detail the molecular attributes a wide range tissue pathologies using archival specimens. However, treatment for fixation and storage does not always support generation high-quality genomic data. purpose this study was investigate impacts Proteinase K (ProtK) treatment, as way increase target transcript exposure, on downstream sequencing data quality metrics transcriptomic formalin-fixed,...
Abstract The dengue viruses (DENVs) occur throughout tropical and subtropical regions of the world where they infect 100s millions people annually. In Australia, receptive zone is confined to northern state Queensland principal vector Aedes aegypti (L.) present. current study, two populations Ae. from north were exposed urban outbreak strains one sylvatic strain virus type 2 (DENV-2). titer required 50% mosquitoes was between 105 106 tissue culture infectious dose (TCID)50/ml influenced by...