A5018718158- Neuropeptides and Animal Physiology
- Comparative Animal Anatomy Studies
- Animal Nutrition and Physiology
- Parasites and Host Interactions
- Immune Response and Inflammation
- Immune Cell Function and Interaction
- Genetic and phenotypic traits in livestock
- Cardiac Valve Diseases and Treatments
- Cytokine Signaling Pathways and Interactions
- Effects of Environmental Stressors on Livestock
- Coccidia and coccidiosis research
- Neurobiology and Insect Physiology Research
- Veterinary Equine Medical Research
- Helicobacter pylori-related gastroenterology studies
- Milk Quality and Mastitis in Dairy Cows
- Animal health and immunology
- Mollusks and Parasites Studies
- Receptor Mechanisms and Signaling
- Glycosylation and Glycoproteins Research
- 3D Printing in Biomedical Research
- Research on Leishmaniasis Studies
- Monoclonal and Polyclonal Antibodies Research
- Animal testing and alternatives
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Congenital Heart Disease Studies
Kyoto University of Advanced Science
2024
Azabu University
2017
Montreal Neurological Institute and Hospital
2009
Yamagata University
1987-1998
Obihiro University of Agriculture and Veterinary Medicine
1972-1994
Hiroshima University
1963
Summary Endocrine cells immunoreactive for somatostatin, gastrin, glicentin, glucagon, secretin, cholecystokinin, motilin and neurotensin were identified immunocytochemically in the gastrointestinal mucosa of horse. Somatostatin‐, glicentin‐and glucagon‐immunoreactive very numerous cardiac fundic regions stomach, whereas most gastrin‐immunoreactive confined to pyloric region. Somatostatin‐immunoreactive also detected all portions small intestine while exclusively upper portion...
Recent studies on neutrophils have revealed that these cells produce various cytokines, and may be involved in regulation of the immune response. We examined whether are delayed type hypersensitivity (DTH) to SRBC rats by selective depletion vivo using a mAb designated RP-3. When had been treated with RP-3 at time priming SRBC, DTH was inhibited. Furthermore, treatment effective inhibiting effector phase response SRBC. spleen from immunization were used for local transfer DTH, footpad...
We demonstrated in our previous paper that treatment of rats with RP-3, a mAb depletes vivo neutrophils selectively, resulted inhibition both the priming and effector phases delayed type hypersensitivity (DTH) to SRBC. In order clarify mechanisms this phenomenon, we examined effect RP-3 on mononuclear leukocyte (MNL) recruitment DTH. When had been treated at time Ag priming, MNL migration, which accompanies DTH, was inhibited. The prior infiltration also partially required for because...
Abstract The distribution of nerves containing immunoreactivity for substance P (SP), vasoactive intestinal polypeptide (VIP), leucine‐enkephalin (LENK), gastrin‐releasing (GRP), and somatostatin (SOM) was studied in the reticulorumen reticular groove calf cow, use immunohistochemistry. Neuron‐specific enolase (NSE) antiserum used to determine general nerves, which then compared immunoreactive (IR) stained five kinds peptides. Nerve fibers cell bodies were observed all segments examined;...
The occurrence and distribution of endocrine cells in the gastrointestinal tract lesser mouse deer, <i>Tragulus javanicus</i> were studied immunohistochemically. Fourteen types immunoreactive for serotonin, somatostatin, enteroglucagon, pancreatic glucagon, bovine polypeptide (BPP), gastrin, substance P, motilin, gastric inhibitory (GIP), cholecystokinin (CCK), methionine-enkephalin-Arg<sup>6</sup>-Gly<sup>7</sup>-Leu<sup>8</sup> (MENK-8),...
Abstract We previously demonstrated that selective depletion of polymorphonuclear neutrophils by a mAb inhibits both the priming and effector phases delayed-type hypersensitivity (DTH) to SRBC. To better understand role in DTH, we examined effect granulocyte CSF (G-CSF) on DTH SRBC mice. G-CSF administered at elicitation phase enhanced response was weak control G-CSF-untreated This treatment also augmented mononuclear leukocyte recruitment these However, administration failed augment under...
The distribution in the sheep omasum of peptide- and catecholamine-containing neurons was investigated by an immunohistochemical technique using antibodies against six neuropeptides two catecholamine-synthesizing enzymes. In myenteric plexus, both nerve cell bodies fibers were positively immunostained for substance P (SP), methionine enkephalin (ENK), vasoactive intestinal polypeptide (VIP), neuropeptide Y (NPY) galanin (GAL). contrast, immunoreactivity specific calcitonin gene-related...
Background Although the concept that an initial course of immune-suppression facilitates subsequent immune-modulation (such as Th1 to Th2 deviation) is attractive for several autoimmune diseases, such a mechanism serial-combination therapy has never been formally demonstrated. Recently, brief mitoxantrone induction-chemotherapy followed by with glatiramer acetate (GA) was significantly more effective at reducing multiple sclerosis disease activity than GA alone. Objective To examine whether...
The electron immunocytochemical co-localization of prochymosin and pepsinogen in chief cells, mucous neck cells transitional neck/chief calf fundic glands was studied using specific antisera for with a protein A-gold method. Prochymosin immunoreactivities were detected the same secretory granules chief, simultaneously small large colloidal gold particles. In both distributed uniformly over zymogen showing round, large, homogeneous electron-dense appearance. found exclusively on core located...
Abstract The distribution of nerves containing immunoreactivity for substance P (SP), vasoactive intestinal polypeptide (VIP), leucine‐enkephalin (LENK), and gastrin‐releasing (GRP) in the margin reticulo‐omasal orifice, omasum, omasal pillar calves cows was studied by immunohistochemistry. general determined means neuron‐specific enolase (NSE) antiserum then compared to immunoreactive (IR) stained four peptides. Marked differences were associated with age segment examined. SP‐IR fibers...
Summary The mucosal relief of the omasum in cattle, sheep and goats was examined by naked eye, stereoscopic microscope scanning electron microscope. showed wide variations both between within these species. Omasal papillae on laminae varied highly shape, i. e. conical, rounded, claw‐like, wart‐like, finger‐like etc. They decreased gradually size from oral to aboral region omasal lamina. Ridge‐like structures linear arrangements were also seen cattle sheep. Many grooves folds found lateral...
The presence of gastricsin in bovine abomasal juice has been reported previously, but its exact site origin not yet established. Specific polyclonal antibodies were used the peroxidase-antiperoxidase method or protein A/gold technique to label cells producing progastricsin. This immunocytolocalization was correlated with that pepsinogen and prochymosin using specific against those zymogens. present study clearly established progastricsin located exclusively chief, mucous neck, transitional...