A5037374596- Cerebral Palsy and Movement Disorders
- Hip disorders and treatments
- Orthopedic Surgery and Rehabilitation
- Neurogenetic and Muscular Disorders Research
- Balance, Gait, and Falls Prevention
- Bone fractures and treatments
- Elbow and Forearm Trauma Treatment
- Botulinum Toxin and Related Neurological Disorders
- Shoulder Injury and Treatment
- Intellectual Property Law
- Family and Disability Support Research
- Lower Extremity Biomechanics and Pathologies
- Digital Games and Media
- Stroke Rehabilitation and Recovery
- Hip and Femur Fractures
- Diabetic Foot Ulcer Assessment and Management
- Injury Epidemiology and Prevention
- Musculoskeletal Disorders and Rehabilitation
- Scoliosis diagnosis and treatment
- Educational Games and Gamification
- Orthopedic Infections and Treatments
- Child and Adolescent Health
- Foot and Ankle Surgery
- Neonatal and fetal brain pathology
- Muscle activation and electromyography studies
University of Saskatchewan
2025
University of Bristol
2024
University of South Florida
2024
Royal Hospital for Children
2004-2023
Queen Mary University of London
2022
University of Ontario Institute of Technology
2013-2021
University of St Andrews
2007-2021
Andrews University
2019
Astley Ainslie Hospital
2010-2016
Science Applications International Corporation (United States)
2013
Genome-wide association studies have identified thousands of loci for common diseases, but, the majority these, mechanisms underlying disease susceptibility remain unknown. Most associated variants are not correlated with protein-coding changes, suggesting that polymorphisms in regulatory regions probably contribute to many phenotypes. Here we describe Genotype-Tissue Expression (GTEx) project, which will establish a resource database and tissue bank scientific community study relationship...
Complex gait analysis systems are not generally available worldwide, and no simple system of assessing by observation has been validated specifically for use in patients with cerebral palsy. The authors have developed a visual score Videotaped sequences were recorded before after surgery as part three-dimensional study using Vicon (Oxford, U.K.) system. demonstrated good intraobserver interobserver reliability. numeric values the elements correlated well measurements obtained from...
Bone cells respond to mechanical stimuli, but the transduction mechanisms responsible are not fully understood. Integrins, a family of heterodimeric transmembrane glycoproteins, which link components extracellular matrix with actin cytoskeleton, have been implicated as mechanoreceptors. We assessed roles integrins in cyclical stimuli human bone (HBCs), results changes membrane potential. HBC showed depolarization following 0.104 Hz stimulation and hyperpolarization at 0.33 Hz. The response...
In a prospective, randomised controlled trial, 68 children who had completely displaced metaphyseal fracture of the distal radius were treated either by manipulation (MUA) and application an above-elbow cast alone or additional insertion percutaneous Kirschner (K-) wire. Full radiological follow-up to union was obtained in 65 56 returned for clinical evaluation three months after injury. Maintenance reduction significantly better K-wire group fewer radiographs required. There no significant...
Complex gait analysis systems are not generally available worldwide, and no simple system of assessing by observation has been validated specifically for use in patients with cerebral palsy. The authors have developed a visual score Videotaped sequences were recorded before after surgery as part three-dimensional study using Vicon (Oxford, U.K.) system. demonstrated good intraobserver interobserver reliability. numeric values the elements correlated well measurements obtained from...
Recent reports have suggested that a delay in the management of type-III supracondylar fractures humerus does not affect outcome. In this retrospective study we examined whether timing surgery affected peri-operative complications, or need for open reduction. There were 171 children with closed fracture and no vascular compromise our study. They divided into two groups: those treated less than eight hours from presentation to Accident Emergency Department (126 children), more (45 children)....
This study was designed to assess the impact of gait analysis on treatment patients with cerebral palsy. One hundred two ambulant palsy were assessed clinically and analysis. Separate proposals for each patient recorded after clinical examination The results methods assessment compared. After assessment, 71 102 evaluated recommended a surgical procedure 31 nonoperative treatment. analysis, indications confirmed in 91 cases (89%). Clinical by same orthopedic surgeon close agreement...
In the workplace, an individual's punctuality will not only affect how a person is viewed by colleagues, but also reverberate on their productivity. Being late for meeting can be disruptive to working team, costing everyone time and causing individual miss valuable information. Little has been done improve of teams; therefore, we were interested in studying effectiveness leaderboards, common gamification technique, improving participants regular work meetings. Leaderboards comprised data...
Aims The purpose of this study was to compare the prevalence hip displacement and dislocation in a total population children with cerebral palsy (CP) Scotland before after initiation surveillance programme. Patients A 2,155 CP are registered Cerebral Palsy Integrated Pathway (CPIPS) programme, which began 2013. Physical examination radiological data collected according nationally agreed protocols. Methods Age, Gross Motor Function Classification System (GMFCS) level, subtype CP, migration...
Kinematic and kinetic data were obtained from 36 normal children who walked at five different clinically relevant speeds, which mostly slower than speed. Speed groups normalized for body height. significantly affected most of the stride parameters, joint angles, moments, ground reaction force in all three planes motion. The effects speed not always same over whole range speeds studied. clinical relevance these findings is that when comparing pathologic gait characteristics with those...
Twenty-six healthy 7-year-old children were enrolled in a 5-year longitudinal study to examine the importance of age and speed characterization sagittal joint angles, moments, powers. In 740 gait trials, walking at self-selected speeds examined on basis normalized [speed/(height x g)1/2]. The kinematics kinetics these characterized predominantly by progression not age. clinical relevance findings is that walking, rather than age, should be considered when comparing normal with pathologic gait.
This study was designed to assess the impact of gait analysis on treatment patients with cerebral palsy. One hundred two ambulant palsy were assessed clinically and analysis. Separate proposals for each patient recorded after clinical examination The results methods assessment compared. After assessment, 71 102 evaluated recommended a surgical procedure 31 nonoperative treatment. analysis, indications confirmed in 91 cases (89%). Clinical by same orthopedic surgeon close agreement...
In Brief Purpose: To assess the effects of functional electrical stimulation (FES) ankle dorsiflexors and quadriceps in children with cerebral palsy. Methods: Fourteen (mean age 8 years) were randomly allocated to a treatment or control group. The group received 2 weeks neuromuscular followed by FES used at home school. continued its usual physiotherapy program. Assessment took place baseline before after period. Both groups fitted for gait analysis second final assessments. Results: both...
Twenty-six nonoperated spastic hemiplegic children underwent three-dimensional kinetic gait analysis. We identified five patterns based on sagittal plane kinetics. Group I had a minimal disturbance, drop foot pattern, and normal kinetics, II flexed knee but hip extension, III hip, IV hyperextension tibial arrest, V persistent ankle dorsiflexion. concluded that weak anterior muscles, in stance functionally tight gastrocnemius, gastrocnemius flexors, soleus, the patients generated an...
In a prospective, randomised controlled trial, 68 children who had completely displaced metaphyseal fracture of the distal radius were treated either by manipulation (MUA) and application an above-elbow cast alone or additional insertion percutaneous Kirschner (K-) wire. Full radiological follow-up to union was obtained in 65 56 returned for clinical evaluation three months after injury. Maintenance reduction significantly better K-wire group fewer radiographs required. There no significant...
Twenty-six healthy 5-year-old children were enrolled in a 7-year longitudinal study to examine the importance of age and speed characterization ground reaction forces. One thousand forty gait trials walking at self-selected speeds examined on basis normalized [speed/(height x g)(1/2)]. Results, presented as discrete peak trough values continuous trace plots over stance phase, indicated that there was little change forces with age, but significant changes vertical force anterior-posterior...
Kinematic and kinetic data were obtained from 36 normal children who walked at five different clinically relevant speeds, which mostly slower than speed. Speed groups normalized for body height. significantly affected most of the stride parameters, joint angles, moments, ground reaction force in all three planes motion. The effects speed not always same over whole range speeds studied. clinical relevance these findings is that when comparing pathologic gait characteristics with those...
Six children with low-level myelomeningocele underwent gait analysis. All showed excessive ankle dorsiflexion and knee flexion when walking barefoot. A rigid thermoplastic ankle-foot orthosis (AFO) improved by preventing reducing flexion. Biomechanically, the AFO caused a reduction in external moment aligning ground reaction force. Small changes foot-shank angle of had profound effects on mechanics. Knee hyperextension could be controlled rocker sole. Kinetic analysis permits understanding...
Little is currently known about the influence of co-located player audiences on gameplay experience. Social experiences are important to understand in gaming scenarios, because these relate performance. Player-audience relationships have been studied before, but prior research focused attributes and typology. In our study, we investigated effect different audience types (silent, positive, negative) no For contribute a video game specifically developed for two-player, findings from...