Xinyu Zhao

ORCID: 0009-0009-0202-8625
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About
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Research Areas
  • Gut microbiota and health
  • Immune cells in cancer
  • Clostridium difficile and Clostridium perfringens research
  • Gastrointestinal motility and disorders
  • Inhalation and Respiratory Drug Delivery
  • Inflammasome and immune disorders
  • Bacterial biofilms and quorum sensing
  • Bone and Joint Diseases
  • Reproductive System and Pregnancy
  • Immunotherapy and Immune Responses
  • Nuclear and radioactivity studies
  • Immune Response and Inflammation
  • Cell Adhesion Molecules Research
  • Cancer, Hypoxia, and Metabolism
  • Pancreatic and Hepatic Oncology Research
  • Helicobacter pylori-related gastroenterology studies
  • Barrier Structure and Function Studies
  • Psoriasis: Treatment and Pathogenesis
  • Nuclear Materials and Properties
  • Autophagy in Disease and Therapy
  • Immune Cell Function and Interaction
  • Nuclear reactor physics and engineering
  • Osteoarthritis Treatment and Mechanisms

First Affiliated Hospital of Chengdu Medical College
2023-2025

Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2022-2024

Wenzhou Medical University
2022-2024

Zhejiang Institute of Communications
2023-2024

University of Alberta
2024

Abstract Osteoarthritis (OA) is a chronic inflammatory disease characterized by cartilage destruction, synovitis, and osteophyte formation. Disease‐modifying treatments for OA are currently lacking. Because inflammation mediated an imbalance of M1/M2 macrophages in the synovial cavities contributes to progression, regulating M1 M2 polarization can be potential therapeutic strategy. Basing on inherent immune mechanism pathological environment OA, immunoglobulin G‐conjugated bilirubin/JPH203...

10.1002/advs.202400713 article EN cc-by Advanced Science 2024-04-09

A small modular reactor (SMR) is a nuclear that characterized by its smaller size and capacity when compared to traditional large-scale reactors. An SMR often categorized as having an electrical output of less than 300MW built be more mobile, safe, extensible deploy. It has been established SMRs can provide economic flexibility advantages in variety industries thanks the development, study, use multiple types recent years. The goal this paper present comprehensive overview several types,...

10.1109/access.2024.3351220 article EN cc-by-nc-nd IEEE Access 2024-01-01

Fusobacterium nucleatum (F. nucleatum) is closely correlated with tumorigenesis in colorectal cancer (CRC). We aimed to investigate the effects of host norepinephrine on carcinogenicity F. CRC and reveal underlying mechanism. The results revealed that both bacterial quorum sensing (QS) molecule auto-inducer-2 (AI-2) were positively associated progression related (p < 0.01). In vitro studies, induced upregulation QS-associated genes promoted virulence proliferation nucleatum. Moreover,...

10.1080/21505594.2024.2350904 article EN cc-by Virulence 2024-05-09

Abstract Aims Inflammatory bowel disease (IBD) is associated with F. nucleatum, and chronic stress can increase the risk of aggravation. However, whether norepinephrine (NE) enhance pathogenicity nucleatum to aggravate dextran sulfate sodium salt (DSS)-induced colitis unclear. Methods Transcriptome sequencing was used identify differentially expressed genes in bacteria treated NE. Affinity testing molecular docking were applied calculate predict binding NE Quorum sensing regulators C (QseC)....

10.1093/ibd/izae063 article EN Inflammatory Bowel Diseases 2024-03-29
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