A5074652212- Glioma Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging and Pathology Studies
- Neuroendocrine Tumor Research Advances
- Brain Metastases and Treatment
- Neuroblastoma Research and Treatments
- Advanced MRI Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Meningioma and schwannoma management
- Cardiac Imaging and Diagnostics
- MRI in cancer diagnosis
- Monoclonal and Polyclonal Antibodies Research
- Lung Cancer Research Studies
- HER2/EGFR in Cancer Research
- Pediatric Urology and Nephrology Studies
- Parathyroid Disorders and Treatments
- Cell Adhesion Molecules Research
- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Cancer, Hypoxia, and Metabolism
- Craniofacial Disorders and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Genetic and Kidney Cyst Diseases
Baylor College of Medicine
2022-2023
University Hospitals of Cleveland
2019-2022
Case Western Reserve University
2019-2022
University Hospitals Seidman Cancer Center
2021-2022
Cancer Institute (WIA)
2021
Cleveland Clinic
2021
Kettering Medical Center
2014-2020
Wright State University
2014-2019
Memorial Hospital
2016-2019
Kettering Foundation
2018
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Neuroendocrine and Adrenal Gland Tumors focus on the diagnosis, treatment, management of patients with neuroendocrine tumors (NETs), adrenal tumors, pheochromocytomas, paragangliomas, multiple endocrine neoplasia. NETs are generally subclassified by site origin, stage, histologic characteristics. Appropriate diagnosis treatment often involves collaboration between specialists disciplines, using specific biochemical,...
<sup>82</sup>Rb cardiac PET allows the assessment of myocardial perfusion with a column generator in clinics that lack cyclotron. There is evidence quantitation blood flow (MBF) and coronary reserve (CFR) dynamic feasible. The objectives this study were to determine accuracy reproducibility MBF estimates from by using our methodology for generalized factor analysis (generalized sequences [GFADS]) compartment analysis. <b>Methods:</b> Reproducibility was evaluated 22 subjects undergoing rest...
Purpose To assess the safety, biodistribution, and dosimetric properties of positron emission tomography (PET) radiopharmaceutical agent fluorine 18 (18F) FPPRGD2 (2-fluoropropionyl labeled PEGylated dimeric RGD peptide [PEG3-E{c(RGDyk)}2]), which is based on arginine-glycine–aspartic acid (RGD) sequence targets αvβ3 integrin, in first volunteers imaged with this tracer. Materials Methods The protocol was approved by institutional review board, written informed consent obtained from all...
Leptomeningeal metastasis (LM) is a rare but increasingly common condition in which malignant cells migrate to the meninges. The gold standard for diagnosing LM detection of cancer cerebrospinal fluid (CSF). Contrast enhanced-magnetic resonance imaging (CE-MRI) also used diagnose LM. We describe case CE-MRI neuroaxis was initially negative meningeal enhancement F-18 fluorodeoxyglucose positron-emission tomography/computed tomography (F-18 FDG PET/CT) revealed hypermetabolism within lumbar...
A 29-year-old female patient exhibited a solitary neck mass, severe hypercalcemia, and multiple skeletal lytic lesions consistent with metastatic neoplastic disease. Fine-needle aspiration (FNA) cytology of the lesion indicated follicular thyroid neoplasm. CT-guided bone biopsy was non-diagnostic. Subsequent 18F-FDG PET/CT examination demonstrated avid glucose uptake within mass diffuse bony variable metabolic activity. Repeat utilizing guidance produced core tissue classic histologic...
Objectives We tested the hypothesis, in patients with Friedreich's ataxia and no overt structural heart disease, that impairment of cardiac oxidative metabolism may be compensated for either by increased rest myocardial blood flow or more efficient oxygen consumption performance external work. Background is characterized a mutant frataxin gene, which causes mitochondrial iron overload impaired energy production. Further, it frequently associated cardiomyopathy. Studies using magnetic...
Glioblastoma multiforme (GBM) is the most common and lethal malignant glioma in adults. Currently, modality of choice for diagnosing brain tumor high-resolution magnetic resonance imaging (MRI) with contrast, which provides anatomic detail localization. Studies have demonstrated, however, that MRI may limited utility delineating full extent precisely. suggest MR spectroscopy (MRS) can also be used to distinguish high-grade from low-grade gliomas. However, due operator dependent variables...
Renal cyst infection-pyocystis-is a potentially life-threatening complication of autosomal-dominant polycystic kidney disease. Differentiation pyocystis from pyelonephritis is important for antibiotic management. A 56-year-old woman with disease and recurrent urinary tract infections was admitted to the hospital suspicion pyelonephritis. CT static planar In-labeled WBC examinations failed show specific focus infection. Abdominal imaging SPECT/CT revealed abnormal leukocyte accumulation...
One of the treatment options for recurrent brain metastases is surgical resection combined with intracranial brachytherapy. GammaTile® (GT) (GT Medical Technologies, Tempe, Arizona) a tile-shaped permanent brachytherapy device cesium 131 (131Cs) seeds embedded within collagen carrier. We report case treating patient GT and demonstrate dosimetric modeling method.
A 16-year-old male patient with a past medical history of congenital brain malformation presented for surveillance F-FDG PET/CT scan left parotid acinic cell adenocarcinoma. revealed absence gray matter activity in the bilateral cerebral hemispheres most consistent hydranencephaly. Hydranencephaly is rare condition characterized by absent replaced cerebrospinal fluid-filled sacs. The etiology hypothesized to be secondary intrauterine internal carotid artery compromise. Most affected...
Accurate coregistration of computed tomography (CT) and magnetic resonance (MR) imaging can provide clinically relevant complementary information serve to facilitate multiple clinical tasks including surgical radiation treatment planning, generating a virtual Positron Emission Tomography (PET)/MR for the sites that do not have PET/MR system available. Despite long-standing interest in multimodality co-registration, robust, routine solution remains an unmet need. Part challenge may be use...
Abstract Background: Radioiodine therapy for patients with metastatic papillary and follicular thyroid cancer status post total thyroidectomy improves overall survival is standard of care. Physiologic pathologic biodistribution I131 dependent on tissue sodium iodine symporter expression nonspecific radioiodine distribution seen secondary to physiologic routes excretion. Clinical Case: Whole body scintigraphy (WBS) was performed seven days after in a 37-year-old male treated extension...