A5041529705- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Genetic factors in colorectal cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Surgical Treatments
- Systemic Sclerosis and Related Diseases
- Cancer Diagnosis and Treatment
- Salivary Gland Disorders and Functions
- Colorectal and Anal Carcinomas
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
- Microfluidic and Capillary Electrophoresis Applications
- Advanced Biosensing Techniques and Applications
- Esophageal Cancer Research and Treatment
- Wound Healing and Treatments
- Cardiac Arrhythmias and Treatments
- Pharmacological Effects and Toxicity Studies
- Pharmacological Receptor Mechanisms and Effects
- Circular RNAs in diseases
- Radiomics and Machine Learning in Medical Imaging
- Neuroscience and Neural Engineering
- Cancer Genomics and Diagnostics
- Renal and Vascular Pathologies
- Music Technology and Sound Studies
University of Perugia
2023-2024
University of Turin
2023
Istituto Ortopedico Gaetano Pini
2020
University of Messina
2020
Mount Sinai Hospital
2019
University Health Network
2019
STMicroelectronics (Italy)
2018
University of Florence
1996-2014
Fundación para la Investigación, Docencia y Prevención del Cáncer
2012
The presence of lymph node metastasis is one the most important prognostic factors in patients with gastric carcinoma. Node-negative have a better outcome, nevertheless subgroup them experience disease recurrence.To analyze clinicopathological characteristics node-negative advanced carcinoma submitted to gastrectomy and D2 lymphadenectomy retrieved number nodes greater than 15, after an actual follow-up almost 5 years, evaluate outcome indicators.The records 301 who underwent curative for...
An accurate and easy-to-use Q3 system for on-chip quantitative real-time Polymerase Chain Reaction (qPCR) is hereby demonstrated, described in detail. The qPCR reactions take place inside a single-use Lab-on-a-Chip with multiple wells, each 5 to 15 µL capacity. same chip hosts printed metal heater coupled calibrated sensor, rapid temperature control the reaction mixture. rest of non-disposable encased 7 × 14 8.5 (height) cm plastic shell weighing 300 g. Included part fluorescence read-out...
The relationship between the number of lymph nodes examined and outcome in patients with node-negative (N(-)) gastric cancer was studied. We compared N(-) to those nodal involvement (N(+)) identify clinicopathologic characteristics cancer. Finally, we evaluated indicators this group patients.Of 367 patients, 130 (35.4%) were N(-). These stratified according main prognostic variables, assess differences N(+) cases. A statistical analysis using Cox model performed estimate indicators.N(-)...
There is a great deal of controversy regarding the definition, classification, and staging cardiac adenocarcinoma (CA). Recently, shift from distal to proximal lesions has been documented in gastric cancer. We have stratified our cases cancer as CA, (DGC), stump (SC).Between 1986 1998, 450 patients with were operated on at institute. The resectability rate was 81.6%. Of 367 patients, 48 298 DGC, 21 SC. These 3 groups compared terms clinicopathologic factors survival rates.CA significantly...
Background and Aims: The complication rate after surgery for gastric cancer varies according to the particular definition of morbidity, so it’s necessary report them using a standardized method, Clavien-Dindo system. purpose this study was prospectively analyze all post-gastrectomy complications in patients with adenocarcinoma severity grade system, order identify risk factors postoperative their prognostic significance on survival. Methods: This is based data from 90 consecutive who...
Background and Objectives The relationship between the number of lymph nodes examined outcome in patients with node-negative (N−) gastric cancer was studied. We compared N− to those nodal involvement (N+) identify clinicopathologic characteristics cancer. Finally, we evaluated indicators this group patients. Methods Of 367 patients, 130 (35.4%) were N−. These stratified according main prognostic variables, assess differences N+ cases. A statistical analysis using Cox model performed estimate...
Gastric cancer remains a major health problem despite its decline in incidence Western countries. Although radical surgery represents the primary curative option for gastric patients, most of them relapse and die due to their disease an R0 resection. At present routine use postoperative adjuvant therapy reduce recurrence is still considered investigational approach. Out total 275 patients (stage IB through IV M0 AJCC/UICC) who underwent at our Surgery Unit between 1993 2001, 156 were...
<h3>Background:</h3> Primary Sjögren's syndrome (pSS) is characterized by a highly heterogeneous phenotype driven different clinical manifestations and an unpredictable course. Moreover, up to 15% of patients may develop systemic about 45% accumulate permanent damage after 5-10 years disease. However, no study evaluated at longer follow-up nor analysed disease phenotypes which, baseline, identify patient clusters higher risk accrue irreversible damage. <h3>Objectives:</h3> To evaluate...
We studied the pharmacokinetics of glutamate antagonist NBQX (6-nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione) in 16 normal male volunteers aged 18--37 years a double-blind, placebo-controlled design. Intravenous infusions 0.0075 and 0.03 mg kg(minus sign1) over 30 min were given to six subjects at each dose level (parallel groups). Two received placebo. The drug was well tolerated no clinically significant alterations cardivascular or renal function biochemical hematological parameters...
The aim of this study was to evaluate the accuracy multiple detector computed tomography (MDCT) in preoperative staging gastric cancer, prospectively comparing CT findings with pathological at surgery, a single-center study. A total 19 consecutive patients primary cancer recruited between March and July 2014 were submitted MDCT according standard protocol. All diagnostic procedures performed by dedicated radiologists who unaware final results. Subsequently, 16 underwent surgical treatment 15...
Among the emerging applications of music scores we can see production and adoption multimedia digital objects based on score for distance learning/tuition music, etc. In these applications, notation model has to provide distinct mechanisms modeling symbolic visual aspects defining relationships among such in particular between audio files real performance. This paper explains capabilities WEDELMUSIC regarding synchronization execution synchronous with files. The functionality is supported by...
Introduction: Despite major progress in closure techniques for endoscopic endonasal skull base surgery (EESBS), cerebrospinal fluid (CSF) leakage remains a common complication. Regenerated oxidized cellulose (ROC) (Surgicel¸ Ethicon, United States) sheets are often used as an adjunct to reconstruction provide hemostasis and promote adherence of reconstructive tissues. However, evidence supporting its impact on the healing process is uncertain several publications have raised concerns about...
Although the prognosis of early gastric cancer (EGC) is considered to be satisfactory, some patients experience tumor relapse after curative surgery. Both pathogenesis and risk factors recurrence remain unclear. We describe a case report 49-year-old male who underwent subtotal resection D2A for angular cancer. Histological examination revealed adenocarcinoma with low grade differentiation colloid areas, intramucosal, absence neoplastic proliferation in surgical margins, omental stroma six...
<h3>Background</h3> Sjögren's syndrome (SS) represents a chronic autoimmune disorder characterized by relatively benign course. However, up to 40% of SS patients develop systemic extra-glandular involvement which, in turn, may lead long-term damage accrual. Few studies assessed accrual with follow-up ranging from 5 10 years. Knowledge risk and awareness factors contributing represent important issues identify requiring closer better stratify therapy. <h3>Objectives</h3> To examine disease...
Breast cancer therapy may fail due to the disease's limiting pathogenesis processes, including as epithelial-mesenchymal transition (EMT), stem cells (CSCs), and drug resistance. Functionally significant mediators in these pathogenic processes include lncRNAs miRNAs, which are master regulators of gene expression. Complex regulatory networks post-transcriptional control formed by intricate crosstalks between non-coding RNAs. The lncRNA-miRNA axis have tumor suppressor or oncogenic effects...