About
Contact & Profiles
A5053901986
Research Areas
- Astrophysics and Cosmic Phenomena
- DNA and Nucleic Acid Chemistry
- Particle accelerators and beam dynamics
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Neutrino Physics Research
Zhejiang University of Technology
2024
Chinese Academy of Sciences
2024
Despite the well-established significance of transcription factors (TFs) in pathogenesis, their utilization as pharmacological targets has been limited by inherent challenges modulating protein interactions. The lack defined small-molecule binding pockets and nuclear localization TFs do not favor use traditional tools. Aptamers possess large molecular weights, expansive blocking surfaces efficient cellular internalization, making them compelling tools for TF Here, we report a...
10.1038/s41467-024-51197-w
article
EN
cc-by-nc-nd
Nature Communications
2024-08-08
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