A5081805036- Plant and animal studies
- Gastric Cancer Management and Outcomes
- Plant Ecology and Taxonomy Studies
- Genetic factors in colorectal cancer
- Gastrointestinal Tumor Research and Treatment
- Plant Pathogens and Fungal Diseases
- Epigenetics and DNA Methylation
- Microbial Community Ecology and Physiology
- Acupuncture Treatment Research Studies
- Botanical Studies and Applications
- Genetic diversity and population structure
- Gut microbiota and health
- Plant and Fungal Species Descriptions
- Helicobacter pylori-related gastroenterology studies
- Plant Diversity and Evolution
- Species Distribution and Climate Change
- Cancer Cells and Metastasis
- Esophageal Cancer Research and Treatment
- Genomics and Phylogenetic Studies
- Environmental DNA in Biodiversity Studies
- Pancreatic function and diabetes
- Reproductive biology and impacts on aquatic species
- Photodynamic Therapy Research Studies
- Bariatric Surgery and Outcomes
- Ovarian cancer diagnosis and treatment
Chinese Academy of Forestry
2021-2025
Second Affiliated Hospital of Zhejiang University
2019-2025
Institute of Forest Ecology, Environment and Protection
2021-2025
Beijing Forestry University
2016-2021
Zhejiang Chinese Medical University
2021
Wenzhou Hospital of Traditional Chinese Medicine
2021
Wenzhou Medical University
2019-2020
First Affiliated Hospital of Wenzhou Medical University
2019-2020
Guangzhou University
2018
Harbin Medical University
2013-2016
Objectives To investigate sex difference in global gastric cancer incidence by year, age and socioeconomical status. Design An international comparative study. Setting We obtained the national sex-specific of caner year from Global Burden Disease Study 2017. The human development index (HDI) 2017 as an indicator status was extracted Human Development Report. Main outcome measures Sex-specific compared at level. Linear regression analyses were performed to explore socioeconomic-associated...
Background: Ischemic stroke is a common disease with poor prognosis, which has become one of the leading causes morbidity and mortality worldwide. Astragaloside IV (AS-IV) main bioactive ingredient Astragali Radix (which been used for ischemic thousands years) found to have multiple bioactivities in nervous system. In present study, we aimed explore neuroprotective effects AS-IV rats cerebral ischemia/reperfusion (CIR) injury targeting Sirt1/Mapt pathway. Methods: Sprague–Dawley (male,...
Abstract Invasive plants can profoundly disrupt native biodiversity, yet the genetic mechanisms underpinning their success remain poorly understood. To date, genomic studies have been conducted on only a limited number of invasive species, and no single-cell level applied. This research investigates drivers behind behavior common reed ( Phragmites australis ), hardy grass species that became in North America following its introduction from Europe. By integrating whole-genome sequencing with...
This study investigated the contribution of survivin and its upstream regulators, AKT hypoxia‐inducible factor 1α ( HIF –1α), to resistance gastric cancer cells cisplatin CDDP ). We found that over‐expression increased SGC 7901 BGC 823 . Its abrogated ‐induced inhibition cell proliferation apoptosis. In contrast, down‐regulation expression using small hairpin RNA (sh ) vectors small‐molecule inhibitor YM 155, or function a recombinant cell‐permeable dominant‐negative protein (d NS ur9),...
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers with an estimated 1.8 million new cases worldwide and associated high mortality rates 881 000 CRC-related deaths in 2018. Screening programs therapies have only marginally improved survival CRC patients. Immune-related genes (IRGs) attracted attention recent years as therapeutic targets. The aim this study was to identify immune-related prognostic signature for CRC. To end, we combined gene expression clinical data from...
Two complete chloroplast genome sequences of Asteropyrum, as well those 25 other species from Ranunculaceae, were assembled using both Illumina and Sanger sequencing methods to address the structural variation cp controversial systematic position genus. Synteny plastome structure compared across family. The genomes only two subspecies Asteropyrum found be differentiated with marked sequence different inverted repeat-single copy (IR-SC) borders. plastomes contains 112 genes. However, IR...
USP21 is a kind of deubiquitinating enzymes involved in the malignant progression various cancers, while its role gastric cancer (GC) and specific molecular mechanism are still unclear. This study probed into function vitro vivo , discussed regulatory GC . We reported that promoted cell proliferation, migration, invasion, stemness regulated tumor growth mice stabilized expression GATA3 by binding to GATA3. Besides, also MAPK1 at transcriptional level. A series experiments testified...
This study investigates the role of CALCR, a G-protein-coupled receptor, in gastric cancer (GC) progression and its interaction with ANTXR1. A total 121 patients were enrolled from Department General Surgery, Anyang Tumor Hospital, City, Henan Province, China. 218 tumor tissues corresponding para-carcinoma collected 109 patients, while adjacent retained remaining 12 cases. Kaplan-Meier analysis evaluated prognostic value m6A-related genes GC. Immunohistochemistry (IHC) was conducted to...
ABSTRACT Microorganisms are regarded as the key driver in regulating biogeochemical cycles. A comprehensive examination of riverine microbial community composition and structure is crucial for understanding functions aquatic ecosystems. However, previous studies mainly focused on spatial distribution microorganisms main stems rivers, ignoring shifts communities along streams, tributaries, rivers. To address this gap, we collected water samples from 27 sites Yangtze River Source Region...
Gastrointestinal stromal tumors (GISTs), with a primary occurrence in the duodenum and proximal jejunum, are rare treatment is poorly understood. This study aimed to evaluate main factors influencing prognosis of GIST resection this complex anatomical structure.This retrospective included 47 patients who underwent surgery for (20) jejunum (27) between 2012 2017. Perioperative clinical data as well relapse survival information were collected.All negative margin (R0) duodenal GISTs....
White pines (Pinus subsect. Strobus) play important roles in forest ecosystems the Northern Hemisphere. Species of this group are narrowly distributed or endangered China. In study, we used a species distribution model (SDM) to project and predict patterns 12 Chinese white pine under variety paleoclimatic future climate change scenarios based on 39 high-resolution environmental variables 1459 records. We also computed centroid shift, range expansion/contraction, suitability current area...
Milu (Père David's deer, Elaphurus davidianus), once extinct in the wild, was one of few indigenous large herbivores wetland ecosystem China. The reintroduction milu northern China has just started and is expected to restore not only that species, but also ecosystem. To acquire insights into adaptive process population first rewilded habitat provide knowledge for on-going future attempts, we used DNA metabarcoding analyze diets gut microbiota those year after releasing. results showed strong...
Hepatoid adenocarcinoma of the stomach (HAS) is a particular subtype Gastric cancer (GC) with distinct pathological characteristics and genetic profile, but most HAS patients were received identical regimens as common GC. To date, only few studies has been conducted to investigate molecular HAS, which may prevent rational application new anticancer strategies. further obtain features potential predictive prognostic biomarkers our current study evaluated clinical implications spectrum markers...
The morphologically based taxonomic status of Clematis acerifolia var. elobata has been controversial. This study used two nuclear (ITS and ETS) six plastid (rps16, rpl16, accD, trnS-trnG, atpB-rbcL, trnV-atpE) molecular markers, a DNA barcoding analysis to address the C. relationship among other species. Our results showed that discrimination power ITS, ETS, atpB-rbcL was better than tested regions. When all sequences combined, most sampled taxa were resolved. Though are closely related,...
Interspecific hybridization is common and has often been viewed as a driving force of plant diversity. However, it raises taxonomic problems thus impacts biodiversity estimation biological conservation. Although previous molecular phylogenetic studies suggested that interspecific may be rather in Clematis, artificial widely applied to produce new Clematis cultivars for nearly two centuries, the issue natural never addressed detail. In this study, we tested hybrid origin mesophytic...
Aims:The purpose of establishing national parks in China is to protect the integrity and authenticity natural ecosystems promote biodiversity conservation.Evaluation a prerequisite for studies such as layout planning, boundary range determination, functional zoning parks.To assess status parks, this study provided method which data are easily accessible, assessment methods simpler, results clearly understood by decision-makers, managers, public.Methods: Based on structure function...